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13181
Image_1_Puerarin Alleviates Vascular Cognitive Impairment in Vascular Dementia Rats.TIF
Published 2021“…Rats with BCCAO developed VD. Pur (50, 100, and 150 mg/kg) dose-dependently attenuated the pathological changes, increased synaptic structural plasticity in the dorsal CA1 hippocampal region and decreased oxidative stress, which eventually reduced cognitive impairment and vascular injury in BCCAO rats. …”
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13182
Table_1_Puerarin Alleviates Vascular Cognitive Impairment in Vascular Dementia Rats.docx
Published 2021“…Rats with BCCAO developed VD. Pur (50, 100, and 150 mg/kg) dose-dependently attenuated the pathological changes, increased synaptic structural plasticity in the dorsal CA1 hippocampal region and decreased oxidative stress, which eventually reduced cognitive impairment and vascular injury in BCCAO rats. …”
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13183
Table_2_Puerarin Alleviates Vascular Cognitive Impairment in Vascular Dementia Rats.xlsx
Published 2021“…Rats with BCCAO developed VD. Pur (50, 100, and 150 mg/kg) dose-dependently attenuated the pathological changes, increased synaptic structural plasticity in the dorsal CA1 hippocampal region and decreased oxidative stress, which eventually reduced cognitive impairment and vascular injury in BCCAO rats. …”
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13184
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13185
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13186
An automated screening method for detecting compounds with goitrogenic activity using transgenic zebrafish embryos
Published 2018“…<div><p>The knowledge on environmentally relevant chemicals that may interfere with thyroid signaling is scarce. Here, we present a method for the screening of goitrogens, compounds that disrupt the thyroid gland function, based on the automatic orientation of zebrafish in a glass capillary and a subsequent imaging of reporter gene fluorescence in the thyroid gland of embryos of the transgenic zebrafish line tg(tg:mCherry). …”
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13187
Photoreceptors undergo substantial changes in TF activity during aging.
Published 2022“…<p>A. Heatmap of RNA-seq fold change during aging for significantly differentially expressed genes (DEGs; p-adj<0.05, |FC|>1.5 relative to D10) associated with the GO term “RNA polymerase II-specific DNA-binding transcription factor binding” (GO:0061629). …”
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13188
Self-Powered TENG with High Humidity Sensitivity from PVA Film Modified by LiCl and MXene
Published 2023“…Short-circuit current of the TENG in a wide range of RH (from 50% to 98%) responds very sensitively to humidity fluctuations in the environment and superior adsorption–desorption performance as humidity decreases. …”
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13189
Self-Powered TENG with High Humidity Sensitivity from PVA Film Modified by LiCl and MXene
Published 2023“…Short-circuit current of the TENG in a wide range of RH (from 50% to 98%) responds very sensitively to humidity fluctuations in the environment and superior adsorption–desorption performance as humidity decreases. …”
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13190
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13191
Salicylic Acid Derivatives Inhibit Oxalate Production in Mouse Hepatocytes with Primary Hyperoxaluria Type 1
Published 2018“…We introduce here an unprecedented activity of salicylic acid derivatives as agents capable of decreasing oxalate output in hyperoxaluric hepatocytes at the low micromolar range, which means a potential use in the treatment of PH1. …”
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13192
Salicylic Acid Derivatives Inhibit Oxalate Production in Mouse Hepatocytes with Primary Hyperoxaluria Type 1
Published 2018“…We introduce here an unprecedented activity of salicylic acid derivatives as agents capable of decreasing oxalate output in hyperoxaluric hepatocytes at the low micromolar range, which means a potential use in the treatment of PH1. …”
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13193
Potency and breadth of subject immune sera.
Published 2020“…The plot for each serum shows the proportion of viruses neutralized by FRNT<sub>50</sub> at a given serum dilution. Each step in each plot represents an FRNT<sub>50</sub> value for one virus; as fold serum dilution increases for each serum, the proportion of viruses neutralized decreases by 1/11 (9.1%) as each FRNT<sub>50</sub> dilution for each virus is crossed. …”
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13194
Potent Half-Sandwich Iridium(III) Anticancer Complexes Containing C<sup>∧</sup>N‑Chelated and Pyridine Ligands
Published 2015“…The monodentate py ligands blocked hydrolysis; however, antiproliferative studies showed that all the Ir compounds are highly active toward A2780, A549, and MCF-7 human cancer cells. In general the introduction of an electron-donating group (e.g., Me, NMe<sub>2</sub>) at specific positions on the pyridine ring resulted in increased antiproliferative activity, whereas electron-withdrawing groups (e.g., COMe, COOMe, CONEt<sub>2</sub>) decreased anticancer activity. …”
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13195
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13196
Transgenerational hormetic effects of sublethal dose of flupyradifurone on the green peach aphid, <i>Myzus persicae</i> (Sulzer) (Hemiptera: Aphididae)
Published 2019“…<i>persicae</i> with a 48 h LC<sub>50</sub> of 8.491 mg/L. Using the age-stage two-sex life table approach, we assessed the effects of LC<sub>25</sub> of flupyradifurone on adult <i>M</i>. …”
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13197
5‑Aroylindoles Act as Selective Histone Deacetylase 6 Inhibitors Ameliorating Alzheimer’s Disease Phenotypes
Published 2018“…<i>N</i>-Hydroxy-4-((5-(4-methoxybenzoyl)-1<i>H</i>-indol-1-yl)methyl)benzamide (<b>6</b>) has potent inhibitory selectivity against histone deacetylase 6 (HDAC6) with an IC<sub>50</sub> value of 3.92 nM. It decreases not only the level of phosphorylation of tau proteins but also the aggregation of tau proteins. …”
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13198
Effects of Sediment Characteristics on the Toxicity of Chromium(III) and Chromium(VI) to the Amphipod, <i>Hyalella azteca</i>
Published 2004“…Waterborne Cr(VI) caused reduced survival of amphipods with a median lethal concentration (LC<sub>50</sub>) of 40 μg/L. …”
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13200