Loss of BAP1 expression is associated with genetic mutation and can predict outcomes in gallbladder cancer by Takashi Hirosawa (5931845)

“…Sanger sequencing revealed a loss-of-function mutation of <i>BAP1</i> in 11 out of these 22 GBC cases (50%) with low BAP1 expression, whereas 2 out of 25 GBC cases (8%) were detected in cases with high BAP1 expression. …”

Image_4_Hybrid Nanoparticles as an Efficient Porphyrin Delivery System for Cancer Cells to Enhance Photodynamic Therapy.TIF by Letícia B. Silva (11447653)

“…<p>Photodynamic therapy (PDT) is a potential non-invasive approach for application in oncological diseases, based on the activation of a photosensitizer (PS) by light at a specific wavelength in the presence of molecular oxygen to produce reactive oxygen species (ROS) that trigger the death tumor cells. …”

Kisspeptin expression by human term placenta. by Zahra Rasoulzadeh (2622283)

“…KPs: Kisspeptin, CK7: Cytokeratin 7, TP: Term placenta, FTP: First trimester placenta, NC: Negative control. Scale bar: A; 100 μm, B; 50μm.</p>…”

Image_5_Hybrid Nanoparticles as an Efficient Porphyrin Delivery System for Cancer Cells to Enhance Photodynamic Therapy.TIF by Letícia B. Silva (11447653)

“…<p>Photodynamic therapy (PDT) is a potential non-invasive approach for application in oncological diseases, based on the activation of a photosensitizer (PS) by light at a specific wavelength in the presence of molecular oxygen to produce reactive oxygen species (ROS) that trigger the death tumor cells. …”

Data_Sheet_1_Protein and Signaling Pathway Responses to rhIL-6 Intervention Before Lobaplatin Treatment in Osteosarcoma Cells.PDF by Huan Wang (109286)

“…The immunofluorescence staining results were in accord with the immunohistochemistry staining results. siRNA knockdown of FUBP1 showed a strikingly decreased IC50 value for lobaplatin in FUBP1-silenced cells, which verified the role of FUBP1 in the drug susceptibility of osteosarcoma and the potential therapeutic value for increasing the sensitivity to lobaplatin. …”

Image_2_Hybrid Nanoparticles as an Efficient Porphyrin Delivery System for Cancer Cells to Enhance Photodynamic Therapy.TIF by Letícia B. Silva (11447653)

“…<p>Photodynamic therapy (PDT) is a potential non-invasive approach for application in oncological diseases, based on the activation of a photosensitizer (PS) by light at a specific wavelength in the presence of molecular oxygen to produce reactive oxygen species (ROS) that trigger the death tumor cells. …”

Table_1_Distinct Brain Regions in Physiological and Pathological Brain Aging.docx by Jin San Lee (6849692)

“…In this study, we investigated the long-term trajectory of physiological and pathological brain aging in a large number of participants ranging from the 50s to over 80 years of age.…”

Single cell gene expression analysis demonstrates transcriptional variation in murine LT-HSCs. by Jason P. Glotzbach (216727)

“…Error bars represent standard deviations derived through bootstrapping over 100,000 iterations as previously described <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0021211#pone.0021211-Efron1" target="_blank">[50]</a>.…”

Image_1_Hybrid Nanoparticles as an Efficient Porphyrin Delivery System for Cancer Cells to Enhance Photodynamic Therapy.TIF by Letícia B. Silva (11447653)

“…<p>Photodynamic therapy (PDT) is a potential non-invasive approach for application in oncological diseases, based on the activation of a photosensitizer (PS) by light at a specific wavelength in the presence of molecular oxygen to produce reactive oxygen species (ROS) that trigger the death tumor cells. …”

Image_3_Hybrid Nanoparticles as an Efficient Porphyrin Delivery System for Cancer Cells to Enhance Photodynamic Therapy.TIF by Letícia B. Silva (11447653)

“…<p>Photodynamic therapy (PDT) is a potential non-invasive approach for application in oncological diseases, based on the activation of a photosensitizer (PS) by light at a specific wavelength in the presence of molecular oxygen to produce reactive oxygen species (ROS) that trigger the death tumor cells. …”

DataSheet1_Computational design of custom therapeutic cells to correct failing human cardiomyocytes.pdf by Andrew Tieu (14441499)

“…Using a genetic algorithm-based optimization approach, candidate cells were accepted if a root mean square error (RMSE) of less than 50% relative to healthy hCM was achieved for both action potential and calcium transient waveforms for the cell-treated HF cardiomyocyte, normalized to the untreated HF cardiomyocyte.…”

Data_Sheet_1_Interaction of energy and sulfur microbial diet and smoking status with polygenic variants associated with lipoprotein metabolism.PDF by Haeng Jeon Hur (6808157)

“…The risk alleles of CETP_rs708272 and ALDH1A2_rs588136 were linked to increased expression in the heart and decreased in the brain, respectively. …”

DataSheet_1_Genetic Screening for TLR7 Variants in Young and Previously Healthy Men With Severe COVID-19.pdf by Xavier Solanich (7447049)

“…Functional testing of this variant revealed decreased type I and II interferon responses in peripheral mononuclear blood cells upon stimulation with the TLR7 agonist imiquimod, confirming a loss-of-function effect.…”

DataSheet1_Computational design of custom therapeutic cells to correct failing human cardiomyocytes.pdf by Andrew Tieu (14441499)

“…Using a genetic algorithm-based optimization approach, candidate cells were accepted if a root mean square error (RMSE) of less than 50% relative to healthy hCM was achieved for both action potential and calcium transient waveforms for the cell-treated HF cardiomyocyte, normalized to the untreated HF cardiomyocyte.…”

Image 1_Caffeine on the mind: EEG and cardiovascular signatures of cortical arousal revealed by wearable sensors and machine learning—a pilot study on a male group.jpeg by Shabbir Chowdhury (22246345)

“…Although systolic and diastolic BP showed a non-significant upward trend, HR decreased significantly after caffeine intake (77 ± 5.3 bpm to 72 ± 2.5 bpm, p = 0.027). …”

Effects of <i>T</i>. <i>gondii</i> infection on fear memory consolidation in mice. by Fumiaki Ihara (4592044)

“…The average freezing response percentage across the 5 min intervals in the extinction test was normalized to the first 5 min. …”

Overexpression of Smad7 in airway epithelium alleviates allergic inflammation and airway remodeling. by Xiaolin Luo (228775)

“…The mouse serum was analyzed for OVA-specific IgE by ELISA. Values are mean ± SD from five mice per group.</p>…”

Time course of the wound contraction rates. by Hitomi Sano (296853)

“…<p>Wound size significantly decreased in the normoxia group in comparison with the hypoxia group on day 5 and 7. …”

Table_1_Post-silking Phosphorus Recycling and Carbon Partitioning in Maize Under Low to High Phosphorus Inputs and Their Effects on Grain Yield.DOCX by Chao Wang (146527)

“…Despite the higher P uptake with P fertilization above this threshold, the lack of additional plant growth and yield resulted in decreased P-use efficiency. Regardless of P application rates, P remobilization to the ear during the first half of the grain filling phase preferentially came from the stem (50–76%) rather than from leaves (30–44%), and with a greater proportion in the inorganic P (Pi) form over organic P fractions. …”

Profiling overall protein <i>O</i>-glycosylation pathway genes in <i>F. graminearum.</i> by Heeji Moon (17474719)

“…Sexual developments were categorized as discrete phenotypic traits and scored on a 4-point scale (a: no difference compared with wild-type, b: decreased number of perithecia and ascospore or delayed perithecia maturation or decreased number of discharged ascospores, c: no perithecia and ascospore formation or no ascospore discharge, e: essential genes). …”