Phase 2b study of evocalcet (KHK7580), a novel calcimimetic, in Japanese patients with secondary hyperparathyroidism undergoing hemodialysis: A randomized, double-blind, placebo-co... by Tadao Akizawa (316095)

“…Adverse events were observed in 30%–50% of patients (all groups). Incidence of adverse events was similar among all groups except for decreased calcium, which occurred more frequently in the evocalcet 2 mg and cinacalcet groups.…”

IRE1 depletion induces cell cycle arrest independently of apoptosis. by Iratxe Zuazo-Gaztelu (21071939)

Venous ulcer healing treated with conventional therapy and adjuvant laser: is there a difference? by Viviane Maria Osmarin (12688063)

Modeled action potentials at successive nodes of Ranvier in a model myelinated axon. by Charles F. Babbs (430220)

“…In this simulation node width was increased three-fold and paranodal resistance was decreased to one tenth the normal value. Average axon diameter 1.0 micrometer; number of nodes of Ranvier 21; normal node width 0.65 micrometer; injured node width 1.95 micrometer; width of juxtaparanodal region on both sides of a node 5.0 micrometers. …”

Cnot4 Het does not affect mRNA expression of metabolic genes as well as serum lipid levels or glucose tolerance. by Tomokazu Yamaguchi (8284989)

Cnot4 mediates differentiation into adipocytes from mouse embryonic fibroblasts. by Tomokazu Yamaguchi (8284989)

Nicotine as a Catalyst for Chlorination Promoted by Hypochlorous Acid: Experimental and Theoretical Studies by Valdecir F. Ximenes (471290)

Orientation Control and Crystallization in a Soft Confined Phase Separated Block Copolymer by Lamiaa G. Alharbe (3704986)

“…The orientation process and subsequent crystallization behavior were investigated <i>in situ</i> as a function of temperature by AFM. Fully confined crystallization was observed within the range 25–50 °C, with templated and breakout crystallization observed at higher crystallization temperature. …”

Glyphosate alters the composition, but not density, of the <i>A</i>. <i>gambiae</i> midgut microbiota. by Daniel F. Q. Smith (10788903)

“…Error bars represent the mean and ±SD. <b>(B)</b> Glyphosate alters the composition of the mosquito microbiota, leading to decrease of Entereobacteriacae and an increase of <i>Asaia</i> spp. …”

Disease course of Chronic Relapsing Inflammatory Optic Neuropathy (CRION) in a single care center by Luis Enrique MOLINA-CARRIÓN (12687286)

“…Currently, all patients are on maintenance treatment with mycophenolate mofetil or rituximab with a decrease in relapsing rate. Conclusions: Diagnosis of CRION is challenging and should be kept in mind. …”

A Feedback Loop between Dynamin and Actin Recruitment during Clathrin-Mediated Endocytosis by Marcus J. Taylor (173337)

“…Conversely, acute ablation of actin dynamics using latrunculin-B led to a ∼50% decrease in the incidence of scission, an ∼50% decrease in the amplitude of dynamin recruitment, and abolished actin and N-BAR recruitment to scission events. …”

Relevant epidemiological metrics in England over the course of the pandemic. by Siyu Chen (278663)

Data_Sheet_1_Association Between Plasma Exosomes S100A9/C4BPA and Latent Tuberculosis Infection Treatment: Proteomic Analysis Based on a Randomized Controlled Study.docx by Ying Du (42066)

“…Eligible participants for both screening and verification sets were randomly selected from the based-RCT in a 1:1 ratio by age and gender. Reversion was defined as a decrease in IFN-γ levels from >0.70 IU/ml prior to treatment to 0.20 IU/ml within 1 week of treatment. …”

Data_Sheet_2_Association Between Plasma Exosomes S100A9/C4BPA and Latent Tuberculosis Infection Treatment: Proteomic Analysis Based on a Randomized Controlled Study.docx by Ying Du (42066)

“…Eligible participants for both screening and verification sets were randomly selected from the based-RCT in a 1:1 ratio by age and gender. Reversion was defined as a decrease in IFN-γ levels from >0.70 IU/ml prior to treatment to 0.20 IU/ml within 1 week of treatment. …”

The COPI-Mediated Retrograde Trafficking Pathway Is a Negative Regulator of Lipid Storage by Mathias Beller (269148)

Supplementary file 1_Improved mental health outcomes and normalised spontaneous EEG activity in veterans reporting a history of traumatic brain injuries following participation in... by Grace Blest-Hopley (10663945)

“…</p>Results<p>Improvements were observed across several mental health measures: PTSD (PCL-5 scores decreased by 50%, p=0.010), depression (PHQ-9 scores decreased by 65%, p<0.001), and anxiety (STAI) scores decreased by 28%, p<0.001). …”

Supplementary file 2_Improved mental health outcomes and normalised spontaneous EEG activity in veterans reporting a history of traumatic brain injuries following participation in... by Grace Blest-Hopley (10663945)

“…</p>Results<p>Improvements were observed across several mental health measures: PTSD (PCL-5 scores decreased by 50%, p=0.010), depression (PHQ-9 scores decreased by 65%, p<0.001), and anxiety (STAI) scores decreased by 28%, p<0.001). …”

Analysis of tumour vasculature with the addition of more USMB groups. by Deepa Sharma (278210)

“…The vasculature becomes less evident in the treated groups, with decreasing numbers of stained blood vessels. Images were taken at a 20x objective lens, and the scale bar denotes ~50μm. …”

Box plots reflecting the change in the difference between the DPOAE and the noise floor at all frequencies in the right ear. by Jessica Paken (10677168)

Box plots reflecting the change in the difference between the DPOAE and the noise floor at all frequencies in the left ear. by Jessica Paken (10677168)