Search alternatives:
nn decrease » _ decrease (Expand Search), gy decreased (Expand Search), b1 decreased (Expand Search)
wt decrease » we decrease (Expand Search), _ decrease (Expand Search), awd decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
nn decrease » _ decrease (Expand Search), gy decreased (Expand Search), b1 decreased (Expand Search)
wt decrease » we decrease (Expand Search), _ decrease (Expand Search), awd decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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10701
Deletion of <i>Aqp9</i> protects against MPP<sup>+</sup> toxicity <i>in vivo</i>.
Published 2018“…<p>A) Representative midbrain sections of WT and <i>Aqp9</i><sup>-/-</sup> mice, seven days after treatment with unilateral striatal injection of 7.5 μg MPP<sup>+</sup>. …”
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10702
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10703
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10704
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10705
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10706
Small heterodimer partner (SHP) deficiency protects myocardia from lipid accumulation in high fat diet-fed mice
Published 2017“…Transcriptional profiling with a microarray revealed that genes participating in cell growth, cytokine signalling, phospholipid metabolism, and extracellular matrix are up-regulated in the myocardia of SHP knockout (KO) mice compared to those of wild-type (WT) mice (nominal p value < 0.05). Consistent with these gene expression changes, the left ventricular masses of SHP KO mice were significantly higher than WT mice (76.8 ± 20.5 mg vs. 52.8 ± 6.8 mg, P = 0.0093). …”
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10707
Rescue of <i>MBNL</i>1 e5 and <i>MBNL</i>2 e5 and e8 mis-splicing by erythromycin lactobionate treatment at 10 DPI.
Published 2022“…Note the decreased inclusion of <i>MBNL</i>1 e5 (+e5) and <i>MBNL</i>2 e5 (+e5) in DM1 hiNeurons treated with 35 or 65 μM erythromycin for 48 h relative to placebo treated cells. …”
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10708
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10709
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10710
Knock-out of <i>atp6v1e1b</i> in zebrafish shows an early phenotypic read-out.
Published 2021“…Data are expressed as mean ± SD from 5 biological replicates. (C) Band intensities of fluorescence signals of atp6v1e1 and α-tubulin were quantified and normalized to the corresponding WT controls. …”
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10711
Shooting an Arrow against Convulsion: Novel Triazole-Grafted Benzenesulfonamide Derivatives as Carbonic Anhydrase II and VII Inhibitors
Published 2025“…Evaluations of toxicity showed no neurotoxic effects and a high safety margin (LD<sub>50</sub> > 2000 mg/kg). …”
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10712
Shooting an Arrow against Convulsion: Novel Triazole-Grafted Benzenesulfonamide Derivatives as Carbonic Anhydrase II and VII Inhibitors
Published 2025“…Evaluations of toxicity showed no neurotoxic effects and a high safety margin (LD<sub>50</sub> > 2000 mg/kg). …”
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10713
Shooting an Arrow against Convulsion: Novel Triazole-Grafted Benzenesulfonamide Derivatives as Carbonic Anhydrase II and VII Inhibitors
Published 2025“…Evaluations of toxicity showed no neurotoxic effects and a high safety margin (LD<sub>50</sub> > 2000 mg/kg). …”
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10714
Shooting an Arrow against Convulsion: Novel Triazole-Grafted Benzenesulfonamide Derivatives as Carbonic Anhydrase II and VII Inhibitors
Published 2025“…Evaluations of toxicity showed no neurotoxic effects and a high safety margin (LD<sub>50</sub> > 2000 mg/kg). …”
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10715
Shooting an Arrow against Convulsion: Novel Triazole-Grafted Benzenesulfonamide Derivatives as Carbonic Anhydrase II and VII Inhibitors
Published 2025“…Evaluations of toxicity showed no neurotoxic effects and a high safety margin (LD<sub>50</sub> > 2000 mg/kg). …”
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10716
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10717
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10718
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10719
Quantitative structure–toxicity relationship models for predication of toxicity of ionic liquids toward leukemia rat cell line IPC-81 based on index of ideality of correlation
Published 2021“…The outliers and promoters of increase/decrease of logEC<sub>50</sub> are extracted and the mechanistic interpretation of effective descriptors for the model is also offered.Highlights</p><p>Global SMILES-based QSAR model was developed to predict the toxicity of ILs.…”
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10720
DataSheet1_CYP2A6 and GABRA2 Gene Polymorphisms are Associated With Dexmedetomidine Drug Response.docx
Published 2022“…In particular, individuals with the GG genotype had a 4-fold higher risk of heart rate abnormality than carriers of the T allele (OR = 4.32, 95% CI: 1.96–9.50, p = 0.00027).…”