Identification of SNAIL1 Peptide-Based Irreversible Lysine-Specific Demethylase 1‑Selective Inactivators by Yukihiro Itoh (433923)

Reproducing on Time When Temperature Varies: Shifts in the Timing of Courtship by Fiddler Crabs by Kecia A. Kerr (564973)

“…We tested this idea by studying the timing of courtship in <i>U. terpsichores</i> and <i>U. deichmanni</i> as temperature varied annually during two years, at 5 locations that differed in the temperature of the sediment where females incubate their eggs. …”

Table_2_Application of the Artificial Intelligence Algorithm Model for Screening of Inborn Errors of Metabolism.XLSX by Muping Zhou (12564601)

“…Mutations in phenylalanine hydroxylase (PAH) and SLC22A5 were the leading causes of IEMs. To evaluate the application effect of artificial intelligence (AI) in newborn screening, we used AI to retrospectively analyze the screening results and found that the false-positive rate could be decreased by more than 24.9% after using AI. …”

Periodic Ice Banding in Freezing Colloidal Dispersions by Anthony M. Anderson (2017657)

“…We discuss the implications of our experimental findings for theories of ice lensing.…”

Effectiveness of a serious game for medical education on insulin therapy: a pilot study by Leandro A. Diehl (6144782)

“…<div><p>Objective We report the preliminary assessment of InsuOnline©, a serious game designed for medical education on insulin therapy.Materials and methods We conducted a pilot study with 41 undergraduate medical students and Internal Medicine residents to assess the educational effectiveness of InsuOnline©, as compared to a traditional educational activity (lecture, cases discussion). …”

Table_2_First-Episode Psychotic Patients Showed Longitudinal Brain Changes Using fMRI With an Emotional Auditory Paradigm.docx by Carlos González-Vivas (9759098)

“…Results were compared with a pair of healthy control group (n = 13). Patients showed a decreased activation at follow-up fMRI in amygdala (F = 4.69; p = 0.04) and hippocampus (F = 5.03; p = 0.03) compared with controls. …”

Video3_Novel Biallelic Variant in the BRAT1 Gene Caused Nonprogressive Cerebellar Ataxia Syndrome.MP4 by Yiming Qi (780014)

“…Recently, attenuated disease variants have been described, suggesting that a wider clinical spectrum of BRAT1-associated neurodegeneration exists than was previously thought. Here, we reported a 10-year-old girl with severe intellectual disability, rigidity, ataxia or dyspraxia, and cerebellar atrophy on brain MRI; two BRAT1 variants in the trans configuration [c.1014A > C (p.Pro338 = ); c.706delC (p.Leu236Cysfs*5)] were detected using whole-exome sequencing. …”

<i>SmoA1</i> +; <i>Pten</i> +/− medulloblastomas down-regulate expression of targets of <i>sonic hedgehog</i> (<i>Shh</i>) signaling. by Robert C. Castellino (248365)

“…Relative expression of <i>Gli1</i>, <i>Gli2</i>, <i>N-myc</i>, and <i>cyclin-D1</i> was decreased 5.6, 7.6, 4.3, and 2.8-fold (<b>*</b>, p<0.05 for all transcripts), respectively in <i>SmoA1</i> +; <i>Pten</i> +/− (white bars) medulloblastomas. …”

Data_Sheet_1_Local-scale impacts of water hyacinth on water quality in a hypereutrophic lake.docx by Jessica R. Corman (14555561)

“…While our study did not show overwhelming improvements in water quality with increasing water hyacinth density, we did find that small-scale removal of water hyacinth led to decreases in coliforms (F_{1, 11} = 11.14, p < 0.01), E. coli (F_{1, 11} = 22.95, p < 0.001), and total microcystins (F_{1, 9} = 3.47, p = 0.095). …”

Table 1_Carnosine as a protective metabolic mediator in inflammatory lung injury by inhibiting macrophage infiltration and M1-like polarization.docx by Lianjie Ruan (22660265)

“…</p>Methods<p>Using targeted metabolomic profiling of lung tissues collected on day 5 from two distinct murine models of lung inflammation—lipopolysaccharide (LPS)-induced and papain-induced—we identified carnosine as a commonly downregulated metabolite in both models. …”

Supplementary file 1_The effects of vessel speed and size on the lethality of strikes of large whales in U.S. waters.xlsx by Lance P. Garrison (2469937)

“…We found a significant effect of vessel size class on the probability of lethality. …”

α-Lipoic acid prevents against cisplatin cytotoxicity via activation of the NRF2/HO-1 antioxidant pathway by Joohyung Lee (1488208)

“…E<i>x vivo</i>, the organs of Corti of the group pretreated with LA exhibited better preservation than the group that received cisplatin alone. We also confirmed the nuclear translocation of NRF2 after LA administration, and that NRF2 inhibition decreased the antioxidant activity of LA. …”

Image_1_The Impact of Mercury Selection and Conjugative Genetic Elements on Community Structure and Resistance Gene Transfer.JPEG by James P. J. Hall (9207143)

“…Nevertheless, the introduced merA gene spread to a phylogenetically diverse set of recipients over the 5 weeks of the experiment, as assessed by epicPCR. …”

Data_Sheet_1_Identification of a Devernalization Inducer by Chemical Screening Approaches in Arabidopsis thaliana.pdf by Makoto Shirakawa (746386)

“…This is referred to as devernalization. In this study, we identified a novel chemical compound, 4-Isoxazolecarboxylic acid, 3,5-dimethyl-2-(4-fluorophenyl)-4-isoxazole carboxylic acid 1-methyl-2-oxoethyl ester named as DEVERNALIZER01 (DVR01), which induces devernalization in Arabidopsis seedlings, by an FLC-luciferase reporter-based high-throughput screening assay. …”

The original data of survey. by Jiatong Xiao (15344134)

“…Our aim was to estimate changes in sexual function and semen quality in men recovering from infection since the COVID-19 Omicron pandemic started in China in late 2022. We collected 1540 questionnaires and assessed male function before infection and acute phase after infection by using International Index of Erectile Function-5, Premature Ejaculation Diagnostic Tool, and Arizona Sexual Experience Scale. …”

Physiological and Molecular Alterations Promoted by <i>Schizotetranychus oryzae</i> Mite Infestation in Rice Leaves by Giseli Buffon (1392436)

Genetic Variants in <em>PNPLA3</em> and Risk of Non-Alcoholic Fatty Liver Disease in a Han Chinese Population by Xian-E Peng (116291)

“…Furthermore, haplotype association analysis showed that, compared with the most common haplotype, the CAAGAA<b>TG</b>CGTG and CGAAGG<b>TG</b>TCCG haplotypes conferred a statistically significant increased risk for NAFLD, while the CGGGAA<b>CC</b>CGCG haplotype decreased the risk of NAFLD. Moreover, rs738409 C>G appeared to have a multiplicative joint effect with tea drinking (P<0.005) and an additive joint effect with obesity (Interaction contrast ratio (ICR) = 2.31, 95% CI: 0.7–8.86), hypertriglyceridemia (ICR = 3.07, 95% CI: 0.98–5.09) or hypertension (ICR = 1.74, 95% CI: 0.52–3.12). …”

High Durability and Waterproofing rGO/SWCNT-Fabric-Based Multifunctional Sensors for Human-Motion Detection by Seong Jun Kim (1568476)

“…Finally, we demonstrated a fabric-sensor-based motion glove and confirmed its practical applicability.…”

Data_Sheet_1_Behavioral and Molecular Consequences of Chronic Sleep Restriction During Development in Fragile X Mice.PDF by R. Michelle Saré (12961376)

“…To test our hypothesis, we sleep-restricted Fmr1 knockout (KO) mice for 3 h per day from P5 to P52 and subjected mice to behavioral tests beginning on P42. …”

Strain-Insensitive, Crosstalk-Suppressed, Ultrawide-Linearity Iontronic Tactile Skin from a Synergistic Segment-Embedded Strategy by Yanchao Zhao (5129174)