Integrated model of DNA damage repair by non-homologous end joining and p53/p21 mediated early senescence signalling. by David W. P. Dolan (746563)

“…After the cells reaches an early senescent state (Sen) the abundance of Parp-1 and Ku70/80 slowly decreases (**) (see <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1004246#pcbi.1004246.s009" target="_blank">S2 Table</a> for details). …”

Hyperpolarization increases, whereas ZD7288 reduces, both PEMH amplitude in and excitability of Ah-type VGNs. by Guo-Fen Qiao (444187)

“…The peak amplitude of the evoked action potentials progressively decreased to a new steady state value at the end of the pulse train. …”

Supplemental Material for Liu, Ruediger, and Shapira, 2018 by Limeng Liu (5812814)

“…</b>Development (3 days at 20°C) of transgenic worms expressing KGB-1 in neurons (A) or in the intestine (B) raised on NGM plates containing 50 μM cadmium. …”

Ambulatory modeling of vocal hyperfunction (Parra et al., 2025) by Jesús A. Parra (20677929)

Cellular and Molecular Mechanisms Underlie the Anti-Tumor Activities Exerted by <em>Walterinnesia aegyptia</em> Venom Combined with Silica Nanoparticles against Multiple Myeloma Ca... by Gamal Badr (113166)

“…We found that WEV and WEV+NP clearly decreased the CXCL12/CXCR4-mediated activation of AKT, ERK, NFκB and Rho-A using western blot analysis; abrogated the CXCL12-mediated proliferation of MM cells using the CFSE assay; and induced apoptosis in MM cell as determined by PI/annexin V double staining followed by flow cytometry analysis. …”

Data_Sheet_1_Contrasting effects of organic materials versus their derived biochars on maize growth, soil properties and bacterial community in two type soils.docx by Xiaosong Yue (15890882)

“…Our results revealed that straw decreased the shoot biomass of maize in both soils, while straw-derived biochar, manure and manure-derived biochar increased it by 51.50, 35.47 and 74.95% in fluvo-aquic soil and by 36.38, 117.57 and 67.05% in red soil compared with the control, respectively. …”

Epidemiological consequences of repertoire population structure under high <i>var</i> gene diversity. by Shai Pilosof (150055)

“…Each point is the average duration of infection across 50 runs of the ABM for 10 hosts with 5 random starting layers in 10 different modules (see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000336#sec007" target="_blank">Methods</a> and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000336#pbio.3000336.s001" target="_blank">S1 Text</a> for details on experimental design). …”

Expression of an activated ErbB2 molecule mimics <i>Nf2</i> loss in SC NPCs. by Cynthia Garcia (562261)

“…<p>(<b>A</b>) Constitutively-activated ErbB2 (V659E) expression increases SC NPC neurosphere diameters (1.4-fold) (p = 0.0021; two-tailed Mann-Whitney U-test), (<b>B</b>) decreases NPC apoptosis (% cleaved caspase-3⁺ cells; 2.6-fold) (p<0.0001; two-tailed Mann-Whitney U-test), and (<b>C</b>) increases glial differentiation (2.6-fold) (p = 0.0006; two-tailed Mann-Whitney U-test). …”

DataSheet1_Reduction of Matrix Metallopeptidase 13 and Promotion of Chondrogenesis by Zeel T in Primary Human Osteoarthritic Chondrocytes.zip by Christelle Sanchez (709914)

“…The cultures were treated with 20% or 10% (v/v) Ze14 or placebo. For RNA-seq, reads were generated with Illumina NextSeq5000 sequencer and aligned to the human reference genome (UCSC hg19). …”

Cell division characteristics of potential suppressor mutants. by Ilkay Celik Gulsoy (20624015)

Inference under various sources of process variability. by Susanne Pinto (13767952)

“…(C) Decreased and increased amount of measurement noise (<i>υ</i>) and the effect of process noise (<i>W</i>) (<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1010491#pcbi.1010491.s003" target="_blank">S2 Fig</a>). …”

Biochemical and structural impact of two novel missense mutations in cystathionine β-synthase gene associated with homocystinuria by Al-Sadeq, Duaa W.

“…Homocystinuria is a rare disease caused by mutations in the CBS gene that results in a deficiency of cystathionine β-synthase (CBS). …”
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Negative frequency-dependence maintaining coexistence between BCs and ICs. by Albertas Janulevicius (732672)

“…Error bars indicate confidence intervals (<i>α</i> = 0.05) of the mean of the reproduction rates across simulation replicas. …”

How to Perform a Hybrid Endocardial / Epicardial Mapping and Ablation for IST/POTS by Mark La Meir (6864065)

“…<p>Inappropriate sinus tachycardia (IST) is defined as a sinus HR >100 bpm at rest (with a mean 24-hour HR > 90 bpm not due to primary causes) and is associated with distressing symptoms of palpitations, fatigue and exercise intolerance. …”

Paired Immunoglobulin-like Type 2 Receptor Alpha G78R variant alters ligand binding and confers protection to Alzheimer's disease by Nisha Rathore (5924609)

“…The G78R variant alters the interaction of residues essential for sialic acid engagement, resulting in >50% reduced binding for several PILRA ligands including a novel ligand, complement component 4A, and herpes simplex virus 1 (HSV-1) glycoprotein B. …”

Optogenetic closed-loop experiments with MARGO. by Zach Werkhoven (6473165)

“…Even at the lowest intensity (50%), flies show a robust avoidance of the reinforced arm in a Y-Maze. …”

GBE modulated mitochondrial flux control ratios and rose ATP synthesis. by Virginie Rhein (243241)

“…(<b>A–C</b>) Values represent the means ± S.E., GBE treatment effect, paired student's t-test, number of pairs n = 5: #, p<0.05, ##, p<0.01 GBE treated versus corresponding untreated cells; and effect of Aβ, unpaired student's t-test, n = 5, *, p<0.05; ***, p<0.001 APP versus control cells.…”

Image_2_Antidiabetic, Antihyperlipidemic, Antioxidant, Anti-inflammatory Activities of Ethanolic Seed Extract of Annona reticulata L. in Streptozotocin Induced Diabetic Rats.JPEG by Wenbin Wen (7528595)

“…Furthermore, A. reticulata significantly decreased the levels of triglycerides, cholesterol, LDL, and significantly increased the HDL in diabetic rats. …”

Image_3_Antidiabetic, Antihyperlipidemic, Antioxidant, Anti-inflammatory Activities of Ethanolic Seed Extract of Annona reticulata L. in Streptozotocin Induced Diabetic Rats.JPEG by Wenbin Wen (7528595)

“…Furthermore, A. reticulata significantly decreased the levels of triglycerides, cholesterol, LDL, and significantly increased the HDL in diabetic rats. …”

Image_4_Antidiabetic, Antihyperlipidemic, Antioxidant, Anti-inflammatory Activities of Ethanolic Seed Extract of Annona reticulata L. in Streptozotocin Induced Diabetic Rats.JPEG by Wenbin Wen (7528595)

“…Furthermore, A. reticulata significantly decreased the levels of triglycerides, cholesterol, LDL, and significantly increased the HDL in diabetic rats. …”