PRMT5-PTEN molecular pathway regulates senescence and self-renewal of primary glioblastoma neurosphere cells by Banasavadi-Siddegowda, Y K

“…Here, we report the critical role of PRMT5 in GBM differentiated cells (GBMDC) grown in serum and GBM neurospheres (GBMNS) grown as neurospheres in vitro. …”
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VEGF-121 plasma level as biomarker for response to anti-angiogenetic therapy in recurrent glioblastoma. by Martini, Maurizio

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An integrative bioinformatics pipeline to demonstrate the alteration of the interaction between the ALDH2*2 allele with NAD and Disulfiram. by J, Christy Priyadharshini

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Divergent changes of the elevational synchronicity in vegetation spring phenology in North China from 2001 to 2017 in connection with variations in chilling by Dai, Junhu

“…Mountain ecosystems are sensitive to climate change, and vegetation phenology provides one of the best signals to exemplify ecosystem responses to climate change. …”
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Conversion of a mixture of date palm wastes to mesoporous activated carbon for efficient dye adsorption by Alharbi, Hattan A.

“…Maximum removal of RBBR was achieved at pH 3 (96.69 mg g−1) and at 30 °C of solution temperature (85.79 mg g−1). …”
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Reversal of insulin resistance in overweight and obese subjects by trans-resveratrol and hesperetin combination—link to dysglycemia, blood pressure, dyslipidemia, and low-grade inf... by Rabbani, Naila

“…Changes in CCL2, IL-8, and RAGE were intercorrelated and all correlated positively with changes in MLXIP, MAFF, MAFG, NCF1, and FTH1, and negatively with changes in HMOX1 and TKT; changes in IL-8 also correlated positively with change in COX-2. …”
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Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice by Ayman, Alzu'bi

“…These findings were found to be correlated with increased level of oxidative stress, neuroinflammation, and apoptosis markers, and reduced expression of brain-derived neurotrophic factor (BDNF), which plays an essential role in modulating synaptic plasticity integral for promoting learning and memory in the hippocampus. Additionally, we showed that AB-FUBINACA significantly decreased the expression of NR1, an important functional subunit of glutamate/NMDA receptors and closely implicated in the development of toxic psychosis. …”
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Scalable Containerized Pipeline for Real-time Big Data Analytics by Aurangzaib, Rana

“…The proposed solution yields a x 1.31 to x 2.4 increase in throughput, and x 32 to x 80 decreased latency compared to the commonly used static resource allocation strategy for data pipelines. 2022 IEEE.…”
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Novel, selective EPO receptor ligands lacking erythropoietic activity reduce infarct size in acute myocardial infarction in rats by Kiss, K.

“…In study 4, AF43136 at 10 mg/kg decreased infarct size, similarly to the positive control CsA compared to the appropriate vehicle (39.4 ± 5.9% vs. 58.1 ± 5.4% and 45.9 ± 2.4% vs. 63.8 ± 4.1%, p < 0.05, respectively). …”
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Omega-3 fatty acid-rich fish oil supplementation prevents rosiglitazone-induced osteopenia in aging mice by Cugno, Chiara

“…Rosiglitazone is an effective insulin-sensitizer, however, associated with bone loss mainly due to increased bone resorption, and bone marrow adiposity, and decreased bone formation. We investigated the effect of the co-administration of fish oil (FO) rich in omega-3 fatty acids (FAs) on rosiglitazone (RSG)-induced bone loss in aging C57BL/6 mice and the mechanisms underlying potential preventive effect. …”
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Graph-Guided Regularized Regression of Pacific Ocean Climate Variables to Increase Predictive Skill of Southwestern U.S. Winter Precipitation by Tejedor, Alejandro

“…We use large ensemble simulations from a climate model to construct this regularizer, reducing the structural uncertainty in the estimation. …”
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Impact of the Wireless Network's PHY Security and Reliability on Demand-Side Management Cost in the Smart Grid by El Shafie, Ahmed

“…To further secure the smart meters' transmissions and enhance their reliability, we propose a new encoding scheme where the data are encoded over the available smart meters' communication (i.e., non-idle) times in a given hour.…”
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Inhibitory effect of sodium nitrite on corrosion of lead in 0.1 M sodium hydroxide solution by Mourad, M.Y.

“…The maximum inhibition efficiency is found to be 49.4% at 35°C and 45.9% at 50°C.…”
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Electronic vs Ionic limitations to electrochemical performance in Li4Ti5O12-based organic suspensions for lithium-redox flow batteries by Madec, L.

“…Here, we report the electrochemical response of the LTO/KB anolytes vs. lithium as function of the cycling rate in static mode (i.e. no flow) and using a home-made cell. …”
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Specific bioactive compounds in ginger and apple alleviate hyperglycemia in mice with high fat diet-induced obesity via Nrf2 mediated pathway by Sampath, Chethan

“…Phloretin and [6]-gingerol also decreased the levels of AGEs and CML levels, via Nrf2 pathway, enhancing GSH/GSSG ratio, heme oxygenase-1 and glyoxalase 1 in liver tissue. …”
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Community structure and activity of a highly dynamic and nutrient-limited hypersaline microbial mat in Um Alhool Sabkha, Qatar by Al-Thani, Roda

“…The Um Alhool area in Qatar is a dynamic evaporative ecosystem that receives seawater from below as it is surrounded by sand dunes. We investigated the chemical composition, the microbial activity and biodiversity of the four main layers (L1-L4) in the photosynthetic mats. …”
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Novel Isosteviol Derivatives Induced Apoptosis In Human Lung Cancer by Malki, Ahmed

“…Cancer metastasis is the major cause of cancer death. We previously reported novel isosteviols derivatives which induced cytotoxicity in lung cancer cells. …”
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Kappa-Distributed Electrons in Solar Outflows: Beam-Plasma Instabilities and Radio Emissions by Lazar, M.

“…We investigate, both theoretically and numerically, three electron plasma beam configurations with different implications in the generation of radio emissions. …”
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Amlexanox-loaded nanoliposomes showing enhanced anti-inflammatory activity in cultured macrophages: A potential formulation for treatment of oral aphthous stomatitis by Abouzid, Afaf

“…Notably, %TNF-α dramatically decreased to 57 ± 4.05% of control, for cells treated with drug-free liposomes (500 μg/mL total lipid) indicating the anti-inflammatory activity of SPC lipid component per se, which led to synergistic effect as evident from the augmentation of AMX anti-inflammatory activity in D-L1 formulation. …”
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Correlating the microstructure to mechanical properties and wear behavior of an accumulative back extruded Al-Mg2Si in-situ composite by Ebrahimi, M.

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