DEGs in transcriptome of virulent CN-Bx1 and avirulent US-Bx1. from Enhancement of oxidative stress contributes to increased pathogenicity of the invasive pine wood nematode by Wei Zhang (405)

“…Increased expression of <i>Mn-SOD</i> and reduced expression of <i>catalase</i>/<i>GPX-5</i> and H₂O₂ accumulation during invasion are associated with virulent strains. …”

Platinum-Catalyzed Direct Amination of Allylic Alcohols under Mild Conditions: Ligand and Microwave Effects, Substrate Scope, and Mechanistic Study by Takashi Ohshima (1295094)

“…The choice of the ligand was crucial toward achieving high catalytic activity, and we demonstrated that not only the large bite-angle but also the linker oxygen atom of the Xantphos and DPEphos ligands was highly important. …”

Image_1_Oxytocin accelerates tight junction formation and impairs cellular migration in 3D spheroids: evidence from Gapmer-induced exon skipping.tif by Benjamin Jurek (322560)

“…OXTR truncation differentially activated intracellular signaling cascades related to cell-cell attachment and proliferation like Akt, ERK1/2-RSK1/2, HSP27, STAT1/5, and CREB, as assessed by a Kinase Profiler Assay. …”

Subgroup analysis. by Xuan Zhou (329338)

“…Subgroup analysis showed a negative association between the albumin infusion and sepsis risk in the AP patients with serum albumin ≤ 3.5g/L (adjusted OR=0.29, 95%CI = 0.08–0.77).</p><p>Conclusion</p><p>In this study, we found an association between albumin administration and a lower risk of sepsis in AP patients, which persisted after multivariate adjustment. …”

Image_2_PLAU Promotes Cell Proliferation and Epithelial-Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma.TIF by Guangjin Chen (1989892)

“…Besides, genes associated with PLAU were also enriched in EMT pathways. We further validated the bioinformatics analysis results by in vivo and in vitro experiments. …”

A hotspot for threatened Mediterranean odonates in the Seybouse River (Northeast Algeria): are IUCN population sizes drastically underestimated? by Rassim Khelifa (2867750)

“…To obtain reliable estimations of the population size and distribution of three threatened species, <i>Calopteryx exul</i>, <i>Coenagrion mercuriale</i>, and <i>Gomphus lucasii</i>, we first conducted capture-mark-recapture in a natural population during one flight season, and second we carried out intensive sampling of adults, larvae and exuviae in the Seybouse watershed, Northeast Algeria. …”

DNA Repair and Cell Cycle Biomarkers of Radiation Exposure and Inflammation Stress in Human Blood by Helen Budworth (121329)

“…<div><p>DNA damage and repair are hallmarks of cellular responses to ionizing radiation. We hypothesized that monitoring the expression of DNA repair-associated genes would enhance the detection of individuals exposed to radiation versus other forms of physiological stress. …”

Video_1_Minimizing Guidewire Unwilling Passage and Related Perforation During Transradial Procedures: Prevention Is Better Than Cure.WMV by Lili Xu (257856)

“…Afterwards we included 239 patients and randomized them according to a random number table to either the unmodified or the knuckle guidewire to further confirm the efficiency and safety of knuckle guidewire advancement.…”

Characterization of the Ti Kβ spectral profile by C T Chantler (557430)

“…The peak energy of the titanium Kβ spectral profile is found to be 4931.966 ± 0.022 eV prior to instrumental broadening. This 4.5 ppm result decreases the uncertainty over the past literature by a factor of 2.6 and is 2.4 standard deviations from the previous standard. …”

Simulations show that microSLAM improves power and false positive rates. by Miriam Goldman (21433180)

“…<p><b>A)</b> The false positive rates of the τ test of microSLAM were estimated using simulations with varying GRMs but no trait associations. We simulated gene presence/absence and GRMs for the 1000 iterations (τ test simulation 1; Methods). …”

DataSheet_1_Single-cell RNA sequencing combined with whole exome sequencing reveals the landscape of the immune pathogenic response to chronic mucocutaneous candidiasis with STAT1... by Xiaodi Lu (13796016)

“…In our review of the literature on signal transducer and activator of transcription 1 gain-of-function (c.Y289C) mutations, we identified seven cases in total. The median age of onset for CMC (n=4, data lacking for three cases) was 10.5 years (range: birth to 11 years), with an average onset age of 8 years. …”

Table_1_The Presence of a CMV Immunodominant Allele in the Recipient Is Associated With Increased Survival in CMV Positive Patients Undergoing Haploidentical Hematopoietic Stem Cel... by Dolores Grosso (7391423)

“…In this retrospective, multivariable review of 216 HI HSCT patients, we found that CMV+ recipients possessing at least 1 of 5 identified CMV IMD alleles had a lower hazard of death (HR = 0.40, p = 0.003) compared to CMV+ recipients not possessing a CMV IMD allele, and an overall survival rate similar to their CMV– counterparts. …”

Image_6_Apolipoprotein-E deficiency leads to brain network alteration characterized by diffusion MRI and graph theory.JPEG by Margaret Caroline Stapleton (17437713)

“…We investigated the brain network structure in adult ApoE knock out (ApoE KO) and wild-type (WT) mice with diffusion tensor imaging (DTI) followed by graph theory to delineate brain network topology. …”

Differences in pathogenicity of three animal isolates of <i>Mycobacterium</i> species in a mouse model by Haodi Dong (4390237)

“…To test the hypothesis that different species of pathogenic mycobacteria isolated from varied anatomic locations or animal species differ in virulence and pathogenicity, we performed experiments with three mycobacteria strains (NTSE-3(MTB), NTSE-4(MBO) and NTSE-5 (MAV)) obtained from animal species. …”

Table7_Comprehensive Analysis of the Transcriptome-Wide m6A Methylation Modification Difference in Liver Fibrosis Mice by High-Throughput m6A Sequencing.XLSX by Chang Fan (5305073)

“…In an additional cell experiment, we also observed that the decreased expression of WTAP induced the development of LF as a result of promoting hepatic stellate cell (HSC) activation. …”

Image 1_Metabolic readouts of tumor instructed normal tissues (TINT) identify aggressive prostate cancer subgroups for tailored therapy.tif by Ilona Dudka (8857529)

“…The levels of six metabolites differentiated between the two groups; myo-inositol, lysine, serine and combined signal of lysine/leucine/arginine were increased in benign samples near high-grade tumors (B ISUP 3 + 4) compared to near low-grade tumors (B ISUP 1 + 2), while levels of ethanolamine and lactate were decreased. Additionally, we revealed metabolic differences in non-cancer tissues as a function of their distance to the nearest tumor. …”

Data_Sheet_4_Alternative Mating Tactics in Socially Monogamous Prairie Voles, Microtus ochrogaster.pdf by Stephen M. Shuster (629138)

“…We found that: (1) the average fitnesses of males and females within each population were identical when adjusted by the sex ratio; (2) the variance in fitness in male and female prairie voles was comparable to that of highly polygynous species; (3) The average fitnesses of male tactics, and of female tactics, were equivalent within and among years within each location; (4) consistent with negative frequency-dependent selection acting on mating phenotypes, the between-tactic variance in fitness for male and female mating tactics decreased with increasing study duration; (5) consistent with negative assortative mating, resident males, and wanderer females produced offspring primarily in monogamous partnerships, whereas wanderer males and resident females produced offspring primarily in polygamous partnerships. …”

Voltammetric Scanning Electrochemical Cell Microscopy: Dynamic Imaging of Hydrazine Electro-oxidation on Platinum Electrodes by Chang-Hui Chen (1497196)

Image 1_Impact of social factors and health campaigns on the burden of idiopathic epilepsy: an inequality, decomposition, generalized and synthetic difference-in-differences study.... by Xuewen Rong (6242657)

“…The slope index of inequality for the mortality burden decreased from 1.97 to 1.62. After the policy shock, the age-standardized rate (ASR) of years lived with disability (YLD) in the Caribbean increased significantly to 4.59 (95% CI: 0.96 to 8.22), while the all-age YLD rate in the U.S. increased (5.18, 95% CI: 0.66 to 9.70) for both sexes.…”

Choice of link noise threshold. by Daniel B. Larremore (469095)

“…Choosing a tolerance for false positives (grey line) specifies a minimum retained block length; since blocks are of integer length, the next largest integer is the minimum retained block length (squares). Curves for HVRs 3 and 5 are plotted, for which we would select thresholds of five and seven, respectively. …”