Distribution of heroin and its metabolites in plasma and brain after i.v. infusion of 0.125 or 0.0625 mg/kg heroin. by Michael D. Raleigh (678771)

“…Plasma (B) and brain (C) opioid concentrations (mean ± SD) after the 8^th infusion of 0.125 or 0.0625 mg/kg heroin (cumulative doses of 1.0 and 0.5 mg/kg heroin, respectively). …”

Table 5_Preliminary study on the time-correlation changes in brain neurotransmitters of mice exposed to mushroom toxin ibotenic acid.docx by Ruanxian Dai (21460028)

“…</p>Objective<p>This study aims to systematically evaluate the effects of ibotenic acid exposure across three consecutive key time points, from intoxication to recovery, on neurotransmitters related to the GABA/Glutamic-Acid, dopaminergic, serotonergic, and cholinergic systems in five brain regions: the cerebral cortex, hippocampus, striatum, brain stem, and cerebellum.…”

Inhibition of CFTR Cl^¯ channels by fractions from <i>Rhodiola kirilowii</i> (Regel) Maxim. by Lei Chen (54296)

A Coordination Chemistry Study of Hydrated and Solvated Cationic Vanadium Ions in Oxidation States +III, +IV, and +V in Solution and Solid State by Joanna Krakowiak (1288782)

“…In the DMPU-solvated oxovanadium­(IV) ion, the space-demanding properties of the DMPU molecule leave no solvent molecule in the trans position to the oxo group, which reduces the coordination number to 5. The OVO bond angle is consequently much larger, 107°, and the mean VO and V–O bond distances decrease to 1.58 and 1.97 Å, respectively. …”

Transepithelial sodium current measurements of Cohort 3 (upper graph) and Cohort 4 (middle graph) and Cohort 5 (lower graph). by Andrew Resnick (340899)

“…The monolayers in Cohort 3 show a response to the presence (points 3B and 3C) or absence (points 3A) of apical fluid flow only, while the monolayers in Cohort 4 and 5 show a graded response to apical fluid flow. …”

Image_5_Converging and Differential Brain Phospholipid Dysregulation in the Pathogenesis of Repetitive Mild Traumatic Brain Injury and Alzheimer’s Disease.JPEG by Joseph O. Ojo (5539157)

An automated screening method for detecting compounds with goitrogenic activity using transgenic zebrafish embryos by Sergio Jarque (5698859)

“…<div><p>The knowledge on environmentally relevant chemicals that may interfere with thyroid signaling is scarce. Here, we present a method for the screening of goitrogens, compounds that disrupt the thyroid gland function, based on the automatic orientation of zebrafish in a glass capillary and a subsequent imaging of reporter gene fluorescence in the thyroid gland of embryos of the transgenic zebrafish line tg(tg:mCherry). …”

Table_1_Modulatory effect of filarial infection on the systemic hormone levels in subjects with metabolic syndrome (DM-LF5).xlsx by Joy Manohar Sibi (11416880)

Presentation_1_Modulatory effect of filarial infection on the systemic hormone levels in subjects with metabolic syndrome (DM-LF5).ppt by Joy Manohar Sibi (11416880)

Electrical impedance cole parameters. by W. David Arnold (3373874)

Salicylic Acid Derivatives Inhibit Oxalate Production in Mouse Hepatocytes with Primary Hyperoxaluria Type 1 by María Dolores Moya-Garzón (5597540)

“…We introduce here an unprecedented activity of salicylic acid derivatives as agents capable of decreasing oxalate output in hyperoxaluric hepatocytes at the low micromolar range, which means a potential use in the treatment of PH1. …”

Salicylic Acid Derivatives Inhibit Oxalate Production in Mouse Hepatocytes with Primary Hyperoxaluria Type 1 by María Dolores Moya-Garzón (5597540)

“…We introduce here an unprecedented activity of salicylic acid derivatives as agents capable of decreasing oxalate output in hyperoxaluric hepatocytes at the low micromolar range, which means a potential use in the treatment of PH1. …”

Potency and breadth of subject immune sera. by Chad D. Nix (8704143)

“…The plot for each serum shows the proportion of viruses neutralized by FRNT₅₀ at a given serum dilution. Each step in each plot represents an FRNT₅₀ value for one virus; as fold serum dilution increases for each serum, the proportion of viruses neutralized decreases by 1/11 (9.1%) as each FRNT₅₀ dilution for each virus is crossed. …”

Image_5_Elucidating the changes in the heterogeneity and function of radiation-induced cardiac macrophages using single-cell RNA sequencing.tif by Chunxiang Cao (451327)

“…</p>Results<p>Cardiac function temporarily decreased on Day 7 and returned to normal level on Day 35, accompanied by macrophages decreased and increased respectively. …”

Potent Half-Sandwich Iridium(III) Anticancer Complexes Containing C^∧N‑Chelated and Pyridine Ligands by Zhe Liu (77240)

“…The monodentate py ligands blocked hydrolysis; however, antiproliferative studies showed that all the Ir compounds are highly active toward A2780, A549, and MCF-7 human cancer cells. In general the introduction of an electron-donating group (e.g., Me, NMe₂) at specific positions on the pyridine ring resulted in increased antiproliferative activity, whereas electron-withdrawing groups (e.g., COMe, COOMe, CONEt₂) decreased anticancer activity. …”

Table_3_Puerarin Alleviates Vascular Cognitive Impairment in Vascular Dementia Rats.XLSX by Tiantian Zhu (8254053)

“…Rats with BCCAO developed VD. Pur (50, 100, and 150 mg/kg) dose-dependently attenuated the pathological changes, increased synaptic structural plasticity in the dorsal CA1 hippocampal region and decreased oxidative stress, which eventually reduced cognitive impairment and vascular injury in BCCAO rats. …”

Image_1_Puerarin Alleviates Vascular Cognitive Impairment in Vascular Dementia Rats.TIF by Tiantian Zhu (8254053)

“…Rats with BCCAO developed VD. Pur (50, 100, and 150 mg/kg) dose-dependently attenuated the pathological changes, increased synaptic structural plasticity in the dorsal CA1 hippocampal region and decreased oxidative stress, which eventually reduced cognitive impairment and vascular injury in BCCAO rats. …”

Table_1_Puerarin Alleviates Vascular Cognitive Impairment in Vascular Dementia Rats.docx by Tiantian Zhu (8254053)

“…Rats with BCCAO developed VD. Pur (50, 100, and 150 mg/kg) dose-dependently attenuated the pathological changes, increased synaptic structural plasticity in the dorsal CA1 hippocampal region and decreased oxidative stress, which eventually reduced cognitive impairment and vascular injury in BCCAO rats. …”

Table_2_Puerarin Alleviates Vascular Cognitive Impairment in Vascular Dementia Rats.xlsx by Tiantian Zhu (8254053)

“…Rats with BCCAO developed VD. Pur (50, 100, and 150 mg/kg) dose-dependently attenuated the pathological changes, increased synaptic structural plasticity in the dorsal CA1 hippocampal region and decreased oxidative stress, which eventually reduced cognitive impairment and vascular injury in BCCAO rats. …”

DataSheet_1_Population-based study of the durability of humoral immunity after SARS-CoV-2 infection.pdf by David Peterhoff (5069261)

“…We investigated levels and temporal change of SARS-CoV-2 antibody quantity and quality. We analyzed sera (8 binding, 4 avidity assays for spike-(S-)protein and nucleocapsid-(N-)protein; neutralization) from 211 seropositive unvaccinated participants, from the population-based longitudinal TiKoCo study, at three time points within one year after infection with the ancestral SARS-CoV-2 virus. …”