Image2_Nanoscaled biphasic calcium phosphate modulates osteogenesis and attenuates LPS-induced inflammation.JPEG by Yi-Chun Su (17473050)

“…Treatment of THP-1-derived macrophages with BCP nanomaterials decreases the expression of various inflammatory genes. …”

DataSheet6_Nanoscaled biphasic calcium phosphate modulates osteogenesis and attenuates LPS-induced inflammation.ZIP by Yi-Chun Su (17473050)

“…Treatment of THP-1-derived macrophages with BCP nanomaterials decreases the expression of various inflammatory genes. …”

Image2_Child-Onset Cerebellar Ataxia Caused by Two Compound Heterozygous Variants in ADPRS Gene: A Case Report.TIF by Jiehui Ma (10792134)

“…</p><p>Conclusion: We present the first report of the existence of two compound heterozygous variants of ADPRS, which leads to CONDSIAS.…”

Image_6_OX40 Expression in Eosinophils Aggravates OVA-Induced Eosinophilic Gastroenteritis.tif by Longwei Xu (655781)

“…</p>Methods<p>Eosinophil infiltration, ovalbumin (OVA)-specific Ig production, OX40 expression and inflammatory factor levels in the intestine and bone marrow (BM) were investigated to evaluate inflammation.</p>Results<p>We confirmed that OVA-challenged mice produced high levels of Ox40, Mbp, Ccl11, Il5, Il4, Il13, and Il6 mRNA and a low level of Ifng mRNA in the intestine. …”

Table 2_Down-regulation of colon mucin production induced by Eimeria pragensis infection in mice.xlsx by Yulia Dwi Setia (21590591)

“…Introduction<p>Eimeria pragensis, an intestinal protozoa infecting mice, induces colitis and reduces goblet cell numbers in the large intestine. In the present study, we investigated the pathogenesis and the mechanisms underlying goblet cell down-regulation in the early phase of infection.…”

A mechanistic use case to support data interoperability across the source to outcome continuum in Environmental Health Science by David Williams (6845183)

“…To accomplish this goal, we develop a pilot use case focused on PM2.5 exposure leading to decreased lung function to identify deficiencies in interoperability, test the functionality of improved standards, and demonstrate the benefits of integrated analyses. …”

Table_1_MED12-Related Disease in a Chinese Girl: Clinical Characteristics and Underlying Mechanism.xls by Chao Wang (146527)

“…While MED12 mutations have been most commonly reported in male patients, we present the case of a 1-year-old girl with clinical characteristics similar to MED12-related disorders. …”

Image1_Ablation Patterns of the Debris Covered Tongue of Halong Glacier Revealed by Short Term Unmanned Aerial Vehicle Surveys.jpeg by Wanqin Guo (450937)

“…However, ice cliffs show the strongest and the most significant ablation rates (averagely 1.36 and 1.22 m w.e. for supraglacial and lateral ice cliffs, respectively), followed by clean ice regions (1.01 m w.e.). …”

Presentation_1_Genome-Wide DNA Methylation Enhances Stemness in the Mechanical Selection of Tumor-Repopulating Cells.pdf by Wei Huang (36889)

“…In 1-day, TRCs had the highest non-CG methylation rate indicating its strong stemness. We found that genes with continuously increasing or decreasing methylation like CREB5/ADAMTS6/LMX1A may also affect the TRC screening process. …”

DataSheet1_Fracture Network Localization Preceding Catastrophic Failure in Triaxial Compression Experiments on Rocks.PDF by Jessica McBeck (11765714)

“…<p>We quantify the spatial distribution of fracture networks throughout six in situ X-ray tomography triaxial compression experiments on crystalline rocks at confining stresses of 5–35 MPa in order to quantify how fracture development controls the final macroscopic failure of the rock, a process analogous to those that control geohazards such as earthquakes and landslides. …”

Table_3_NUF2 overexpression contributes to epithelial ovarian cancer progression via ERBB3-mediated PI3K-AKT and MAPK signaling axes.docx by Ruobing Leng (14288126)

“…NUF2 downregulation decreased cell proliferation, migration, invasion and tumor growth in nude mice. …”

Image_2_OX40 Expression in Eosinophils Aggravates OVA-Induced Eosinophilic Gastroenteritis.tif by Longwei Xu (655781)

“…</p>Methods<p>Eosinophil infiltration, ovalbumin (OVA)-specific Ig production, OX40 expression and inflammatory factor levels in the intestine and bone marrow (BM) were investigated to evaluate inflammation.</p>Results<p>We confirmed that OVA-challenged mice produced high levels of Ox40, Mbp, Ccl11, Il5, Il4, Il13, and Il6 mRNA and a low level of Ifng mRNA in the intestine. …”

DataSheet3_Sanqi Oral Solution Mitigates Proteinuria in Rat Passive Heymann Nephritis and Blocks Podocyte Apoptosis via Nrf2/HO-1 Pathway.zip by Xiaowan Wang (9704207)

“…Further studies showed that SQ treatment could significantly inhibit podocyte apoptosis in PHN rats and ADR-injured podocytes, and protein levels of Cleaved Caspase-3 or the ratio of Bax/Bcl-2 were significantly decreased with SQ treatment in vivo or in vitro. Moreover, we found that the nuclear factor erythroid 2–related factor-2/heme oxygenase 1 (Nrf2/HO-1) pathway mediated the anti-apoptosis effective of SQ in podocyte. …”

Image1_Nanoscaled biphasic calcium phosphate modulates osteogenesis and attenuates LPS-induced inflammation.JPEG by Yi-Chun Su (17473050)

“…Treatment of THP-1-derived macrophages with BCP nanomaterials decreases the expression of various inflammatory genes. …”

Cutaneous Chronic Graft-Versus-Host Disease Does Not Have the Abnormal Endothelial Phenotype or Vascular Rarefaction Characteristic of Systemic Sclerosis by Jo Nadine Fleming (262220)

“…First, there were significantly fewer (p = 0.00001) average vessels in SSc biopsies (9.8) when compared with c-GVHD (16.5). Second, in SSc, endothelial markers were decreased significantly (19/19 and 12/14 for VE cadherin and vWF (p = <0.0001 and <0.05), respectively). …”

Supplementary file 1_Usage, anti-inflammatory effect and safety of adjunctive acupuncture for cerebral infarction: an Apriori algorithm-based data mining and meta-analysis.docx by Fangfei Yu (11906322)

“…</p>Methods<p>We identified qualified randomized controlled trials (RCTs) from eight literature databases. …”

Methylation Landscape of Human Breast Cancer Cells in Response to Dietary Compound Resveratrol by Rubiceli Medina-Aguilar (3161484)

“…Our data showed that resveratrol treatment for 24 h and 48 h decreased gene promoter hypermethylation and increased DNA hypomethylation. …”

Placebo can enhance creativity by Liron Rozenkrantz (4326511)

“…<div><p>Background</p><p>The placebo effect is usually studied in clinical settings for decreasing negative symptoms such as pain, depression and anxiety. …”

Image8_Child-Onset Cerebellar Ataxia Caused by Two Compound Heterozygous Variants in ADPRS Gene: A Case Report.TIF by Jiehui Ma (10792134)

“…</p><p>Conclusion: We present the first report of the existence of two compound heterozygous variants of ADPRS, which leads to CONDSIAS.…”

Syntaxin 4 Eenrichment in β-cells Prevents Conversion to Autoimmune Diabetes in Non-Obese Diabetic (NOD) Mice by Eunjin Oh (10004300)

“…Syntaxin 4 (STX4), a plasma membrane-localized SNARE protein, regulates human islet β-cell insulin secretion and preservation of β-cell mass. We found that human type 1 diabetic (T1D) and non-obese diabetic (NOD) mouse islets show reduced β-cell STX4 expression, consistent with decreased STX4 expression as a potential driver of T1D phenotypes. …”