Table_3_Relevance of PUFA-derived metabolites in seminal plasma to male infertility.docx by Xiangfeng Chen (1548517)

“…In men with normozoospermia, higher levels of 7(R)-MaR1 (HR: 0.4 (95% CI [0.24, 0.64]) and 11,12-DHET (0.36 (95% CI [0.21, 0.58]) were significantly associated with a decreased risk of infertility, while higher levels of 17(S)-HDHA (HR: 2.32 (95% CI [1.44, 3.79]), LXA5 (HR: 8.38 (95% CI [4.81, 15.24]), 15d-PGJ2 (HR: 1.71 (95% CI [1.06, 2.76]), and PGJ2 (HR: 2.28 (95% CI [1.42, 3.7]) correlated with an increased risk of infertility. …”

Co-localization of Mmi1 with proteasomes. by Mark Rinnerthaler (477426)

“…We conclude that heat shock results in increase of the proteasomal activity and a presence of Mmi1 displays an inhibitory function in regulation of the proteasomal activity which is most pronounced after heat-shock.…”

Integrative Approach Detected Association between Genetic Variants of microRNA Binding Sites of TLRs Pathway Genes and OSCC Susceptibility in Chinese Han Population by Yun Wang (32846)

“…<div><p>Oral squamous cell carcinoma (OSCC) is a leading malignancy worldwide; the overall 5-year survival rate is approximately 50%. …”

GIT1 and LAR depletion inhibit cell spreading and prevent enhanced spreading by liprin-α1 overexpression. by Claudia Asperti (217787)

“…<p>(A) Specific and control (Luc = luciferase) siRNA duplexes were used to downregulate the expression of endogenous GIT1, GIT2, liprin-α1 and LAR in COS7 cells. …”

Reappraisal of the Trophic Ecology of One of the World’s Most Threatened Spheniscids, the African Penguin by Maëlle Connan (680842)

“…The world population of the endangered African penguin <i>Spheniscus demersus</i> has decreased from more than 1.5 million individuals in the early 1900s to c.a. 23 000 pairs in 2013. …”

Data Sheet 1_Lipoxin A4 levels correlate with severity in a Spanish COVID-19 cohort: potential use of endogenous pro-resolving mediators as biomarkers.docx by Sergio Sánchez-García (16862127)

“…We found reduced levels in deceased patients when compared to mild or severe patients, concomitant with a decrease in the LXA₄ biosynthetic pathway and an increase in its degradation pathway. …”

Image 6_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpeg by Eisa Mahyari (9681962)

“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27^pos), AS+AAU (HLA-B27^pos), AAU (HLA-B27^pos), HCs (HLA-B27^pos), and HCs (HLA-B27^neg); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”

Image 9_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpeg by Eisa Mahyari (9681962)

“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27^pos), AS+AAU (HLA-B27^pos), AAU (HLA-B27^pos), HCs (HLA-B27^pos), and HCs (HLA-B27^neg); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”

Table_1_Photosynthetic Carbon Fixation and Sucrose Metabolism Supplemented by Weighted Gene Co-expression Network Analysis in Response to Water Stress in Rice With Overlapping Grow... by Xinpeng Wang (4611307)

“…The results showed that short-term drought stress promoted photosynthetic carbon fixation. However, ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) activity significantly decreased, resulting in a significant decrease in photosynthetic rate. …”

Data_Sheet_1_Diabetes Mellitus Is an Independent Risk Factor for a Stiff Left Atrial Physiology After Catheter Ablation for Atrial Fibrillation.PDF by Moon-Hyun Kim (12044069)

“…After 1:3 propensity score (PS) matching for age, sex, and AF type, we compared 211 patients with DM with 633 patients without DM. …”

Presentation_1_Small-Medium Extracellular Vesicles and Their miRNA Cargo in Retinal Health and Degeneration: Mediators of Homeostasis, and Vehicles for Targeted Gene Therapy.pdf by Yvette Wooff (4955854)

“…Isolated s-mEV from normal retinas were characterized using dynamic light scattering, transmission electron microscopy and western blotting, and quantified across 5 days of photo-oxidative damage-induced degeneration using nanotracking analysis. …”

Table 1_Coordinated regulation of IGF1R by HIF1α and HIF2α enhances chemoresistance in glioblastoma.docx by Bin Liao (714989)

“…In addition, we demonstrated that HIF1α and HIF2α promoted IGF1R expression by binding to a specific hypoxia response element (HRE) sequence (5′-GAACGTGCCT-3′) within the IGF1R promoter using dual-luciferase reporter system.…”

Table_1_Association between baseline pulse pressure and hospital mortality in non-traumatic subarachnoid hemorrhage patients: a retrospective cohort study.DOC by Jiuling Liu (16327938)

“…In the threshold analysis, for every 5 mmHg increase in PP level, there was an 18.2% decrease in hospital mortality (adjusted HR, 0.818; 95% CI, 0.738–0.907; p = 0.0001) in those with PP level less than 60 mmHg, and a 7.7% increase in hospital mortality (adjusted HR, 1.077; 95% CI, 1.018–1.139; p = 0.0096) in those with PP level was 60 mmHg or higher.…”

Data Sheet 1_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.docx by Eisa Mahyari (9681962)

“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27^pos), AS+AAU (HLA-B27^pos), AAU (HLA-B27^pos), HCs (HLA-B27^pos), and HCs (HLA-B27^neg); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”

The complete workflow employed in this study. by Md. Mostafa Kamal (13514317)

“…Out of these, 186 missense variants (5.93%), 1491 intron variants (47.57%), and 91 synonymous variants (2.90%), while the remaining SNPs were unspecified. …”

Data_Sheet_1_Age-Related Changes in the Gut Microbiota Modify Brain Lipid Composition.pdf by Mayssa Albouery (8294364)

“…Transplantation of microbiota from old mice also modified the lipid class and fatty acid content in the liver. Finally, we found that the expression of several genes involved in MUFA and PUFA synthesis (Scd1, Fads1, Fads2, Elovl2, and Elovl5) was dysregulated in mice inoculated with an aged microbiota. …”

Table 2_Global burden and trends of norovirus-associated diseases from 1990 to 2021 an observational trend study.xlsx by MengLan Zhu (20517257)

“…For trend analysis, we employed annual percentage change (EAPC) through linear regression and applied Joinpoint analysis to identify significant changes over time. …”

DataSheet_1_Treatment-Induced BAFF Expression and B Cell Biology in Multiple Sclerosis.docx by Ide Smets (10875969)

“…Protein BAFF correlated with an increase in transitional B cells (P = 5.70 x 10^-6), decrease in switched B cells (P = 3.29 x 10^-4), and reduction in B cell-surface BAFF-R expression (P = 2.70 x 10^-10), both on TACI-positive and -negative cells. …”

Trends in Glucose Lowering Drug Utilization, Glycemic Control, and Severe Hypoglycemia in Adults with Diabetes in Hong Kong 2002-2016 by Aimin Yang (393426)

“…The main improvement in HbA1c occurred between 2007 and 2014, decreasing from mean (SD) 7.6 (1.6)% (59.5 [19.0] mmol/mol) to 7.2 (1.7)% (54.8 [18.9] mmol/mol) (p<0.001). …”

Table 3_Global burden and trends of norovirus-associated diseases from 1990 to 2021 an observational trend study.xlsx by MengLan Zhu (20517257)

“…For trend analysis, we employed annual percentage change (EAPC) through linear regression and applied Joinpoint analysis to identify significant changes over time. …”