Showing 10,701 - 10,720 results of 46,952 for search '(( 50 ((nn decrease) OR (a decrease)) ) OR ( 5 ((wt decrease) OR (mean decrease)) ))', query time: 1.38s Refine Results
  1. 10701

    Deletion of <i>Aqp9</i> protects against MPP<sup>+</sup> toxicity <i>in vivo</i>. by Katja Stahl (4994483)

    Published 2018
    “…<p>A) Representative midbrain sections of WT and <i>Aqp9</i><sup>-/-</sup> mice, seven days after treatment with unilateral striatal injection of 7.5 μg MPP<sup>+</sup>. …”
  2. 10702
  3. 10703
  4. 10704
  5. 10705
  6. 10706

    Small heterodimer partner (SHP) deficiency protects myocardia from lipid accumulation in high fat diet-fed mice by Jung Hun Ohn (10089)

    Published 2017
    “…Transcriptional profiling with a microarray revealed that genes participating in cell growth, cytokine signalling, phospholipid metabolism, and extracellular matrix are up-regulated in the myocardia of SHP knockout (KO) mice compared to those of wild-type (WT) mice (nominal p value < 0.05). Consistent with these gene expression changes, the left ventricular masses of SHP KO mice were significantly higher than WT mice (76.8 ± 20.5 mg vs. 52.8 ± 6.8 mg, P = 0.0093). …”
  7. 10707

    Rescue of <i>MBNL</i>1 e5 and <i>MBNL</i>2 e5 and e8 mis-splicing by erythromycin lactobionate treatment at 10 DPI. by Mougina K. Eltahir (12988153)

    Published 2022
    “…Note the decreased inclusion of <i>MBNL</i>1 e5 (+e5) and <i>MBNL</i>2 e5 (+e5) in DM1 hiNeurons treated with 35 or 65 μM erythromycin for 48 h relative to placebo treated cells. …”
  8. 10708
  9. 10709
  10. 10710

    Knock-out of <i>atp6v1e1b</i> in zebrafish shows an early phenotypic read-out. by Lore Pottie (10994479)

    Published 2021
    “…Data are expressed as mean ± SD from 5 biological replicates. (C) Band intensities of fluorescence signals of atp6v1e1 and α-tubulin were quantified and normalized to the corresponding WT controls. …”
  11. 10711

    Shooting an Arrow against Convulsion: Novel Triazole-Grafted Benzenesulfonamide Derivatives as Carbonic Anhydrase II and VII Inhibitors by Mohamed A. Zeidan (21099628)

    Published 2025
    “…Evaluations of toxicity showed no neurotoxic effects and a high safety margin (LD<sub>50</sub> > 2000 mg/kg). …”
  12. 10712

    Shooting an Arrow against Convulsion: Novel Triazole-Grafted Benzenesulfonamide Derivatives as Carbonic Anhydrase II and VII Inhibitors by Mohamed A. Zeidan (21099628)

    Published 2025
    “…Evaluations of toxicity showed no neurotoxic effects and a high safety margin (LD<sub>50</sub> > 2000 mg/kg). …”
  13. 10713

    Shooting an Arrow against Convulsion: Novel Triazole-Grafted Benzenesulfonamide Derivatives as Carbonic Anhydrase II and VII Inhibitors by Mohamed A. Zeidan (21099628)

    Published 2025
    “…Evaluations of toxicity showed no neurotoxic effects and a high safety margin (LD<sub>50</sub> > 2000 mg/kg). …”
  14. 10714

    Shooting an Arrow against Convulsion: Novel Triazole-Grafted Benzenesulfonamide Derivatives as Carbonic Anhydrase II and VII Inhibitors by Mohamed A. Zeidan (21099628)

    Published 2025
    “…Evaluations of toxicity showed no neurotoxic effects and a high safety margin (LD<sub>50</sub> > 2000 mg/kg). …”
  15. 10715

    Shooting an Arrow against Convulsion: Novel Triazole-Grafted Benzenesulfonamide Derivatives as Carbonic Anhydrase II and VII Inhibitors by Mohamed A. Zeidan (21099628)

    Published 2025
    “…Evaluations of toxicity showed no neurotoxic effects and a high safety margin (LD<sub>50</sub> > 2000 mg/kg). …”
  16. 10716
  17. 10717
  18. 10718
  19. 10719

    Quantitative structure–toxicity relationship models for predication of toxicity of ionic liquids toward leukemia rat cell line IPC-81 based on index of ideality of correlation by Shahin Ahmadi (9334861)

    Published 2021
    “…The outliers and promoters of increase/decrease of logEC<sub>50</sub> are extracted and the mechanistic interpretation of effective descriptors for the model is also offered.Highlights</p><p>Global SMILES-based QSAR model was developed to predict the toxicity of ILs.…”
  20. 10720

    DataSheet1_CYP2A6 and GABRA2 Gene Polymorphisms are Associated With Dexmedetomidine Drug Response.docx by Chao Fang (456315)

    Published 2022
    “…In particular, individuals with the GG genotype had a 4-fold higher risk of heart rate abnormality than carriers of the T allele (OR = 4.32, 95% CI: 1.96–9.50, p = 0.00027).…”