Lack of CHOP protein does not protect T17M <b><i>RHO</i></b><b> retinas from degeneration, as measured by scotopic ERG responses at 10DB.</b> by Sonali Nashine (408442)

“…<p>We analyzed 4 groups of animals (N = 6). A: The a-wave of the scotopic ERG amplitude was diminished in T17M <i>RHO</i> CHOP−/− mice at 1 month of age and the values of a-wave amplitudes were 456.3 µv ±39.7 in wild-type; 509.1 µv ±24.9 in CHOP−/−; 169.0 µv ±7.9 in T17M <i>RHO</i>; and 54.4 µv ±16.4 in T17M <i>RHO</i> CHOP−/−. …”

Effect of NaCl on the thermal deactivation prevention ability of <i>M</i>. <i>leprae</i> HSP18. by Sandip Kumar Nandi (713237)

Data_Sheet_1_What Matters Most in Life? A German Cohort Study on the Sources of Meaning and Their Neurobiological Foundations in Four Age Groups.docx by Christopher Karwetzky (11771024)

“…<p>Existing work in the field of positive psychology suggests that people can draw meaning from a variety of sources. The present study aimed to identify the most important sources of meaning and to explore the role of age and neural adaptation processes in this context. …”

Species-specific detection of ectopic cardiac transcription factors in CSCs. by Elisa Belian (750067)

Image_5_Gut Microbiome Signatures Are Biomarkers for Cognitive Impairment in Patients With Ischemic Stroke.TIF by Yi Ling (255394)

SGK1 expression is altered in learned helplessness. by Pawel Licznerski (82554)

“…(B) SGK1 and (C) PSD-95 protein levels in dissected PFC are decreased in the low-escape group. Data are mean ± SEM percent change over control group (naive, <i>n</i> = 5; high escape, <i>n</i> = 5; low escape, <i>n</i> = 9), One-way ANOVA with post hoc Bonferroni test: F(2,16) = 3.373 for SGK1 and F(2,16) = 3.704 for PSD-95, * <i>p</i> < 0.05. …”

Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity by Valentina Noemi Madia (1585285)

“…Most of the designed derivatives were active at micromolar or submicromolar concentration, and the most promising compounds are fluorinated and/or amino acids derivatives <b>13a</b>, <b>14d</b>, and <b>15</b> that showed IC₅₀ 0.16–0.82 μM. …”

Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity by Valentina Noemi Madia (1585285)

“…Most of the designed derivatives were active at micromolar or submicromolar concentration, and the most promising compounds are fluorinated and/or amino acids derivatives <b>13a</b>, <b>14d</b>, and <b>15</b> that showed IC₅₀ 0.16–0.82 μM. …”

Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity by Valentina Noemi Madia (1585285)

“…Most of the designed derivatives were active at micromolar or submicromolar concentration, and the most promising compounds are fluorinated and/or amino acids derivatives <b>13a</b>, <b>14d</b>, and <b>15</b> that showed IC₅₀ 0.16–0.82 μM. …”

Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity by Valentina Noemi Madia (1585285)

“…Most of the designed derivatives were active at micromolar or submicromolar concentration, and the most promising compounds are fluorinated and/or amino acids derivatives <b>13a</b>, <b>14d</b>, and <b>15</b> that showed IC₅₀ 0.16–0.82 μM. …”

Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity by Valentina Noemi Madia (1585285)

“…Most of the designed derivatives were active at micromolar or submicromolar concentration, and the most promising compounds are fluorinated and/or amino acids derivatives <b>13a</b>, <b>14d</b>, and <b>15</b> that showed IC₅₀ 0.16–0.82 μM. …”

Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity by Valentina Noemi Madia (1585285)

“…Most of the designed derivatives were active at micromolar or submicromolar concentration, and the most promising compounds are fluorinated and/or amino acids derivatives <b>13a</b>, <b>14d</b>, and <b>15</b> that showed IC₅₀ 0.16–0.82 μM. …”

miR-182 was expressed in various tissues of dairy goats. by Lei Zhang (38117)

Example of a set of resistance profiles from a system with five strata and four antibiotics. by Sonja Lehtinen (784974)

The effect of STOX1A on cell proliferation in the neuroblastoma cell-line SH-SY5Y. by Daan van Abel (214754)

“…(C) Overexpression and knockdown of STOX1A was determined with quantitative RT-PCR showing a mean 21 fold (mean ΔΔCt 4.4) increase in mRNA expression for STOX1A in stably transfected SH-SH5Y cells compared to the controls (Left bar) and a mean 71 fold (mean ΔΔCt 6.15) decreased mRNA expression for STOX1A siRNA transfected SH-SY5Y cells compared to the scrambled controls (right bar). …”

Inhibition of C5aR signaling and targeted complement inhibition alleviates liver injury. by Shihui Sun (180042)

“…<p>(A–I) Both C5aRmAb and CR2-fH groups displayed reduced liver damage (A–B, D–E, G–H) and decreased C3 deposition (C, F, I) 8 hours after LPS/D-GalN injection. …”

Production of O₂^ꜙ, NO and cyclic GMP by 5-HT. by Marie Billaud (261506)

“…C, as measured by Elisa kit, basal cyclic GMP content (black column) was decreased by 5-HT (white column) whereas it was increased when PEG-SOD and PEG-catalase were added to 5-HT (light grey column). …”

PPM1A is critical for proliferation of intestinal organoids. by Ruyuan Zhou (10197187)

“…A dramatic lower number of de novo crypts (D, top panel) and the decreased size of organoids (D, bottom panel) were seen in organoids from PPM1A KO mice, with roughly 50 intestine organoids each group examined. …”

Table_5_Inflammation produced by senescent osteocytes mediates age-related bone loss.xlsx by Zixuan Wang (35190)

Image_1_IL-6 Receptor Inhibition by Tocilizumab Attenuated Expression of C5a Receptor 1 and 2 in Non-ST-Elevation Myocardial Infarction.TIF by Hilde L. Orrem (5740313)

“…</p><p>Results: Our main findings were (i) Tocilizumab decreased C5aR1 and C5aR2 mRNA expression significantly (p < 0.001) and substantially (>50%) at day 2 and 3, whereas C3aR expression was unaffected. …”