Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling by Chung, Jihyun

“…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …”
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The effect of clopidogrel and aspirin on the severity of traumatic brain injury in a rat model by Firas, Kobeissy

“…TBI increases UCHL-1 and GFAP, but decreases hexokinase expression compared to the non-injured controls. …”
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Biodegradable polysaccharide grafted polyacrylamide inhibitor for corrosion in CO2- saturated saline solution by Jalab, Rem

“…Lastly, potentiostatic testing of steel with AGGPAM at an applied potential of 50 mV illustrated surface protection and decreased current over a prolonged time. …”
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Optimal virtual network function placement in multi-cloud service function chaining architecture by Bhamare, Deval

“…Greedy approach has already been widely studied in the literature for the VM placement problem. Especially we compare our proposed heuristic with a greedy approach using first-fit decreasing (FFD) method. …”
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Contrasting cardiovascular mortality trends in Eastern Mediterranean populations: Contributions from risk factor changes and treatments by Critchley, Julia

“…Results Risk factor trends: Smoking prevalence was high in men, persisting in Syria but decreasing in Tunisia, oPt and Turkey. BMI rose by 1-2 kg/m2 and diabetes prevalence increased by 40%-50%. …”
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Vertical zonation and functional diversity of fish assemblages revealed by ROV videos at oil platforms in The Gulf by Ben-Hamadou, Radhouan

“…To assess the local fish community, a total of 242 videos amounting to twenty-one hours of observation were selected randomly, however, if no fish appear in a selected video a new video was randomly selected from the list. …”
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Estimation of Mechanical Properties of Copper Powder Filled Linear Low-Density Polyethylene Composites by Singh, S.

“…Conclusion: In line with the experimental data, we found that as we increased the volume fraction of the copper powder, the elongation and stress at break of the composites decreased, while the Young’s modulus increased.…”
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The mitochondria: A target of polyphenols in the treatment of diabetic cardiomyopathy by Bhagani, Humna

“…The most important intermediates by which polyphenols exert their protective effect include Bcl-2, UCP2, SIRT-1, AMPK and JNK1. Bcl-2 acts to attenuate apoptosis, UCP2 decreases oxidative stress, SIRT-1 increases mitochondrial biogenesis and decreases oxidative stress, AMPK increases autophagy, and JNK1 decreases apoptosis and increases autophagy. …”
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Does Securitisation Make Monetary Policy Less Effective? by Qanas, Jalal

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Impact of composition and salinity on swelling and gel strength of poly (acrylamide-co-acrylic acid) preformed particle gel by Ben Ali, Ahmed

“…The effects of various material compositions and reservoir environments on the ultimate strength and swelling kinetics of a commercial preformed particle gel (PPG) have been investigated. …”
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Factors associated with meeting current recommendation for physical activity in scottish adults with diabetes by Salman A.

“…Furthermore, meeting the recommended physical activity levels decreased with age (OR 0.96; 95% CI 0.95–0.97), having a longstanding illness (OR 0.56; 95% CI 0.34–0.93) and body mass index (OR 0.94; 95% CI 0.92–0.97), but increased with higher fruit and vegetable intake (OR 1.16; 95% CI 1.07–1.25) and mental wellbeing (OR 1.04; 95% CI 1.02–1.06). …”
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Mangifera indica L. kernel ethanol extract inhibits cell viability and proliferation with induction of cell cycle arrest and apoptosis in lung cancer cells by Alshwyeh, Hussah Abdullah

“…In this study, we investigated the effects of an ethanolic extract of Mangifera indica L. kernel on the viability and proliferation of human lung cancer cells. …”
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Edge-based compression and classification for smart healthcare systems: concept, implementation and evaluation by Awad Abdellatif A.

“…Our experimental results assess the performance of the proposed system in terms of data reduction, classification accuracy, battery lifetime, and transmission delay. We show the effectiveness of our system and its ability to outperform conventional remote monitoring systems that ignore data processing at the edge by: (i) achieving 98.3% classification accuracy for seizures detection, (ii) extending battery lifetime by 60%, and (iii) decreasing average transmission delay by 90%.…”
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Natural aging of shape stabilized phase change materials based on paraffin wax by Krupa, Igor

“…The addition of 15 wt% of EG to shape stabilized phase change materials (SSPCMs) containing 50 wt% of wax caused a decreasing in the leakage of wax by 50% over 210 days of natural aging. …”
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Effect of the length of silicon nano-dot/wire on band gap by Hassan, Walid M.I.

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EdgeHealth: An Energy-Efficient Edge-based Remote mHealth Monitoring System by Emam A.

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Towards Extended Bit Tracking for Scalable and Robust RFID Tag Identification Systems by Fahim A.

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The investigation of treatment design parameters on carbon integration networks by Alnouri, Sabla Y.

“…Furthermore, it was discovered that for net capture targets of 20% and 25%, no revenue from carbon storage could be generated beyond a solvent temperature of 25 °C. Additionally, the optimal diameter of the treatment column was more responsive to changes in solvent temperature for cases with low net capture targets (below 10%), while its sensitivity decreased for higher capture targets (above 10%). …”
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Predicting academic success in health professions training and education: Insights from a data mining analysis by Bragazzi, Nicola Luigi

“…For the Academic Years 2008-2009 and 2009-2010 results of ad hoc psychological questionnaires investigating, among others, motivation and possible influences from the peer environment were also available. We found that attendance to the so called ‘tirocinio,’ an Italian word describing practical training activities and clinical placements, is the most important variable in terms of variance and that administrative social-demographic variables alone are sufficient to explain school success and achievement (AUC 0.99500 for 2007, AUC 0.98774 for 2008 and AUC 1.00000 for 2009). …”
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Investigating the utilization of healthcare services to manage respiratory tract infections (RTIs) among Qatari patients attended selected primary healthcare centers in Qatar by Islam, Nazmul

“…Highest number of patients with a comorbidity of Diabetes (12.85%), followed by Hypertension (10.54%). We have found no difference in the month-to-month rates of RTI-related GP visits (per 1000 total visits) over the study period (non-significant decreasing trend). …”
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