Fusion-Activated Ca²⁺ Entry: An “Active Zone” of Elevated Ca²⁺ during the Postfusion Stage of Lamellar Body Exocytosis in Rat Type II Pneumocytes by Pika Miklavc (247760)

“…</p><h3>Methodology/Principal Findings</h3><p>We studied isolated rat alveolar type II cells using previously developed imaging techniques. …”

image1_Neuroprotective and Neurorescue Mode of Action of Bacopa monnieri (L.) Wettst in 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Induced Parkinson’s Disease: An In Silico and I... by Babita Singh (811405)

“…Wettst (Brahmi) has been used in Indian Ayurvedic medicine to enhance memory and intelligence. Herein, we assessed the neuroprotective role of Bacopa monnieri (L.) …”

Model of box C/D scaRNP 2, 9 and 17 biogenesis. by Isioma I. Enwerem (722072)

“…Based on the data presented here, we believe that coilin, WRAP53 and SMN all participate at regulating the flux of scaRNA 2, 9 and 17 distribution and processing. …”

Data_Sheet_1_Health-related heterogeneity in brain aging and associations with longitudinal change in cognitive function.docx by Jo Wrigglesworth (6563171)

“…Among resilient brain agers, class 1 was associated with a decrease in cognition, and class 2 with an increase over 5 years, though was a small effect that was equivalent to a 0.04 standard deviation difference per year. …”

Table 4_Global burden and trends of norovirus-associated diseases from 1990 to 2021 an observational trend study.xlsx by MengLan Zhu (20517257)

“…For trend analysis, we employed annual percentage change (EAPC) through linear regression and applied Joinpoint analysis to identify significant changes over time. …”

Differential DNA methylation of <i>MSI2</i> and its correlation with diabetic traits by Jae-Pil Jeon (4044923)

“…In human pancreatic islets, at the single-base resolution (using whole-genome bisulfite sequencing), the 292 CpG sites in the ±5kb at chr17:55484635 were found to be significantly hypo-methylated in donors with T2D (average decrease = 13.91%, 95% confidence interval (CI) = 4.18~ 17.06) as compared to controls, and methylation patterns differed by sex (-9.57%, CI = -16.76~ -6.89) and age (0.12%, CI = -11.17~ 3.77). …”

Table_3_Photosynthetic Carbon Fixation and Sucrose Metabolism Supplemented by Weighted Gene Co-expression Network Analysis in Response to Water Stress in Rice With Overlapping Grow... by Xinpeng Wang (4611307)

“…The results showed that short-term drought stress promoted photosynthetic carbon fixation. However, ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) activity significantly decreased, resulting in a significant decrease in photosynthetic rate. …”

Table_2_Photosynthetic Carbon Fixation and Sucrose Metabolism Supplemented by Weighted Gene Co-expression Network Analysis in Response to Water Stress in Rice With Overlapping Grow... by Xinpeng Wang (4611307)

“…The results showed that short-term drought stress promoted photosynthetic carbon fixation. However, ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) activity significantly decreased, resulting in a significant decrease in photosynthetic rate. …”

Qatar’s immigrants at higher risk of diabetes by Nature Research (16552612)

“…The researchers stress, however, that their preliminary results should be confirmed in future studies involving larger numbers of participants. 1 “We would advise the Qatari government to screen all immigrants entering the country, as this would decrease the risk of unnecessary complications due to the late diagnosis of diabetes,” says lead author Dennis Mook-Nakamori. …”

Fig 1 - by Kushank Bajaj (7421042)

“…No effect on climate impact is considered when domestic impact and consumption impact are close to each other, where close is defined based on the lowest 5th percentile of the shortest distance between each point on the plot and the 1:1 line. …”

Image 8_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpeg by Eisa Mahyari (9681962)

“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27^pos), AS+AAU (HLA-B27^pos), AAU (HLA-B27^pos), HCs (HLA-B27^pos), and HCs (HLA-B27^neg); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”

<b>Ectomycorrhizal trees rely on nitrogen resorption less than arbuscular mycorrhizal trees globally</b> by Bai Liu (17306110)

Random Lasing in ZnO Nanopowders Based on Multiphoton Absorption for Ultrafast Upconversion Application by Jiao Tian (583054)

“…This study reports ultraviolet picosecond random lasing (RL) based on multiphoton absorption in zinc oxide (ZnO) nanopowders with a mean size of ∼100 nm under femtosecond optical excitation. …”

Lizards learn a spatial task in a closed-loop automated paradigm. by Tal Eisenberg (18078801)

“…Notice the strong increase for the third area (blue) and strong decrease for the second area. <b>(F)</b> Position trajectories over a single day (animal 1, block 3, day 3), segmented into stationary (gray dots marking mean location during stationary periods) and movement periods (colored lines). …”

Down-regulation of IRP1 expression and IRP1 activities in mouse macrophages exposed to paraquat (PQ). by Anna Milczarek (4036724)

“…<b>(D)</b> IRP1 aconitase activity (means ± S.D. n = 5 biological experiments) determined spectrophotometrically in hepatic cytosolic extracts by measuring the disappearance of <i>cis</i>-aconitate at 240 nm as described previously [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0176800#pone.0176800.ref012" target="_blank">12</a>]. …”

Mitochondrial Ca²⁺ uptake contributes to cell death induced by Aβ oligomers. by Sara Sanz-Blasco (271498)

“…Cells were loaded with TMRM 10 nM and mitochondrial depolarization was estimated by the decrease in TMRM fluorescence. Pictures show TMRM fluorescence images of cerebellar granule cells treated for 5 min with vehicle (control), 100 nM FCCP or 10 µM FCCP. …”

Table_3_Effect of Wii Fit Exercise With Balance and Lower Limb Muscle Strength in Older Adults: A Meta-Analysis.DOCX by Haoyan Liu (10779576)

“…The methodologic quality of the included studies evaluated with the PEDro average score was 6.4 and ranged from 5 to 8 points, indicating moderate quality. Compared with no exercise, Wii Fit exercise was associated with significant improved scores on the Berg Balance Scale, which evaluates functional balance (mean difference, 1.38; 95% CI, 0.61–2.16; I² = 31%; P = 0.0005) and on the Timed Up and Go test, which evaluates static and dynamic balance (standardized mean difference, −0.51; 95% CI,−0.88 to −0.14; I² = 52%; P = 0.007). …”

Data_Sheet_1_Effect of Wii Fit Exercise With Balance and Lower Limb Muscle Strength in Older Adults: A Meta-Analysis.docx by Haoyan Liu (10779576)

“…The methodologic quality of the included studies evaluated with the PEDro average score was 6.4 and ranged from 5 to 8 points, indicating moderate quality. Compared with no exercise, Wii Fit exercise was associated with significant improved scores on the Berg Balance Scale, which evaluates functional balance (mean difference, 1.38; 95% CI, 0.61–2.16; I² = 31%; P = 0.0005) and on the Timed Up and Go test, which evaluates static and dynamic balance (standardized mean difference, −0.51; 95% CI,−0.88 to −0.14; I² = 52%; P = 0.007). …”

Hypoxia activates autophagy in CD8 T cells. by Katelin N. Townsend (501754)

“…(B) Autophagy induction is shown by quantification of decreasing p62 levels without chloroquine (CQ) treatment and (C) LC3-II accumulation with CQ treatment under normoxia (norm) or 1.5% oxygen (hyp). …”

Table_1_Age-Related Structural and Functional Changes in the Mouse Lung.DOCX by Henri Schulte (8078324)

“…While the alveolar number decreased from young (7.5 × 10⁶) to middle-aged (6 × 10⁶) and increased again in old (9 × 10⁶) mice, the mean alveolar volume and mean septal surface area per alveolus conversely first increased in middle-aged and then declined in old mice. …”