B-Raf^V600E melanoma cells acquire cancer phenotypes partly by increasing the expression levels of miR-10b. by Ila Datar (433874)

“…<p>(a) Upper panel: B-Raf^V600E knockdown decreases number of colonies in soft agar in sk-mel-28 cell line. …”

Dramatic Lockdown Fossil Fuel CO₂ Decrease Detected by Citizen Science-Supported Atmospheric Radiocarbon Observations by Jocelyn C. Turnbull (6083705)

“…This is consistent with sparse local traffic count information and a much larger decrease in traffic emissions than reported in global aggregate estimates of emission changes. …”

Relative <i>CHRNA5</i> promoter activity in BE(2)-C cells. by Glenn A. Doyle (209929)

“…The deletion (“d” in construct name) or normal (“i” in construct name) allele at rs3841324 is indicated by a red triangle or blue square, respectively. The deletion (“d”) constructs exhibited decreased activity (1.6–2.0-fold) relative to the normal (“i”) constructs. …”

LOH unlinks 189R/R from a stop codon with masking effects on phenotype. by Pétra Vande Zande (17628246)

Image_5_Optimization of ATP Synthase c–Rings for Oxygenic Photosynthesis.tiff by Geoffry A. Davis (4232317)

Image_5_Optimization of ATP Synthase c–Rings for Oxygenic Photosynthesis.tiff by Geoffry A. Davis (4232317)

Auxiliary proteins may act as rate-limiting factors of the m6A writer complex. by Kiran Pandey (9282593)

“…<p>Here we use the term ‘rate-limiting’ to describe the functionally limiting component, based on knockdown correlations rather than direct kinetic measurements. About 50% of m6A remained when METTL3 was reduced to 5%, showing that only a small amount of METTL3 is required to maintain physiological levels of m6A in mRNA. …”

Consequences of global and local c-di-GMP changes on <i>V</i>. by Andrew A. Bridges (1587328)

“…Samples were collected at OD₆₀₀ = 0.1, complete datasets are available in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3001585#pbio.3001585.s011" target="_blank">S1 Data</a>, and volcano plots for each condition are shown in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3001585#pbio.3001585.s004" target="_blank">S4 Fig</a>. …”

Analgesic prescriptions received by patients before commencing the BOA model of care for osteoarthritis: a Swedish national registry study with matched reference and clinical guide... by Allan Abbott (6032138)

“…Since guideline publication, the proportion of the OA cohort having no dispensed prescription analgesics prior to non-pharmacological primary care intervention concordantly increased by 5.0% (95% CI 4.2–5.9). Furthermore, dispensed prescriptions concordantly decreased for non-selective NSAIDs –8.6% (CI –9.6 to –7.6), weak opioids –6.8% (CI –7.7 to –5.9), glucosamine –9.5% (CI –9.8 to –8.8). and hyaluronic acid –1.6% (CI –1.8 to –1.5) but discordantly increased for strong opioids 2.8% (CI 2.1–3.4) and glucocorticoid intra-articular injection for hip OA 2.1% (CI 1.0–3.1).…”

Decreased dendritic spine density and mEPSC amplitude in the DG of Arf4^+/− mice compared to WT mice. by Sachi Jain (108277)

Long-noncoding RNA HOXA transcript at the distal tip ameliorates the insulin resistance and hepatic gluconeogenesis in mice with gestational diabetes mellitus via the microRNA-423-... by Qianqian Cao (7309022)

“…The relations among HOTTIP, miR-423-5p and WNT7A were validated. HOTTIP and WNT7A levels were decreased while miR-423-5p was elevated in GDM mice. …”

Exendin–4 and metformin decrease the number of Ki67 and P504S-positive cells, and increase GLP-1R expression. by Yoko Tsutsumi (803696)

Critical role of miR-10b in B-Raf^V600E dependent anchorage independent growth and invasion of melanoma cells by Ila Datar (433874)

“…We observed that miR-10b expression correlates with the presence of the oncogenic <i>B-Raf</i> (<i>B-Raf</i>^<i>V600E</i>) mutation in melanoma cells. While expression of miR-10b enhances anchorage-independent growth of <i>B-Raf</i> wild-type melanoma cells, miR-10b silencing decreases <i>B-Raf</i>^<i>V600E</i> cancer cell invasion <i>in vitro</i>. …”

SS-31 treatment reduced ox-LDL-induced lipid accumulation in peritoneal derived macrophages, associated with decreased lipid influx. by Meng Zhang (154027)

Decrease of Population Divergence in Eurasian Perch (<i>Perca fluviatilis</i>) in Browning Waters: Role of Fatty Acids and Foraging Efficiency by Kristin Scharnweber (2742514)

“…We expected a decrease in the prevalence of PUFAs, which are important for perch growth and divergence with increasing DOC concentrations, due to the restructuring effects of DOC on aquatic food webs. …”

Anti-influenza A virus activity of rhein through regulating oxidative stress, TLR4, Akt, MAPK, and NF-κB signal pathways - Fig 4 by Qian-Wen Wang (3467420)

Comparing A) ROS and B) GSH levels in COCs versus DOs recovered from PMSG-stimulated NMRI mice cultured in absence or presence of 0.5 µM PA during IVM. Data are presented as means... by Shahrzad Ronasi (20933556)

Image_1_Quantitative Proteome Profiling of a S-Nitrosoglutathione Reductase (GSNOR) Null Mutant Reveals a New Class of Enzymes Involved in Nitric Oxide Homeostasis in Plants.TIF by Patrick Treffon (11815754)

“…Here, we performed a proteomic analysis examining changes in the total leaf proteome of an Arabidopsis thaliana GSNOR null mutant (hot5-2/gsnor1-3). …”

Table_1_Quantitative Proteome Profiling of a S-Nitrosoglutathione Reductase (GSNOR) Null Mutant Reveals a New Class of Enzymes Involved in Nitric Oxide Homeostasis in Plants.pdf by Patrick Treffon (11815754)

“…Here, we performed a proteomic analysis examining changes in the total leaf proteome of an Arabidopsis thaliana GSNOR null mutant (hot5-2/gsnor1-3). …”

Data_Sheet_1_Quantitative Proteome Profiling of a S-Nitrosoglutathione Reductase (GSNOR) Null Mutant Reveals a New Class of Enzymes Involved in Nitric Oxide Homeostasis in Plants.X... by Patrick Treffon (11815754)

“…Here, we performed a proteomic analysis examining changes in the total leaf proteome of an Arabidopsis thaliana GSNOR null mutant (hot5-2/gsnor1-3). …”