C2GnT1 gene knockdown decreases C2-O-sLe^X glycoproteins and C2GnT1 activity. by Catherine A. St. Hill (357388)

“…Note the absence of a detected C2GnT1 protein 50 kDa band. (D) We observed a 30–40% decrease in reactivity with CHO-131 mAb by flow cytometry for LS174T and HepG2 cells that contained C2GnT1 shRNA. …”

Analysis of parasites expressing ddFKBPmyc-Rab5A(N158I) and ddFKBPmyc-Rab5C(N153I). by Katrin Kremer (386602)

Design, Synthesis, and Biological Evaluation of Indoline and Indole Derivatives as Potent and Selective α_1A-Adrenoceptor Antagonists by Fei Zhao (183673)

“…In this study, two highly selective and potent α_1A-AR antagonists, compounds (<i>R</i>)-<b>14r</b> (IC₅₀ = 2.7 nM, α_1B/α_1A = 640.1, α_1D/α_1A = 408.2) and (<i>R</i>)-<b>23l</b> (IC₅₀ = 1.9 nM, α_1B/α_1A = 1506, α_1D/α_1A = 249.6), which exhibited similar activities and better selectivities in cell-based calcium assays as compared with the marketed drug silodosin (IC₅₀ = 1.9 nM, α_1B/α_1A = 285.9, α_1D/α_1A = 14.4), were identified. …”

Excel spreadsheet containing, in separate sheets (for each figure), the underlying numerical datas for Figure panels 1A, 1B, 1C, 2B, 3A, 3B, 3C, 4C, 4D, 4E, 4F, 4G, 5B, 8C and 8D. by Acharya Balkrishna (5640038)

Supplementary Material for: Inverse and Direct Cancer Comorbidity in People with Central Nervous System Disorders: A Meta-Analysis of Cancer Incidence in 577,013 Participants of 50... by Catalá-López F. (4142920)

“…<b><i>Results:</i></b> The presence of CNS disorders was associated with a reduced co-occurrence of cancer (ES = 0.92; 95% confidence interval, CI: 0.87-0.98; I² = 94.5%). …”

Analysis of replication at unique origins. by Kelsey L. Lynch (7465649)

(A) FC and VIP bubble plots of the Model.vs.SHR; (B) Hierarchical clustering results of differential metabolites in the Model.vs.SHR (only the top 50 metabolites with the highest V... by Xiao Zhang (152326)

Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G_q, G₁₁, and β-arrestin2) coupled to 5-HT_2A receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”

Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G_q, G₁₁, and β-arrestin2) coupled to 5-HT_2A receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”

R₇-fused peptides inhibit FMDV production in BHK-21 cells. by Mónica González-Magaldi (638526)

Lysosome function, as assessed by Lamp1 levels, are unchanged in the <i>GBA1</i> D409V KI mouse model. by Nicole K. Polinski (10947787)

Introduction of the D409V point mutation to the <i>GBA1</i> gene does not affect <i>GBA1</i> mRNA transcription or GCase protein translation. by Nicole K. Polinski (10947787)

Characteristics of participants and prevalence of workplace violence and types per 100 Healthcare workers. by Javier A. Flores-Cohaila (16933983)

Effect sizes on the Poisson multivariate regression with and without propensity score matching in healthcare workers, doctors/physicians, and nurses. by Javier A. Flores-Cohaila (16933983)

Supplementary table 1. by Javier A. Flores-Cohaila (16933983)

“…<div><p>Introduction</p><p>The prevalence of workplace violence in healthcare is 50–60%. While it has been linked to decreased job satisfaction, diminished quality of care, and economic burdens on healthcare systems, there are still major gaps. …”

Prevalence and 95% Confidence Intervals of depressive symptoms, burnout, sleep problems, work-life balance, and intention to quit in Peruvian physicians and nurses. by Javier A. Flores-Cohaila (16933983)

Comparison of the covariates after propensity score matching. by Javier A. Flores-Cohaila (16933983)

Participant selection flowchart. by Javier A. Flores-Cohaila (16933983)

“…<div><p>Introduction</p><p>The prevalence of workplace violence in healthcare is 50–60%. While it has been linked to decreased job satisfaction, diminished quality of care, and economic burdens on healthcare systems, there are still major gaps. …”

Association of SDOH scores with attitudes, practices and mental health outcomes among Arkansans overall and by race and ethnicity ^a^,^b^,<s... by Jenil R. Patel (3639451)

We added a Pdf document with the supplementary Figures and captions from The influence of sea ice, wind speed and marine mammals on Southern Ocean ambient sound by Sebastian Menze (749188)