Loss of Vps34 reduces Treg suppressive function and is associated with the development of type-I-dominant inflammatory disease. by Erienne G. Norton (9612079)

Video1_Case Report: Three-dimensional printed prosthesis reconstruction for patello-femoral large osteochondral defects in a patient with distal femoral giant cell tumour: A case r... by Dechao Yuan (12995895)

“…At the last follow-up 27 months after surgery, she was pain free, the Musculoskeletal Tumour Society (MSTS) score improved from 15/30 to 29/30, the Visual Analogue Scale (VAS) score decreased from 7 to 0, and knee flexion increased from 50° to 130°. …”

<i>B</i>. <i>longum</i> BORI (<i>B</i>. BORI) reduces bone and cartilage erosion in MIA-induced OA rats. by Dong Keon Oh (16436697)

Key inputs in the model. by Jie Pan (187977)

“…Consequently, a scenario analysis based on subgroups of Chinese females was conducted for this study. …”

Table_1_A Meta-Analysis of the Effects of Foam Rolling on Performance and Recovery.pdf by Thimo Wiewelhove (804514)

“…The objective of this meta-analysis was to compare the effects of foam rolling applied before (pre-rolling as a warm-up activity) and after (post-rolling as a recovery strategy) exercise on sprint, jump, and strength performance as well as on flexibility and muscle pain outcomes and to identify whether self-massage with a foam roller or a roller massager is more effective. …”

Table_2_A Meta-Analysis of the Effects of Foam Rolling on Performance and Recovery.pdf by Thimo Wiewelhove (804514)

“…The objective of this meta-analysis was to compare the effects of foam rolling applied before (pre-rolling as a warm-up activity) and after (post-rolling as a recovery strategy) exercise on sprint, jump, and strength performance as well as on flexibility and muscle pain outcomes and to identify whether self-massage with a foam roller or a roller massager is more effective. …”

Vps34 orchestrates Treg function in vivo. by Erienne G. Norton (9612079)

Peptides of AnxA2 R1 domain interfere with the PCSK9≡LDLR interaction. by Nabil G. Seidah (148050)

“…The AlphaScreen luminescence signal was measured at 580 nm emission wavelength. The competition of AnxA2 peptides with the PCSK9≡LDLR interaction was revealed by a decrease in luminescence signal and demonstrated that the longest AnxA2 peptide (aa 25–97) inhibits binding of PCSK9 to LDLR with an IC₅₀ of 0.6 µM. …”

Development-specific <i>cyc</i> downregulation in <i>Pdf</i>+ cells prevents sLN_v fasciculation. by Grace Biondi (19924067)

The orientation of the <i>pdcC</i> switch controls <i>pdcC</i> expression. by Leila M. Reyes Ruiz (6690206)

Tryptophan end-tagging confers antifungal activity to a tick-derived antimicrobial peptide by Court Chiramba (19114972)

“…Although reduced, Os-C(W₅) retains some antibiofilm activity in RPMI-1640 supplemented with 50% foetal bovine serum and in a synthetic wound medium.…”

Depletion of <i>Tg</i>RPI results in severe growth defects <i>in vitro</i> and <i>in vivo</i>. by Ningbo Xia (13584299)

Vps34 is essential for terminal differentiation of eTregs during perinatal life. by Erienne G. Norton (9612079)

“…(<b>F</b>) GSEA enrichment plots showing increased Vps34-activated signature (upper; i.e., top 200 downregulated genes [log₂FC < −0.5, <i>P</i> < 0.05]) in Vps34-deficient Tregs versus control Tregs from mixed BM chimeras; see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003074#pbio.3003074.s010" target="_blank">S2 Table</a> and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003074#sec010" target="_blank">Materials and methods</a> for details) and decreased Vps34-suppressed signature (lower; i.e., top 200 upregulated genes [log₂FC > 0.5, <i>P</i> < 0.05]) in Vps34-deficient Tregs versus control Tregs from mixed BM chimeras; see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003074#pbio.3003074.s010" target="_blank">S2 Table</a> and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003074#sec010" target="_blank">Materials and methods</a> for details) in KLRG1⁺Nfil3⁺ terminal Tregs compared to KLRG1⁻Nfil3⁺ transitional Tregs (from a public RNA-seq dataset GSE130884 [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003074#pbio.3003074.ref011" target="_blank">11</a>]; see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003074#sec010" target="_blank">Materials and methods</a> for details). …”

Subclinical Left Atrial and Ventricular Dysfunction in Acromegaly Patients: A Speckle Tracking Echocardiography Study by Hasan Koca (10375963)

Diastolic Left Ventricular Function in Relation to Urinary and Serum Collagen Biomarkers in a General Population by Zhen-Yu Zhang (458621)

“…We randomly recruited 782 Flemish (51.3% women; 50.5 years). We assessed diastolic LV function from the early and late diastolic peak velocities of the transmitral blood flow and of the mitral annulus. …”

DataSheet_1_Increased IL-26 associates with markers of hyperinflammation and tissue damage in patients with acute COVID-19.docx by Eduardo I. Cardenas (12409006)

Severity of anaemia status among pregnant women. by Donatus Nbonibe Abaane (15909683)

“…At 36 weeks, AIP prevalence was 44.8% (95%CI:39.2, 50.4) using a cut-off of 11.0g/dl. At p<0.05, registering after the first trimester (AOR = 1.87, 95%CI: 1.17, 2.98, P = 0.009) and at a regional hospital (AOR = 2.25, 95%CI: 1.02, 4.98, P = 0.044) were associated with increased odds of AIP but registering at a private hospital (AOR = 0.32, 95%CI: 0.11, 0.92, P = 0.035) was associated with decreased odds of AIP at booking. …”

Effects of bortezomib on OATP1B1-mediated [³H]pitavastatin and [³H]E₂17βG transport in HEK293-OATP1B1 cells and on [³H]pitavastatin accu... by Khondoker Alam (1443499)

(A) Schematic presentation of the human AID protein sequence along with the positions of the lysine residues mutated in the various constructs by Said Aoufouchi (49316)

“…(D) Stable BL2 clones expressing the indicated AID-EGFP lysine mutants, WT-AID-EGFP, or mutNLS-AID-EGFP were incubated with cycloheximide (CHX, 50 μg/ml) and LMB (10 ng/ml). The decay of the protein was followed by the decrease in fluorescence intensity. …”

Photomicrographs of prostate sections stained with H&E and toluidine blue. by Rabab Ahmed Rasheed (12536918)