The Number of Patients and Events Required to Limit the Risk of Overestimation of Intervention Effects in Meta-Analysis—A Simulation Study by Kristian Thorlund (149383)

“…<div><h3>Background</h3><p>Meta-analyses including a limited number of patients and events are prone to yield overestimated intervention effect estimates. …”

Nutritional Support for Patients Sustaining Traumatic Brain Injury: A Systematic Review and Meta-Analysis of Prospective Studies by Xiang Wang (127867)

“…Small-bowel feeding was found to be with a decreasing rate of pneumonia compared with nasogastric feeding (RR = 0.41; 95% CI, 0.22–0.76).…”

An Early-Onset Subgroup of Type 2 Diabetes: A Multi-Generational, Prospective Analysis in the Framingham Heart Study by Justin B. Echouffo-Tcheugui (9388233)

“…In second-generation participants, having a parent with early-onset diabetes increased diabetes risk by 3.24-fold (1.73-6.07) whereas having one or both parents with late-onset diabetes increased diabetes risk by 2.19-fold (1.50-3.19).…”

Image_1_Effects of Perioperative Dexmedetomidine on Immunomodulation in Uterine Cancer Surgery: A Randomized, Controlled Trial.tif by Jin Sun Cho (11710808)

“…Objective<p>Dexmedetomidine has sympatholytic, anti-inflammatory, and analgesic effects and may exert anti-tumor effect by acting on α2A adrenoreceptor. We investigated whether perioperative dexmedetomidine preserves immune function in patients undergoing uterine cancer surgery.…”

Data_Sheet_1_Therapy-Induced Electrophysiological Changes in Primary Progressive Aphasia: A Preliminary Study.docx by Jara Stalpaert (9234844)

“…In the two patients that did not receive SLT, an increased delay in 50% and a decreased mean amplitude in 25% of the measured ERP components were found. …”

DataSheet1_A novel hybrid bioprocess strategy addressing key challenges of advanced biomanufacturing.PDF by Lucas Nik Reger (14632742)

“…The novel process showed increased productivity (+217%) as well as longer cultivation duration, in comparison to a standard FB with a significantly lower media consumption per produced product (−50%) and a decreased need for process monitoring, in comparison to a perfusion cultivation. …”

Datasheet1_Fever management in children and insights into fever of unknown origin: a survey among Italian pediatricians.pdf by Elena Chiappini (304802)

Data Sheet 1_Cytomegalovirus infection in infants with biliary atresia in China: a multi-center investigation study.docx by Yilin Zhao (487866)

“…</p>Conclusion<p>Among the 1,276 infants with BA in this cohort, 31.3% (399 cases) had concomitant CMV infection, representing a decrease compared to previous data. CMV-IgM played a crucial role in the detection of the infection. …”

Image_1_TnP Peptide Suppresses Experimental Autoimmune Encephalomyelitis (EAE) in a Preclinical Mouse Model.pdf by Carla Lima (428557)

“…We have shown that TnP possesses a disease suppressive function in EAE, ameliorating disease severity by 40% and suppressing the accumulation of T helper (Th)1- and Th17-producing lymphocytes (by 55% and 60%, respectively) in CNS along with activated microglia/macrophages populations (by 33% and 50%, respectively), and also conferred a protective effect anticipating the remyelination process to day 66 compared to day 83 of untreated cuprizone-mice. …”

Video_3_Pericardial Injection of Kainic Acid Induces a Chronic Epileptic State in Larval Zebrafish.MP4 by Lise Heylen (11561266)

Video_2_Pericardial Injection of Kainic Acid Induces a Chronic Epileptic State in Larval Zebrafish.MP4 by Lise Heylen (11561266)

Analyses of the mitochondrial complex I activity and ATP and ROS productions in Pns10-GFP expressing Sf9 cells and RRSV viruliferous <i>N. lugens.</i> by Lianshun Zheng (22086585)

Glycosylation sites in spike and effects of glycan loss on pseudoviruses infectivity. by Sabrina Lusvarghi (2329267)

VER-155008 caused a significant reduction in viral transcripts in HEK-293T rKSHV.219 cells. by Belinda Baquero-Pérez (706834)

“…(C) At 4 h AcD treatment <i>SRAG</i> mRNA levels were reduced by 50% showing a relatively short stability. (D) <i>H2A</i>.…”

Hydroxysafflor Yellow A Ameliorates Renal Fibrosis by Suppressing TGF-β1-Induced Epithelial-to-Mesenchymal Transition by Naping Hu (2614399)

“…The aim of this study was to investigate whether Hydroxysafflor yellow A (HSYA) can preserve renal function by inhibiting the progression of renal fibrosis and the potential mechanisms.…”

Supplementary Material for: Association between Hypouricemia and Reduced Kidney Function: A Cross-Sectional Population-Based Study in Japan by Wakasugi M. (4152238)

“…Hypouricemia was associated with reduced kidney function in men (odds ratio, 1.83; 95% confidence interval, 1.23-2.74), but not in women (0.61; 0.43-0.86), relative to the reference category (i.e., serum uric acid levels of 4.1-5.0 mg/dl) after adjusting for age, drinking, smoking, diabetes, hypertension, hypercholesterolemia, obesity, and history of renal failure. …”

ARHGAP15 protects GC cells from oxidative stress-induced cell death. by Fei-fei Zhang (10167371)

ARHGAP15 promotes ECM-detached tumor cell survival and colony formation under oxidative stress. by Fei-fei Zhang (10167371)

Table_1_Evolving a New Efficient Mode of Fructose Utilization for Improved Bioproduction in Corynebacterium glutamicum.DOCX by Irene Krahn (10888566)

“…This is known to result in a significantly reduced oxidative pentose phosphate pathway (oxPPP) flux on fructose (∼10%) compared to glucose (∼60%). …”

Table_1_Causal association of gut microbiota on spondyloarthritis and its subtypes: a Mendelian randomization analysis.xlsx by Jun Tang (32983)

“…The family Rikenellaceae id.967 was associated with a reduced risk of both AS (OR = 0.66 (95% CI: 0.47–0.93); p = 1.81E−02) and psoriatic arthritis (OR = 0.70 (95% CI: 0.50–0.97); p = 3.00E−02). …”