SENP5 knockdown antagonizes the effect of TPEN on apoptosis and induced abnormal differentiation of hiPSCs. by Xiaoyu Zhang (62901)

“…TPEN (10 μM) significantly decreased hiPSC-CM viability, which was abrogated by siSENP5 (n = 6). …”

The significant immune escape of pseudotyped SARS-CoV-2 variant Omicron by Li Zhang (8200)

“…Our results indicated that the mean neutralization ED50 of these sera against Omicron decreased to 66, which is about 8.4-folds compared to the D614G reference strain (ED50 = 556), whereas the neutralization activity of other VOC and VOI pseudotyped viruses decreased only about 1.2–4.5-folds. …”

Identification and comparison of heart-rate dynamics during cycle ergometer and treadmill exercise by Kenneth J. Hunt (7300430)

“…An observed moderate level of evidence that root-mean-square model error was higher for the CE than for the TM (2.5 bpm ± 0.5 bpm vs. 2.2 bpm ± 0.5 bpm, <i>p</i> = 0.059) may reflect a decrease in heart rate variability with increasing HR intensity because, in order to achieve similar levels of perceived intensity, mean heart rate for the CE was ∼25 bpm lower than for the TM.…”

Skn-1a is required for the functional differentiation of Trpm5-positive tracheal brush cells. by Junpei Yamashita (2583877)

“…The signals of Trpm5 were completely absent in the <i>Skn-1a</i>-/- tracheal epithelium, and the number of villin-single positive cells was significantly decreased in <i>Skn-1a</i>-/- mice. …”

MakA contributes to host cell toxicity. by Aftab Nadeem (3211719)

“…(C) PA:PC liposomes were treated with vehicle (Tris 20mM) or MakA (50μg/mL) for 90 min and stained with 1.5% uranyl acetate solution. …”

Interactions between sward heights of Kikuyu grass and time of day and period of evaluation. by Alejandra Marín Gómez (13020659)

Linear mixed effect model comparing spike exposure groups in a nursing home cohort—Georgia, December 2020–July 2022, n = 37. by Zeshan A. Chisty (18388200)

List of selected metabolites that associate with diabetes at q-values <0.05 using log-scaled metabolite concentrations and assuming a linear model; %change is the increase or decre... by Karsten Suhre (67967)

FGF18 injections increase cartilage thickness, chondrocyte proliferation and induce healing after TMJ experimental degeneration. by Flavia Gomes Velasque Gama (21175112)

Motor neurons in the cervical spinal cord of G93A mice at early and late stage of disease (cresyl violet staining). by Svitlana Garbuzova-Davis (81764)

“…In G93A mice, numerous motor neurons with vacuolization (asterisks) were found at (C) 13 weeks of age and (D) decreased numbers of motor neurons were noted in 17–18 week old mice. …”

Mean histopathological severity scores in control, paraquat and MPTP-treated groups of C57BL/6J male mice. by Richard Jay Smeyne (3278886)

“…Serial sections through the SNpc were evaluated qualitatively and the group mean severity grades are plotted. Grades 0 to 5 reflect increasing intensity of staining for Iba-1, AmCuGg, GFAP and decreased staining intensity of TH.…”

FGF18 injections increase chondroprogenitors and extracellular matrix and reduce chondrocyte hypertrophy after TMJ experimental degeneration. by Flavia Gomes Velasque Gama (21175112)

Pre-incubation of SB105-A10 either with HIV-1_IIIb or HIV-1_ada strains inhibits the viral infectivity in dilution assay. by Isabella Bon (467395)

“…<p>HIV-1 strains were incubated for 1 hour at 37°C with SB105-A10 (20 µg/ml; 4.2 µM). Following this incubation the samples were diluted 50-fold to reduce dendrimer concentrations to a level below that at which SB105-A10 significantly inhibits HIV replication and challenged with activated PBMCs. …”

NB polarity and number are unaffected by knockdown of mitochondrial morphology proteins. by Dnyanesh Dubal (12085942)

Supplementary Material for: Association of platelet count and mean platelet volume with fish intake frequency: Implication for the cardioprotective effect of fish intake by figshare admin karger (2628495)

“…Introduction: Mean platelet volume (MPV) measures platelet activity, and high values indicate increased atherosclerotic cardiovascular disease (ASCVD) risk. …”

Dehydrozingerone Improves Mood and Memory in Diabetic Mice via Modulating Core Neuroimmune Genes and Their Associated Proteins by Anuradha Kesharwani (21386000)

“…Additionally, anomalies in the glutamine-glutamate/GABA cycle could exacerbate diabetes-related cognitive deficits. Treatment with DH had a variety of advantages, including decreased neuroinflammation and neuronal cell death as well as the promotion of critical genes and proteins necessary to promote cognitive performance. …”

Illustration of household-based strategy. by Callum Shaw (15628313)

Excel spreadsheet containing, in separate sheets, the underlying numerical data and statistical analysis for Figs 1–7 and all supplemental figures. by Brandon F. Keele (7450001)

Household-based strategy with single household member testing. by Callum Shaw (15628313)

The Sulfamate Small Molecule CAIX Inhibitor S4 Modulates Doxorubicin Efficacy by Simon J. A. van Kuijk (2938218)

“…<div><p>Carbonic anhydrase IX (CAIX) is a tumor-specific protein that is upregulated during hypoxic conditions where it is involved in maintaining the pH balance. …”