Palmitoylation inhibitors impair APP dimerization in CHO cells. by Raja Bhattacharyya (3359186)

“…Quantitation showed 54 and 58% decrease of APP-APP dimerization by cerulenin (25 μg/ml) and 2-BP (50 μM), respectively. …”

Image1_Proanthocyanidins isolated from the leaves of Ficus glomerata evaluated on the activities of rumen enzymes: in vitro and in silico studies.PNG by Suman Lata (369115)

“…Additionally, both compounds led to a decrease in protease activity with increasing incubation time and concentration. …”

Decline in SHP2 activity follows decline in ARSB in HepG2 cells and in ARSB-null mice. by Sumit Bhattacharyya (14205)

“…<p><b>(A)</b> The SHP2 activity declined ~36% from (2.49 ± 0.15 nmol/mg protein/0.5 h to 1.59 nmol/mg protein/0.5h) following ARSB silencing (p<0.001; n = 6), and increased to 3.70 ± 0.16 nmol.mg protein/0.5h when ARSB was overexpressed in the HepG2 cells (p<0.001; n = 3). …”

Image2_Proanthocyanidins isolated from the leaves of Ficus glomerata evaluated on the activities of rumen enzymes: in vitro and in silico studies.JPEG by Suman Lata (369115)

“…Additionally, both compounds led to a decrease in protease activity with increasing incubation time and concentration. …”

DataSheet3_Proanthocyanidins isolated from the leaves of Ficus glomerata evaluated on the activities of rumen enzymes: in vitro and in silico studies.docx by Suman Lata (369115)

“…Additionally, both compounds led to a decrease in protease activity with increasing incubation time and concentration. …”

Sera selected from national STI surveillance system shows <i>Chlamydia trachomatis</i> PgP3 antibody correlates with time since infection and number of previous infections by Paula B. Blomquist (6061163)

“…With the double-antigen ELISA, the increase was from 61.1% (95%CI: 53.2–60.7) to 97.0% (95%CI: 88.5–99.3). Seropositivity decreased with time since CT diagnosis on only the indirect assay, to 49.3% (95%CI: 40.9–57.7) two or more years after a first diagnosis and 51.9% (95%CI: 33.2–70.0) after a repeat diagnosis.…”

STOX1A induces changes in several major cell cycle regulatory genes. by Daan van Abel (214754)

“…<p>(A) The effect of stable STOX1A overexpression in the SH-SY5Y neuroblastoma cell line on four major mammalian cell cycle regulatory genes was determined with quantitative RT-PCR showing a mean 1,4 fold (mean ΔΔCt is −0,49) and mean 1,72 fold (mean ΔΔCt is −0,78) increased mRNA expression for CCNA2 and CCNB1, respectively, and a mean 1,22 fold (mean ΔΔCt is −0,29) decreased mRNA expression for CCNC in STOX1A stably transfected cell compared to their negative controls. …”

Antitumor Activity and Induction of TP53-Dependent Apoptosis toward Ovarian Clear Cell Adenocarcinoma by the Dual PI3K/mTOR Inhibitor DS-7423 by Tomoko Kashiyama (162572)

“…Here, we describe the anti-tumor effect of DS-7423 on a panel of nine OCCA cell lines. IC₅₀ values for DS-7423 were <75 nM in all the lines, regardless of the mutational status of <i>PIK3CA</i>. …”

High Out-of-pocket Health Care Cost Burden Among Medicare Beneficiaries With Diabetes, 1999–2017 by Joohyun Park (1366980)

“…</p> <p><b>Results </b></p> <p>Total OOP costs were $3,609 to $5,283, with significant increases until 2005 followed by a leveling off. …”

DataSheet8_Mogrol Attenuates Osteoclast Formation and Bone Resorption by Inhibiting the TRAF6/MAPK/NF-κB Signaling Pathway In vitro and Protects Against Osteoporosis in Postmenopau... by Yongjie Chen (269938)

“…Furthermore, RT–PCR indicated that mogrol suppressed osteoclastogenesis-related gene expression, including CTSK, ACP5, MMP9 and DC-STAMP, in RANKL-induced bone marrow macrophages Western blotting demonstrated that mogrol suppressed osteoclast formation by blocking TNF receptor-associated factor 6 (TRAF6)-dependent activation of the mitogen-activated protein kinase nuclear factor-B (NF-κB) signaling pathway, which decreased two vital downstream transcription factors, the nuclear factor of activated T cells calcineurin-dependent 1 (NFATc1) and c-Fos proteins expression. …”

DataSheet7_Mogrol Attenuates Osteoclast Formation and Bone Resorption by Inhibiting the TRAF6/MAPK/NF-κB Signaling Pathway In vitro and Protects Against Osteoporosis in Postmenopau... by Yongjie Chen (269938)

“…Furthermore, RT–PCR indicated that mogrol suppressed osteoclastogenesis-related gene expression, including CTSK, ACP5, MMP9 and DC-STAMP, in RANKL-induced bone marrow macrophages Western blotting demonstrated that mogrol suppressed osteoclast formation by blocking TNF receptor-associated factor 6 (TRAF6)-dependent activation of the mitogen-activated protein kinase nuclear factor-B (NF-κB) signaling pathway, which decreased two vital downstream transcription factors, the nuclear factor of activated T cells calcineurin-dependent 1 (NFATc1) and c-Fos proteins expression. …”

The SNAP Cycle and Diabetes Management During a One-Time Change in Disbursement Schedule by Sabrina K. Young (12529594)

Supplementary Material for: Blood Pressure Variability in Fabry Disease Patients by Dincer M.T. (9984839)

A bio-inspired robotic climbing robot to understand kinematic and morphological determinants for an optimal climbing gait by Christofer Clemente (6437156)

Quantitative electroencephalography in children with attention deficit hyperactivity disorder and healthy children: Behavioral and age correlates by Nezla S. Duric (17623426)

An example of subnetworks which influence reliability. by Aaditya V. Rangan (305264)

Reproductive ecology and territorial behavior of Boana goiana (Anura: Hylidae), a gladiator frog from the Brazilian Cerrado by Tailise M. Dias (9224835)

Nilotinib induces apoptosis and cell cycle arrest in HEI-193 cells at clinically-relevant concentrations. by Nesrin Sabha (127278)

“…(C) In GM, the proportion of cells in G1-phase is increased and the proportion in G2/M decreased at ≥5 µM nilotinib. Shown, mean of two replicate experiments.…”

Table_1_Oleanolic Acid Mitigates 6-Hydroxydopamine Neurotoxicity by Attenuating Intracellular ROS in PC12 Cells and Striatal Microglial Activation in Rat Brains.DOCX by Zama N. P. Msibi (7292738)

DataSheet1_Whole-Genome Sequencing of Sinocyclocheilus maitianheensis Reveals Phylogenetic Evolution and Immunological Variances in Various Sinocyclocheilus Fishes.docx by Ruihan Li (6611660)

“…We obtained a genome assembly of 1.7 Gb with a scaffold N50 of 1.4 Mb and a contig N50 of 24.7 kb. …”