Protective Effect of Combined Metoprolol and Atractylenolide I in Rats with Acute Myocardial Infarction via Modulation of the SIRT3/β-CATENIN/PPAR-γ Signaling Pathway by Weijian Zhou (1592806)

“…<div><p>ABSTRACT Herein, we examined the protective effect of metoprolol combined with atractylenolide I (Atr I) in acute myocardial infarction (AMI) by regulating the SIRT3 (silent information regulator 3)/β-catenin/peroxisome proliferator-activated receptor gamma (PPAR-γ) signaling pathway. …”

Spatio-Temporal Dynamics of Foraging Networks in the Grass-Cutting Ant <i>Atta bisphaerica</i> Forel, 1908 (Formicidae, Attini) by Juliane F. S. Lopes (845017)

“…The foraging networks consisted of underground tunnels which opened on average at 21.5m from the nests and of above-ground physical trails that reached on average 4.70m in length. …”

Supplementary Material for: Interleukin-17A Promotes Arginase-1 Production and 2,4-Dinitrochlorobenzene-Induced Acute Hyperinflammation in Human Papillomavirus E7 Oncoprotein-Expre... by Tran L.S. (3632413)

“…Further, blockade of either IL-17A or arginase activity alleviates DNCB-induced hyperinflammation through reduced recruitment of neutrophils, as a consequence of decreased CXCL1 and CXCL5 chemokine production. Thus, our findings suggest that increased IL-17A expression by macrophages in E7-expressing skin exposed to DNCB promotes arginase-1 induction and contributes directly to the observed hyperinflammation.…”

Image_6_The Impact of Mercury Selection and Conjugative Genetic Elements on Community Structure and Resistance Gene Transfer.JPEG by James P. J. Hall (9207143)

“…Nevertheless, the introduced merA gene spread to a phylogenetically diverse set of recipients over the 5 weeks of the experiment, as assessed by epicPCR. …”

<em>Foxa1</em> and <em>Foxa2</em> Are Required for Formation of the Intervertebral Discs by Jennifer A. Maier (278698)

“…Using a conditional <em>Foxa2</em> allele in conjunction with a tamoxifen-inducible <em>Cre</em> allele (<em>ShhcreER^T2</em>), we removed <em>Foxa2</em> from the notochord of E7.5 mice null for <em>Foxa1</em>. …”

Image_7_Subchronic Toxicity of Microcystin-LR on Young Frogs (Xenopus laevis) and Their Gut Microbiota.TIF by Jinjin Li (849002)

“…MC-LR significantly decreased the activities of malondialdehyde and alkaline phosphatase and the expression of TGF-β in the liver. …”

Non-invasive hypoglycemia detection in people with diabetes using smartwatch data by Vera Lehmann (9383845)

“…Using this data, we developed a machine learning (ML) approach to detect hypoglycemia (<3.9 mmol/L) non-invasively on unseen individuals and solely based on wearable data.…”

Table_1_Serum autoantibody profiling of oral squamous cell carcinoma patients reveals NUBP2 as a potential diagnostic marker.xlsx by Riaz Abdulla (17024742)

“…</p>Results and discussion<p>We identified a total of 53 autoantibodies with significant differential levels between OSCC and control groups, including 25 that were increased in OSCC and 28 that were decreased. …”

Image_3_The Impact of Mercury Selection and Conjugative Genetic Elements on Community Structure and Resistance Gene Transfer.JPEG by James P. J. Hall (9207143)

“…Nevertheless, the introduced merA gene spread to a phylogenetically diverse set of recipients over the 5 weeks of the experiment, as assessed by epicPCR. …”

Table_1_Application of the Artificial Intelligence Algorithm Model for Screening of Inborn Errors of Metabolism.XLSX by Muping Zhou (12564601)

“…Mutations in phenylalanine hydroxylase (PAH) and SLC22A5 were the leading causes of IEMs. To evaluate the application effect of artificial intelligence (AI) in newborn screening, we used AI to retrospectively analyze the screening results and found that the false-positive rate could be decreased by more than 24.9% after using AI. …”

Data_Sheet_1_Effects of cottonseed meal protein hydrolysate on intestinal microbiota of yellow-feather broilers.docx by Xiaoyang Zhang (196062)

“…We randomly divided 240 chicks into four groups with six replicates: basal diet with 0% (CON), 1% (LCPH), 3% (MCPH), or 5% (HCPH) CPH. …”

Role of the YAP Oncoprotein in Priming Ras-Driven Rhabdomyosarcoma by Katherine K. Slemmons (817850)

“…Survival for high-risk groups is less than 30% at 5 years. RMS also occurs during adulthood, with a lower incidence but higher mortality. …”

Table2_Preclinical Evidence of Paeoniflorin Effectiveness for the Management of Cerebral Ischemia/Reperfusion Injury: A Systematic Review and Meta-Analysis.DOCX by Anzhu Wang (5501090)

“…Review Manager 5.3 and STATA 12.0 software were used for meta-analysis.…”

Video2_Novel Biallelic Variant in the BRAT1 Gene Caused Nonprogressive Cerebellar Ataxia Syndrome.MP4 by Yiming Qi (780014)

“…Recently, attenuated disease variants have been described, suggesting that a wider clinical spectrum of BRAT1-associated neurodegeneration exists than was previously thought. Here, we reported a 10-year-old girl with severe intellectual disability, rigidity, ataxia or dyspraxia, and cerebellar atrophy on brain MRI; two BRAT1 variants in the trans configuration [c.1014A > C (p.Pro338 = ); c.706delC (p.Leu236Cysfs*5)] were detected using whole-exome sequencing. …”

Supplementary Material for: When Uveitis and Hypotony Meets Bilateral Iris Retraction Syndrome: A Rare but Serious Complication of Nivolumab Treatment by Kandarakis S.A. (18862084)

“…Methods and Results: We present a case of bilateral IRS with hypotony, 3mmHg OD and 5mmHg OS, after therapy with Nivolumab. …”

Image_2_First-Episode Psychotic Patients Showed Longitudinal Brain Changes Using fMRI With an Emotional Auditory Paradigm.tif by Carlos González-Vivas (9759098)

“…Results were compared with a pair of healthy control group (n = 13). Patients showed a decreased activation at follow-up fMRI in amygdala (F = 4.69; p = 0.04) and hippocampus (F = 5.03; p = 0.03) compared with controls. …”

Table_1_Muscle Atrophy Due to Nerve Damage Is Accompanied by Elevated Myofibrillar Protein Synthesis Rates.DOCX by Henning T. Langer (5705057)

“…This is the case despite substantial loss of mass of the TA (350 ± 96 mg [damaged] to 946 ± 361 mg [control]). We also show that expression of regulatory proteins involved with MPS (p70s6k1: 2.4 ± 0.3 AU [damaged] to 1.8 ± 0.2 AU [control]) and muscle protein breakdown (MPB) (MAFbx: 5.3 ± 1.2 AU [damaged] to 1.4 ± 0.4 AU [control]) are increased in nerve damaged muscle. …”

Capillary HILIC-MS: A New Tool for Sensitive Top-Down Proteomics by Andrea F.G. Gargano (5236496)

“…Here, we introduce a capillary-based HILIC-MS method that overcomes these problems. …”

Image1_Guhong Injection Alleviates Cerebral Ischemia–Reperfusion Injury via the PKC/HIF-1α Pathway in Rats.TIF by Li Yu (81651)

“…After establishing an MCAO rat model, we performed neurological deficit testing, 2,3,5-triphenyltetrazolium chloride staining, hematoxylin and eosin (HE) staining, enzyme-linked immunosorbent assay, Western blotting, and q-PCR to detect the brain damage in rats. …”

Semen analysis raw data. by Jiatong Xiao (15344134)

“…Our aim was to estimate changes in sexual function and semen quality in men recovering from infection since the COVID-19 Omicron pandemic started in China in late 2022. We collected 1540 questionnaires and assessed male function before infection and acute phase after infection by using International Index of Erectile Function-5, Premature Ejaculation Diagnostic Tool, and Arizona Sexual Experience Scale. …”