Image6_Effect of Rumex dentatus on Gastrointestinal Protection and Toxicology in Rodents via Investigating H+/K+-ATPase, Calcium Channels, and PDE Mediated Signaling.tiff by Neelam Gul Qazi (13178827)

“…Extracts and emodin also show an inhibitory effect against H⁺/K⁺-ATPase. Rumex dentatus showed a gastroprotective and antioxidant effect. Histopathological evaluation showed improvement in cellular architecture and decrease in the expression of inflammatory markers such as cyclooxygenase (COX2), tumor necrosis factor (TNF-α), and phosphorylated nuclear factor kappa B (p-NFƙB), validated through immunohistochemistry, ELISA, and western blot techniques. …”

Table5_Effect of Rumex dentatus on Gastrointestinal Protection and Toxicology in Rodents via Investigating H+/K+-ATPase, Calcium Channels, and PDE Mediated Signaling.docx by Neelam Gul Qazi (13178827)

“…Extracts and emodin also show an inhibitory effect against H⁺/K⁺-ATPase. Rumex dentatus showed a gastroprotective and antioxidant effect. Histopathological evaluation showed improvement in cellular architecture and decrease in the expression of inflammatory markers such as cyclooxygenase (COX2), tumor necrosis factor (TNF-α), and phosphorylated nuclear factor kappa B (p-NFƙB), validated through immunohistochemistry, ELISA, and western blot techniques. …”

Table6_Effect of Rumex dentatus on Gastrointestinal Protection and Toxicology in Rodents via Investigating H+/K+-ATPase, Calcium Channels, and PDE Mediated Signaling.docx by Neelam Gul Qazi (13178827)

“…Extracts and emodin also show an inhibitory effect against H⁺/K⁺-ATPase. Rumex dentatus showed a gastroprotective and antioxidant effect. Histopathological evaluation showed improvement in cellular architecture and decrease in the expression of inflammatory markers such as cyclooxygenase (COX2), tumor necrosis factor (TNF-α), and phosphorylated nuclear factor kappa B (p-NFƙB), validated through immunohistochemistry, ELISA, and western blot techniques. …”

Table4_Effect of Rumex dentatus on Gastrointestinal Protection and Toxicology in Rodents via Investigating H+/K+-ATPase, Calcium Channels, and PDE Mediated Signaling.docx by Neelam Gul Qazi (13178827)

“…Extracts and emodin also show an inhibitory effect against H⁺/K⁺-ATPase. Rumex dentatus showed a gastroprotective and antioxidant effect. Histopathological evaluation showed improvement in cellular architecture and decrease in the expression of inflammatory markers such as cyclooxygenase (COX2), tumor necrosis factor (TNF-α), and phosphorylated nuclear factor kappa B (p-NFƙB), validated through immunohistochemistry, ELISA, and western blot techniques. …”

Data Sheet 1_Virological response and predictive factors for antiviral treatment in chronic HBV-related liver disease with low ALT and high HBV DNA.docx by Lei Ma (221178)

“…The low-HBV DNA (82.46% (47/57)) and high-APRI subgroup (63.79% (37/58)) had higher CVR rates than the high-HBV DNA (7.84% (4/51)) and low-APRI subgroup (28% (14/50)) respectively. High HBV DNA and low ALT patients in NG had a CVR of 0% (0/18). …”

Table3_Effect of Rumex dentatus on Gastrointestinal Protection and Toxicology in Rodents via Investigating H+/K+-ATPase, Calcium Channels, and PDE Mediated Signaling.docx by Neelam Gul Qazi (13178827)

“…Extracts and emodin also show an inhibitory effect against H⁺/K⁺-ATPase. Rumex dentatus showed a gastroprotective and antioxidant effect. Histopathological evaluation showed improvement in cellular architecture and decrease in the expression of inflammatory markers such as cyclooxygenase (COX2), tumor necrosis factor (TNF-α), and phosphorylated nuclear factor kappa B (p-NFƙB), validated through immunohistochemistry, ELISA, and western blot techniques. …”

Image4_Effect of Rumex dentatus on Gastrointestinal Protection and Toxicology in Rodents via Investigating H+/K+-ATPase, Calcium Channels, and PDE Mediated Signaling.tiff by Neelam Gul Qazi (13178827)

“…Extracts and emodin also show an inhibitory effect against H⁺/K⁺-ATPase. Rumex dentatus showed a gastroprotective and antioxidant effect. Histopathological evaluation showed improvement in cellular architecture and decrease in the expression of inflammatory markers such as cyclooxygenase (COX2), tumor necrosis factor (TNF-α), and phosphorylated nuclear factor kappa B (p-NFƙB), validated through immunohistochemistry, ELISA, and western blot techniques. …”

IGF1 induces alveolar morphogenesis and expression of target genes in prenatal lungs cultured <i>ex vivo</i>. by Rosete Sofía Pais (504295)

“…Scale bar corresponds to 500 µm in A–D; 50 µm in E–H, and 7 µm in their insets; 20 µm in I–L.…”

Image3_Effect of Rumex dentatus on Gastrointestinal Protection and Toxicology in Rodents via Investigating H+/K+-ATPase, Calcium Channels, and PDE Mediated Signaling.tiff by Neelam Gul Qazi (13178827)

“…Extracts and emodin also show an inhibitory effect against H⁺/K⁺-ATPase. Rumex dentatus showed a gastroprotective and antioxidant effect. Histopathological evaluation showed improvement in cellular architecture and decrease in the expression of inflammatory markers such as cyclooxygenase (COX2), tumor necrosis factor (TNF-α), and phosphorylated nuclear factor kappa B (p-NFƙB), validated through immunohistochemistry, ELISA, and western blot techniques. …”

Data_Sheet_1_Organic-Inorganic Hybrid Planarization and Water Vapor Barrier Coatings on Cellulose Nanofibrils Substrates.docx by Feyza Karasu (1909087)

“…However, the permeability of such materials to oxygen and water vapor is very sensitive to moisture, which limits their potential for a variety of packaging and encapsulation applications. …”

Glutamate accelerates synaptic release from cone terminals. by Skyler L. Jackman (222281)

“…(C) Time-course of FM1-43 fluorescence decreases from cone terminals in darkness (<i>n</i> = 27, error bars are obscured by the data points) and 2 mM glutamate (<i>n</i> = 5). …”

Image1_DNA aptamer-functionalized PDA nanoparticles: from colloidal chemistry to biosensor applications.pdf by Ohnmar Zaw (18994019)

“…PDA NPs were synthesized by the oxidation of dopamine in Tris buffer at pH 10.5, conjugated with DNA aptamers specific to GA at different concentrations (0.05, 0.5, and 5 μM), and deposited on screen-printed carbon electrodes (SPCEs). …”

TRα2 shows dominant negative activity on positively and negatively regulated T₃ target genes <i>in vivo</i>. by Hajer Guissouma (586934)

“…</b><i>ME-tk-luc</i> transcription was measured in hypothyroid (PTU) 2 days old mice treated with T₃ (2.5 µg/g b.w.) (PTU+T3) or saline (PTU), 18 h after hypothalamic injection of 1 µg reporter construct and 100 ng expression vector (empty pSG5 (Ct) or pSG5-TRα1 (TRα1) or pSG5-TRα2 (TRα2)). …”

Elimination of Schistosomiasis Transmission in Zanzibar: Baseline Findings before the Onset of a Randomized Intervention Trial by Stefanie Knopp (108848)

“…</p><p>Principal Findings</p><p>The baseline <i>Schistosoma haematobium</i> prevalence in school children and adults was 4.3% (range: 0–19.7%) and 2.7% (range: 0–26.5%) in Unguja, and 8.9% (range: 0–31.8%) and 5.5% (range: 0–23.4%) in Pemba, respectively. …”

DataSheet1_Generation and characterization of a novel gne Knockout Model in Zebrafish.docx by Hagay Livne (13999902)

“…To have deeper insights into the potential functions of gne in zebrafish, RNA sequencing was performed at 3 time points (3, 5, and 7 dpf). Genotype clustering was progressive, with only 5 genes differentially expressed in gne KO compared to gne WT siblings at 3 dpf. …”

Chromosomal microdeletions contribute to mitochondrial respiratory chain complex deficiencies. by Masakazu Kohda (206767)

“…Compared with TurboRFP-V5 expressing Pt657 fibroblasts, expression of wild-type COX10-V5 in Pt657 fibroblasts resulted in a significant increase in complex IV activity (<b>G</b>).…”

Mucosa-associated bacterial microbiota profiling. by Martinna Bertolini (6619808)

“…G: Identification of bacteria isolated from the tongues of mice after 8 days of receiving 5Fu and <i>C</i>. <i>albicans</i> SC5314. The V4 variable region of the 16S rDNA gene was amplified and sequenced by Illumina. 98% of the OTU sequences from five isolates aligned with the genus <i>Enterococcus</i>. …”

EHEC-Hly-containing OMVs are internalized via dynamin-dependent endocytosis. by Martina Bielaszewska (79970)

“…Nuclei were stained with DRAQ5 (blue). Pictures were taken using a laser-scanning microscope (LSM 510 META microscope equipped with a Plan-Apochromat 63x/1.4 oil immersion objective). …”

Deficiencies of TWEAK attenuate NF-ĸB2 activation in the RNA toxicity mice. by Ramesh S. Yadava (2268922)

“…(C) Quantification of western blots for NF-κB2 shows that p52 levels in TWEAK deficient RNA toxicity mice (DM5/<i>Tweak</i>^<i>-/-</i> D+) was decreased significantly as compared to RNA toxicity mice wildtype for <i>Tweak</i> (DM5/<i>Tweak</i>^<i>-+/+</i> D+). n = 4 per group used for analysis; error bars are mean ± s.e.m.; (*p = 0.05 (Student’s t test)).…”

Figure 2 from Auranofin Synergizes with Cisplatin in Reducing Tumor Burden of NOTCH-Dependent Ovarian Cancer by Robert J. Lake (22408833)

“…RBPJ occupancy at <i>HES1</i> and <i>HES4</i> promoters decreased in a dose-dependent manner. <i>CDKN1A</i> (p21) served as a negative control. …”