2-CDA decreases PIN 1 protein levels in 7WD10 cells. by Crystal D. Hayes (304487)

“…(B) ImageJ quantitation revealed significantly decreased PIN 1 protein levels at 0.1 mM (39%, p<0.001), at 0.5 µM (30%, p<0.001), 1.0 µM (24%, p<0.001), 5.0 µM (19%, p<0.001) and 10.0 µM (29%, p<0.001) compared to untreated control cells n = 4 in each group. *, p<0.05, **, p<0.01, vs. untreated controls.…”

Curcumin induces phosphorylation of p38 MAPK and decreases phosphorylation of Akt in RPE cells. by Margrit Hollborn (394459)

“…Curcumin was tested at 50 and 100 µM. <b>C.</b> Dose-dependence of the curcumin effect on the phosphorylation level of Akt. …”

Poly I:C stimulation significantly decreased the number of lysozyme positive cells in enteroids. by Julie M. Davies (412514)

Retinoic acid improved cell morphology and decreased the number of hypertrophic cells in LT cultures. by Carmen Retana (479628)

“…<p>(<b>A</b>) Omentum-derived mesothelial cells (control) and effluent-derived mesothelial cells from LT and HT grown until confluence in the presence of ATRA (0, 50, 100 and 200 nM). …”

The interaction of FasL with Fas decreases the survival rate of mice with an influenza virus infection. by Daisuke Fujikura (280848)

A genetic deficit in endothelial c-kit expression decreases colony-forming VESCs and results in impaired EC proliferation and angiogenesis, and retardation of tumor growth in vivo. by Shentong Fang (127331)

Decreased ISCs and increased goblet cells after intestinal specific loss of MLL1. by Neha Goveas (11790822)

“…Right panels; enteroendocrine cells stained with chromogranin A antibody (brown; arrowheads) in the villi. Scale bars are 100 μm. …”

Velocity fields in patients’ CA show the transition to laminar flow with decreased flow velocity. by Mary Hammes (2609983)

Decreasing neural activity in MBONs that suppress PER when activated has modest effects. by Justine Chia (5459294)

Simvastatin decreases cerebral vasospasm of the middle cerebral artery and reduces microthromboemboli after SAH. by Mohammed Sabri (355717)

“…Representative images from immunohistochemical staining of fibrinogen show the presence of numerous microthromboembli in SAH animals treated with vehicle (arrow heads) but only few in animals treated with simvastatin either pre- or post-SAH, and none in the naïve controls. Scale bar is 100 µm. <b>D</b> and <b>E</b>. Both pre-SAH and post-SAH treatment with simvastatin significantly decrease microthromboemboli in both cerebral cortex (<i>P</i><0.001) and hippocampus (<i>P</i><0.01) as compared to vehicle treated group. …”

RIG-I deficient mice demonstrate decreased protection against heterologous IAV challenge. by Matheswaran Kandasamy (105167)

Hsp90 inhibition decreases the adipogenic transcriptional program without any effect on cytotoxicity. by Sébastien Desarzens (547289)

DCD is strikingly decreased in HS lesions. by Margaret Coates (6058580)

“…Co-staining was performed with K77 (green), which is a marker of eccrine sweat glands. Scale bar is 100μm. …”

hESCs-Exo decreased cancer cell proliferation and increased cancer cell death. by Shufeng Zhou (398572)

Sholl analysis of immature neurons indicates decreased complexity of the dendritic arbors in <i>Disc1</i>^100P/100P mice (A–C). by Jayanth S. Chandran (637420)

Exposure to low CO₂ levels decreases ER cholesterol levels. by Nityanand Bolshette (17396845)

“…<b>(B)</b> Bioluminescence recordings from the different conditions as depicted in <b>(A)</b>, the arrow indicates the time CO₂ was shifted from 5% to 1% (mean ± SE, <i>n</i> = 4 biological replicates per condition, AUC for 0 mM 0.34 ± 0.007, 1.59 ± 0.004 (<i>P</i> < 0.0001), 0.5 mM 1.00 ± 0.023, 2.68 ± 0.04 (<i>P</i> < 0.0001), 1 mM 1.66 ± 0.07, 3.34 ± 0.04 (<i>P</i> < 0.0001), 3 mM 2.06 ± 0.02, 2.79 ± 0.07 (<i>P</i> < 0.0001), 5 mM 2.02 ± 0.05, 2.43 ± 0.06 (<i>P</i> < 0.002), 7 mM 1.85 ± 0.01, 1.77 ± 0.02 (<i>P</i> < 0.02) two-sided Student’s <i>t</i> test). …”

Rho kinase (ROCK) inhibitors promote neurite elongation of human model neurons. by Frank Roloff (695802)

Ibuprofen increased neurite length of human model neurons. by Frank Roloff (695802)

RhoA and Rho kinase inhibitors promote initiation of neurites. by Frank Roloff (695802)

Global Land Use Change Impacts on Soil Nitrogen Availability and Environmental Losses by Jing Wang (6206297)

“…Anthropogenic activities, particularly land use change and management practices, alter the global nitrogen (N) cycle. As a central part of the global N cycle, soil N supply from net N mineralization (NNM) and net nitrification (NN) contributes to over 50% of crop N uptake. …”