Image1_Pharmacogenomic-guided clozapine administration based on HLA-DQB1, HLA-B and SLCO1B3-SLCO1B7 variants: an effectiveness and cost-effectiveness analysis.tiff by Kohei Ninomiya (9369628)

“…In this study, we evaluated the effectiveness and cost-effectiveness of adding the SLCO1B3-SCLO1B7 to HLA variants as a new pharmacogenomic (PGx) approach and explored the evolution of a cohort of schizophrenic patients taking long-term clozapine as a third-line antipsychotic medication. …”

<i>Syagrus coronata</i> fixed oil prevents rotenone-induced movement disorders and oxidative stress in <i>Drosophila melanogaster</i> by Ricardo Gomes dos Santos Nunes (18367900)

“…Young <i>Drosophila</i> specimens (3–4 d old) were exposed to a diet supplemented with rotenone (50 µM) for 7 d with and without the inclusion of <i>S. coronata</i> fixed oil (0.2 mg/g diet). …”

Image_1_Remarkable impacts of probiotics supplementation in enhancing of the antioxidant status: results of an umbrella meta-analysis.pdf by Vali Musazadeh (12304682)

“…</p>Results<p>Our results indicated that probiotics supplementation meaningfully decreased serum malondialdehyde (MDA) (ES_WMD = −0.56, 95% CI: −0.72, −0.39; p < 0.001, and ES_SMD = −0.50, 95% CI: −0.66, −0.34; p < 0.001). …”

Depletion of Rasa3 impairs EC adhesion turnover. by Patricia Molina-Ortiz (167505)

“…<p><b>A-B.</b> Activation of β1 integrin was analyzed in HUVECs transfected with control or Rasa3 siRNA <b>(A)</b> and in <i>R3</i>^f/f and <i>R3</i>^f/f iEC-Cre aortic ring sprouts <b>(B)</b> by confocal microscopy using an antibody specific for clustered β1 integrin. …”

Assessment of the Severity of Paravalvular Regurgitation and its Role on Survival After Transcatheter Aortic Valve Replacement by Anna Sannino (338344)

“…PVR was also graded as a composite score (PVR score), based on 6 commonly used metrics. …”

Data Sheet 1_SLNP-based CDK4- targeted nanotherapy against glioblastoma.docx by Uzma Ghani (20311140)

“…Introduction<p>Glioblastoma is a grade IV solid brain tumor and has a 15-month survival rate even after treatment. …”

Live Imaging of Label-Free Graphene Oxide Reveals Critical Factors Causing Oxidative-Stress-Mediated Cellular Responses by Sandra Vranic (4810767)

“…The interest in graphene and its translation into commercial products has been expanding at a high pace. Based on previously described pulmonary safety concerns for carbon nanomaterials, there is a great need to define parameters guiding interactions between graphene-based materials and the pulmonary system. …”

DataSheet1_Investigation of methane gas bubble dynamics and hydrate film growth during hydrate formation using 4-D time-lapse synchrotron X-ray computed tomography.docx by Shadman H. Khan (19431538)

“…<p>We present a time-lapse 4-D high-resolution synchrotron imaging study of the morphological evolution of methane gas bubbles and hydrate film growth on these bubbles. …”

Data_Sheet_2_Phylogeographic Assessment Reveals Geographic Sources of HIV-1 Dissemination Among Men Who Have Sex With Men in Kenya.docx by George M. Nduva (12216416)

“…Maximum-likelihood (ML) phylogenetics and Bayesian inference were used to determine HIV-1 clusters, evolutionary dynamics, and virus migration rates between geographic regions. HIV-1 sub-subtype A1 (72.0%) was most common followed by subtype D (11.0%), unique recombinant forms (8.9%), subtype C (5.9%), CRF 21A2D (0.8%), subtype G (0.8%), CRF 16A2D (0.3%), and subtype B (0.3%). …”

Data_Sheet_3_Male Embryos Produced in vitro Deviate From Their in vivo Counterparts in Placental Gene Expression on Day 32 of Pregnancy.xlsx by Jéssica N. Drum (12093062)

“…On day 32, the IVP group had a greater number of females than males (75 vs. 25%, P = 0.004). …”

Data_Sheet_1_Green nanotechnology for controlling bacterial load and heavy metal accumulation in Nile tilapia fish using biological selenium nanoparticles biosynthesized by Bacillu... by Ahmed M. Saad (14296973)

“…Secondly, heavy metals (Cd and Hg) at two levels (1 and 2 μg ml⁻¹) were reduced by 50–87% and 57–73% in response to Bio-SeNPs (3–5 μg ml⁻¹). …”

Table_3_QTL mapping and transcriptome analysis of sugar content during fruit ripening of Pyrus pyrifolia.xlsx by Shuang Jiang (1443706)

“…In sweet cultivars, sucrose and fructose accumulate substantially, and sorbitol content decreases significantly during fruit ripening. A transcriptome analysis identified 125 upregulated and 222 downregulated differentially expressed genes (DEGs) in sweet cultivars. …”

Histological and biochemical analysis of mice lacking Dicer in Schwann cells. by Juliane Bremer (161529)

“…At least four nerves were analyzed per genotype. Scale bars = 50 µm. S100 positivity indicates Schwann cell development progresses at least up to the stage of immature Schwann cells (<b>A</b>). …”

Abnormal cochlear connectivity in <i>Hoxb1</i>, <i>Hoxb2</i> and <i>Hoxa2</i> mutants. by Maria Di Bonito (280277)

“…AVCN, anterior ventral cochlear nucleus; PVCN, posterior ventral cochlear nucleus; PVCN IN, PVCN interneurons; MOC, medial olivocochlear neurons; aes, anterior extramural stream. Scale bars: 400 µm (A left panels, B), 50 µm (A right panels).</p>…”

Table_2_Identification of endothelial-related molecular subtypes for bladder cancer patients.docx by Deng-xiong Li (14819464)

“…The results of immune prediction analysis indicated that 50.6% (119/235) of patients in the cluster 1 responded to immunotherapy, while the response rate in the cluster 2 decreased to 16.7% (26/155).…”

Computing the Rotational Diffusion of Biomolecules via Molecular Dynamics Simulation and Quaternion Orientations by Po-chia Chen (1262706)

“…Over 2 μs trajectories, isotropic MARTINI+EN tumbling replicates experimental values to within 10–20%, with convergence analyses suggesting a minimum sampling of >50 × τ_theor to achieve sufficient precision. …”

New Polar Phases of 1,4-Diazabicyclo[2.2.2]octane Perchlorate, An NH⁺···N Hydrogen-Bonded Ferroelectric by Anna Olejniczak (1811986)

“…Phase II is stable up to 0.22 GPa, at 0.6 GPa phase III is formed, and above 1.50 GPa a new phase X (<i>Pc</i>2₁<i>a</i>) has been obtained. …”

Table_2_QTL mapping and transcriptome analysis of sugar content during fruit ripening of Pyrus pyrifolia.xlsx by Shuang Jiang (1443706)

“…In sweet cultivars, sucrose and fructose accumulate substantially, and sorbitol content decreases significantly during fruit ripening. A transcriptome analysis identified 125 upregulated and 222 downregulated differentially expressed genes (DEGs) in sweet cultivars. …”

Table_1_QTL mapping and transcriptome analysis of sugar content during fruit ripening of Pyrus pyrifolia.xlsx by Shuang Jiang (1443706)

“…In sweet cultivars, sucrose and fructose accumulate substantially, and sorbitol content decreases significantly during fruit ripening. A transcriptome analysis identified 125 upregulated and 222 downregulated differentially expressed genes (DEGs) in sweet cultivars. …”

The Ability of Flux Balance Analysis to Predict Evolution of Central Metabolism Scales with the Initial Distance to the Optimum by William R. Harcombe (93324)

“…For ten populations that were evolved for 50,000 generations in glucose minimal medium, we observed modest changes in relative fluxes that led to small, but significant decreases in optimality and increased the distance to the predicted optimal flux distribution. …”