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5681
Investigate Pathogenic Mechanism of TXNDC5 in Rheumatoid Arthritis
Published 2013“…We previously detected increased TXNDC5 expression in synovial tissues and blood from RA patients and demonstrated that the gene encoding TXNDC5 increased RA risk. …”
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5682
Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer
Published 2024“…Upon additional modifications of corallorazine D, a candidate compound <b>5k</b>, demonstrated remarkable inhibitory potency against HDAC8 (IC<sub>50</sub> = 0.12 ± 0.01 nM), 89-fold superior to PCI-34051. …”
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5683
Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer
Published 2024“…Upon additional modifications of corallorazine D, a candidate compound <b>5k</b>, demonstrated remarkable inhibitory potency against HDAC8 (IC<sub>50</sub> = 0.12 ± 0.01 nM), 89-fold superior to PCI-34051. …”
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5684
Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer
Published 2024“…Upon additional modifications of corallorazine D, a candidate compound <b>5k</b>, demonstrated remarkable inhibitory potency against HDAC8 (IC<sub>50</sub> = 0.12 ± 0.01 nM), 89-fold superior to PCI-34051. …”
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5685
Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer
Published 2024“…Upon additional modifications of corallorazine D, a candidate compound <b>5k</b>, demonstrated remarkable inhibitory potency against HDAC8 (IC<sub>50</sub> = 0.12 ± 0.01 nM), 89-fold superior to PCI-34051. …”
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5686
Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer
Published 2024“…Upon additional modifications of corallorazine D, a candidate compound <b>5k</b>, demonstrated remarkable inhibitory potency against HDAC8 (IC<sub>50</sub> = 0.12 ± 0.01 nM), 89-fold superior to PCI-34051. …”
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5687
Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer
Published 2024“…Upon additional modifications of corallorazine D, a candidate compound <b>5k</b>, demonstrated remarkable inhibitory potency against HDAC8 (IC<sub>50</sub> = 0.12 ± 0.01 nM), 89-fold superior to PCI-34051. …”
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5688
Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer
Published 2024“…Upon additional modifications of corallorazine D, a candidate compound <b>5k</b>, demonstrated remarkable inhibitory potency against HDAC8 (IC<sub>50</sub> = 0.12 ± 0.01 nM), 89-fold superior to PCI-34051. …”
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5689
Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer
Published 2024“…Upon additional modifications of corallorazine D, a candidate compound <b>5k</b>, demonstrated remarkable inhibitory potency against HDAC8 (IC<sub>50</sub> = 0.12 ± 0.01 nM), 89-fold superior to PCI-34051. …”
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5690
Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer
Published 2024“…Upon additional modifications of corallorazine D, a candidate compound <b>5k</b>, demonstrated remarkable inhibitory potency against HDAC8 (IC<sub>50</sub> = 0.12 ± 0.01 nM), 89-fold superior to PCI-34051. …”
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5691
Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer
Published 2024“…Upon additional modifications of corallorazine D, a candidate compound <b>5k</b>, demonstrated remarkable inhibitory potency against HDAC8 (IC<sub>50</sub> = 0.12 ± 0.01 nM), 89-fold superior to PCI-34051. …”
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5692
Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer
Published 2024“…Upon additional modifications of corallorazine D, a candidate compound <b>5k</b>, demonstrated remarkable inhibitory potency against HDAC8 (IC<sub>50</sub> = 0.12 ± 0.01 nM), 89-fold superior to PCI-34051. …”
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5693
Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer
Published 2024“…Upon additional modifications of corallorazine D, a candidate compound <b>5k</b>, demonstrated remarkable inhibitory potency against HDAC8 (IC<sub>50</sub> = 0.12 ± 0.01 nM), 89-fold superior to PCI-34051. …”
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5694
Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer
Published 2024“…Upon additional modifications of corallorazine D, a candidate compound <b>5k</b>, demonstrated remarkable inhibitory potency against HDAC8 (IC<sub>50</sub> = 0.12 ± 0.01 nM), 89-fold superior to PCI-34051. …”
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5695
Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer
Published 2024“…Upon additional modifications of corallorazine D, a candidate compound <b>5k</b>, demonstrated remarkable inhibitory potency against HDAC8 (IC<sub>50</sub> = 0.12 ± 0.01 nM), 89-fold superior to PCI-34051. …”
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5696
Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer
Published 2024“…Upon additional modifications of corallorazine D, a candidate compound <b>5k</b>, demonstrated remarkable inhibitory potency against HDAC8 (IC<sub>50</sub> = 0.12 ± 0.01 nM), 89-fold superior to PCI-34051. …”
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5697
Image 5_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.tif
Published 2025“…The use of plant growth-promoting bacteria (PGPB) offers a promising alternative to enhance soil quality and crop yield while reducing the consumption of chemical fertilizers.</p>Methods<p>Here, we characterize the plant growth-promoting potential of Azotobacter chroococcum W5 through comparative genomics, in vitro experiments, and metabolomic analyses.…”
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5698
Table 5_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.docx
Published 2025“…The use of plant growth-promoting bacteria (PGPB) offers a promising alternative to enhance soil quality and crop yield while reducing the consumption of chemical fertilizers.</p>Methods<p>Here, we characterize the plant growth-promoting potential of Azotobacter chroococcum W5 through comparative genomics, in vitro experiments, and metabolomic analyses.…”
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5699
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5700
20E repressed ILP-mediated cell membrane translocation of HaP60 and HaP110, dephosphorylated HaP60 and HaP110, and decreased their interaction.
Published 2021“…Green, HaP60 or HaP110; red, cell membrane stained with WGA; blue, nuclei stained with DAPI; merge, overlapped green, blue, and red fluorescence. Bar, 50 μm. <b>C.</b> Co-IP assay showed that 20E decreased the HaP60–HaP110 interaction and induced dephosphorylation in cells. …”