Table5_Characterization of exogenous αSN response genes and their relation to Parkinson’s disease using network analyses.XLSX by Zahra Nayeri (8837267)

“…<p>Despite extensive research, the molecular mechanisms underlying the toxicity of αSN in Parkinson’s disease (PD) pathology are still poorly understood. To address this, we used a microarray dataset to identify genes that are induced and differentially expressed after exposure to toxic αSN aggregates, which we call exogenous αSN response (EASR) genes. …”

The presence of B cells promotes cellular expansion and CD4⁺ T cell proliferation in the lung of mice with chronic TB. by Yong Chen (109188)

TRPC channels modulate the vesicle replenishment rate and the RRP size. by Yvonne Schwarz (7406756)

“…<p>(A) Exemplary EPSCs triggered by HFS (20 Hz, 40 AP/2 s) of autaptic wt and TRPC1/C4/C5 tko neurons (inset magnified view on the first 4 EPSCs of the train response. …”

TRPC channels regulate Ca²⁺-signaling and short-term plasticity of fast glutamatergic synapses by Yvonne Schwarz (7406756)

“…Specifically, loss of TRPC1/C4/C5 channels decreases basal-evoked secretion, reduces the pool size of readily releasable vesicles, and accelerates synaptic depression during high-frequency stimulation (HFS). …”

TRPC channels augment the presynaptic Ca²⁺-rise upon HFS. by Yvonne Schwarz (7406756)

“…(D) Maximum ΔF/F₀ from the data shown in (C), tko, <i>p</i> = 0.006; +C1, <i>p</i> = 0.0076; +C5, <i>p</i> = 0.0023. (E) TRPC deficiency decreases, whereas TRPC expression increases the slope of ΔF/F₀ during HFS (slope between the 6th and the 13th data point; tko, <i>p</i> = 0.003; +C1, <i>p</i> = 0.035; +C5, <i>p</i> = 0.002. …”

Effect of downregulation of <i>Pf</i>HtrA2 levels on mitochondrial oxidative stress and mitochondrial membrane potential. by Shweta Singh (409313)

The Deoxyhypusine Synthase Mutant <i>dys1-1</i> Reveals the Association of eIF5A and Asc1 with Cell Wall Integrity by Fabio Carrilho Galvão (396804)

“…In this study, we generated and characterized the <i>dys1-1</i> mutant, which showed a strong depletion of mutated Dys1 protein, resulting in more than 2-fold decrease in hypusine levels relative to the wild type. …”

Increased CD4⁺CXCR5⁺T follicular helper cells in diabetic nephropathy by Nan Zhang (46264)

“…Post-treatment, there was a significant reduction in the CD4⁺CXCR5⁺PD-1⁺ Tfh cell counts and its subsets, with a corresponding decrease in plasma levels of IL-6 and IL-17A (<i>p</i> < 0.05) in DN patients, as compared to the HCs. …”

The Spatial Dynamics of Dengue Virus in Kamphaeng Phet, Thailand by Piraya Bhoomiboonchoo (628511)

“…Significant clustering was observed up to 5 km. We found a steadily decreasing trend in the correlation in epidemics curves by distance: communities separated by up to 5 km had a mean correlation of 0.28 falling to 0.16 for communities separated between 20 km and 25 km. …”

Table_5_Distribution of Meiofauna in Bathyal Sediments Influenced by the Oxygen Minimum Zone Off Costa Rica.DOCX by Carlos Neira (2914346)

Image_5_Evolutionary history of genus Coptis and its dynamic changes in the potential suitable distribution area.jpeg by Yiheng Wang (5448683)

“…The most suitable climatic conditions for Coptis were as follows: precipitation of driest quarter > 25.5 mm, annual precipitation > 844.9 mm and annual mean temperature -3.1 to 19 °C. …”

DataSheet_1_SARS-CoV-2-Specific IgG and IgA response in maternal blood and breastmilk of vaccinated naïve and convalescent lactating participants.docx by Yesica Longueira (13896795)

“…</p>Methods<p>Here, we evaluated anti-SARS-CoV-2 IgG and IgA levels in both serum and milk samples using a longitudinal and a cross-sectional cohort of 208 breastfeeding vaccinated women from Argentina with or without previous SARS-CoV-2 infection.…”

Percent cover of <i>S</i>. <i>pacifica</i> (top row) and subordinate species (bottom row) at high, medium and low elevations (left to right). by Akana E. Noto (3623366)

Table_4_Aneuploidy enables cross-tolerance to unrelated antifungal drugs in Candida parapsilosis.DOCX by Liu-liu Sun (15205327)

“…In clinical isolates, tolerance to echinocandins in Candida species is mostly due to point mutations of FKS genes, which encode the target protein of echinocandins. However, here, we found chromosome 5 trisomy was the major mechanism of adaptation to the echinocandin drug caspofungin, and FKS mutations were rare events. …”

Table_2_Aneuploidy enables cross-tolerance to unrelated antifungal drugs in Candida parapsilosis.DOCX by Liu-liu Sun (15205327)

“…In clinical isolates, tolerance to echinocandins in Candida species is mostly due to point mutations of FKS genes, which encode the target protein of echinocandins. However, here, we found chromosome 5 trisomy was the major mechanism of adaptation to the echinocandin drug caspofungin, and FKS mutations were rare events. …”

Table_3_Aneuploidy enables cross-tolerance to unrelated antifungal drugs in Candida parapsilosis.XLSX by Liu-liu Sun (15205327)

“…In clinical isolates, tolerance to echinocandins in Candida species is mostly due to point mutations of FKS genes, which encode the target protein of echinocandins. However, here, we found chromosome 5 trisomy was the major mechanism of adaptation to the echinocandin drug caspofungin, and FKS mutations were rare events. …”

Image_1_Aneuploidy enables cross-tolerance to unrelated antifungal drugs in Candida parapsilosis.TIF by Liu-liu Sun (15205327)

“…In clinical isolates, tolerance to echinocandins in Candida species is mostly due to point mutations of FKS genes, which encode the target protein of echinocandins. However, here, we found chromosome 5 trisomy was the major mechanism of adaptation to the echinocandin drug caspofungin, and FKS mutations were rare events. …”

Table_1_Aneuploidy enables cross-tolerance to unrelated antifungal drugs in Candida parapsilosis.DOCX by Liu-liu Sun (15205327)

“…In clinical isolates, tolerance to echinocandins in Candida species is mostly due to point mutations of FKS genes, which encode the target protein of echinocandins. However, here, we found chromosome 5 trisomy was the major mechanism of adaptation to the echinocandin drug caspofungin, and FKS mutations were rare events. …”

Image_3_Aneuploidy enables cross-tolerance to unrelated antifungal drugs in Candida parapsilosis.TIF by Liu-liu Sun (15205327)

“…In clinical isolates, tolerance to echinocandins in Candida species is mostly due to point mutations of FKS genes, which encode the target protein of echinocandins. However, here, we found chromosome 5 trisomy was the major mechanism of adaptation to the echinocandin drug caspofungin, and FKS mutations were rare events. …”

Image_2_Aneuploidy enables cross-tolerance to unrelated antifungal drugs in Candida parapsilosis.TIF by Liu-liu Sun (15205327)

“…In clinical isolates, tolerance to echinocandins in Candida species is mostly due to point mutations of FKS genes, which encode the target protein of echinocandins. However, here, we found chromosome 5 trisomy was the major mechanism of adaptation to the echinocandin drug caspofungin, and FKS mutations were rare events. …”