Showing 301 - 320 results of 29,203 for search '(( 50 ((nn decrease) OR (a decrease)) ) OR ( 5 ((nm decrease) OR (teer decrease)) ))', query time: 0.76s Refine Results
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    Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors by Stanislav Andreev (11067165)

    Published 2021
    “…Surprisingly, our results demonstrate that this high-energy water was not displaced by our potent inhibitor (<i>S</i>)-3-(3-((7-ethynyl-9<i>H</i>-pyrimido­[4,5-<i>b</i>]­indol-4-yl)­(methyl)­amino)­piperidin-1-yl)­propanenitrile (<b>(<i>S</i>)</b>-<b>15</b>, IC<sub>50</sub> value of 6 nM). …”
  5. 305

    Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors by Stanislav Andreev (11067165)

    Published 2021
    “…Surprisingly, our results demonstrate that this high-energy water was not displaced by our potent inhibitor (<i>S</i>)-3-(3-((7-ethynyl-9<i>H</i>-pyrimido­[4,5-<i>b</i>]­indol-4-yl)­(methyl)­amino)­piperidin-1-yl)­propanenitrile (<b>(<i>S</i>)</b>-<b>15</b>, IC<sub>50</sub> value of 6 nM). …”
  6. 306

    Effects of intracellular treatment with 5- or 40-nm AuNPs on AP properties in hippocampal CA1 neurons. by Seungmoon Jung (534987)

    Published 2014
    “…<p>(A) AuNPs of both sizes significantly decreased the latency to the first AP. The 40-nm AuNPs significantly reduced the AP threshold (B) and AP duration (C). …”
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    KYNA and zaprinast decrease the [Ca<sup>2+</sup>]i plateau phase following an IP3-mediated stimulus in mouse cortical astrocytes. by Rolando Berlinguer-Palmini (491113)

    Published 2013
    “…<b>E</b>) Time course of MRS-1845, D-APV (50 µM) and MLA (100 nM) effects on fluo-3 fluorescence in a single astrocyte in cultures. …”
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