Combination of DNA Damage, Autophagy, and ERK Inhibition: Novel Evodiamine-Inspired Multi-Action Pt(IV) Prodrugs with High-Efficiency and Low-Toxicity Antitumor Activity by Xiao-Meng Liu (778197)

“…Among them, compound <b>10</b> exhibited a 118-fold enhancement in the IC₅₀ value compared to cisplatin and low toxicity to normal cells. …”

Combination of DNA Damage, Autophagy, and ERK Inhibition: Novel Evodiamine-Inspired Multi-Action Pt(IV) Prodrugs with High-Efficiency and Low-Toxicity Antitumor Activity by Xiao-Meng Liu (778197)

“…Among them, compound <b>10</b> exhibited a 118-fold enhancement in the IC₅₀ value compared to cisplatin and low toxicity to normal cells. …”

Combination of DNA Damage, Autophagy, and ERK Inhibition: Novel Evodiamine-Inspired Multi-Action Pt(IV) Prodrugs with High-Efficiency and Low-Toxicity Antitumor Activity by Xiao-Meng Liu (778197)

“…Among them, compound <b>10</b> exhibited a 118-fold enhancement in the IC₅₀ value compared to cisplatin and low toxicity to normal cells. …”

Combination of DNA Damage, Autophagy, and ERK Inhibition: Novel Evodiamine-Inspired Multi-Action Pt(IV) Prodrugs with High-Efficiency and Low-Toxicity Antitumor Activity by Xiao-Meng Liu (778197)

“…Among them, compound <b>10</b> exhibited a 118-fold enhancement in the IC₅₀ value compared to cisplatin and low toxicity to normal cells. …”

Data_Sheet_5_Decreased default mode network functional connectivity with visual processing regions as potential biomarkers for delayed neurocognitive recovery: A resting-state fMRI... by Zhaoshun Jiang (7478243)

<i>In vitro</i> treatment with the broad spectrum caspase inhibitor Q-VD-OPh reduces the number of active caspase-3-positive cells in parallel with a decrease in the entry of micro... by María Martín-Estebané (623506)

Mean (+/− SE) motor-evoked potential (MEP) amplitude during the RT interval expressed as a percentage of maximal MEP (Mmax) for 10 ms time bins prior to EMG onset. by Michael Kennefick (663034)

Expressed A-p50 exhibits biological activity in A549 cells by Jing Mi (18654)

“…Ad-A-p50-infected A549 cells show a decrease in nuclear NF-κB p50 expression (Ad-A-p50) compared with Ad-siNT-infected A549 cells. …”

Relative change in catch for the last 20 years of projection for 50% increase in fishing effort of crustaceans (ICRUS50%), a 50% increase in fishing effort for crustaceans and finf... by Javier Porobic (6392612)

“…Note that the y-axes is the ratio of change against the starting conditions—so a -0.5 result indicates a 50% decrease and a 0.5 result indicates a 50% increase -.…”

The characteristics of the nine biathletes and eight cross-country skiers participating in this study (mean ± SD). by Harri Luchsinger (3178887)

Influence of baseline anemia and newly observed anemia on mean infarct sizes and infarct growth. by Sebastian Bellwald (5165984)

TGF-β1 and IL-10 decreased in the Tregs depletion group and TGF-β1 may contribute to the Th17 cells differentiation. by Laiyu Song (165245)

Overexpression of miR-26a lead to reduced cell viability and decreased clonogenicity. by Jie Gao (10266)

Propofol increased the number of the hippocampal pyramidal neurons and decreased the expression of the LC3-II protein and the number of lysosomes and autophagosomes in the ischemic... by Derong Cui (326839)

“…<p>I/R was induced by 2-vessel occlusion. Propofol 10, 50, or 100 mg/kg was administrated intraperitoneally and 3-MA (600 nM) was administered intracerebroventricularly 10 min after the onset of ischemia. (1) Sham-operated group (control group, Cont); (2) I/R group; (3) I/R+ 3-MA 600 nmol group; (4) I/R + propofol 10 mg/kg group; (5) I/R + propofol 50 mg/kg group; (6) I/R + propofol 100 mg/kg group; (7) I/R + vehicle (intralipid, 100 mg/kg) group. …”

Data_Sheet_4_Decreased default mode network functional connectivity with visual processing regions as potential biomarkers for delayed neurocognitive recovery: A resting-state fMRI... by Zhaoshun Jiang (7478243)

Data_Sheet_3_Decreased default mode network functional connectivity with visual processing regions as potential biomarkers for delayed neurocognitive recovery: A resting-state fMRI... by Zhaoshun Jiang (7478243)

Data_Sheet_1_Decreased default mode network functional connectivity with visual processing regions as potential biomarkers for delayed neurocognitive recovery: A resting-state fMRI... by Zhaoshun Jiang (7478243)

Data_Sheet_1_Decreased default mode network functional connectivity with visual processing regions as potential biomarkers for delayed neurocognitive recovery: A resting-state fMRI... by Zhaoshun Jiang (7478243)

Data_Sheet_2_Decreased default mode network functional connectivity with visual processing regions as potential biomarkers for delayed neurocognitive recovery: A resting-state fMRI... by Zhaoshun Jiang (7478243)

Inhibition of PKCδ causes a decrease in viral replication. by Brian D. Carey (6092747)