Showing 11,241 - 11,260 results of 46,952 for search '(( 50 ((nn decrease) OR (a decrease)) ) OR ( 5 ((wt decrease) OR (mean decrease)) ))', query time: 1.33s Refine Results
  1. 11241
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  3. 11243

    Supplementary Table 1 - Additional PSD Results by David Aguilar (7148330)

    Published 2019
    “…</b>Arrows represent a significant increase (↑) or decrease (↓) in normalized mGluR5 KO spectral power compared to WT controls in the same condition. …”
  4. 11244

    GFP-LL5β(381–510) inhibits tumor cell invasion. by Lucrezia Maria Ribolla (16535119)

    Published 2023
    “…(<b>D</b>) Clones of MDA-MB-231 cells expressing the indicated GFP-tagged proteins were used for transwell Matrigel invasion assays: invasion is significantly decreased for cells expressing GFP-LL5β(381–510), but not for cells expressing either GFP or GFP-LL5β(305–450). …”
  5. 11245
  6. 11246
  7. 11247

    Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery by Pasquale Linciano (4426435)

    Published 2017
    “…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC<sub>50</sub> = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC<sub>50</sub> value. …”
  8. 11248

    Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery by Pasquale Linciano (4426435)

    Published 2017
    “…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC<sub>50</sub> = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC<sub>50</sub> value. …”
  9. 11249

    Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery by Pasquale Linciano (4426435)

    Published 2017
    “…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC<sub>50</sub> = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC<sub>50</sub> value. …”
  10. 11250

    Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery by Pasquale Linciano (4426435)

    Published 2017
    “…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC<sub>50</sub> = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC<sub>50</sub> value. …”
  11. 11251

    Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery by Pasquale Linciano (4426435)

    Published 2017
    “…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC<sub>50</sub> = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC<sub>50</sub> value. …”
  12. 11252

    Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery by Pasquale Linciano (4426435)

    Published 2017
    “…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC<sub>50</sub> = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC<sub>50</sub> value. …”
  13. 11253

    Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery by Pasquale Linciano (4426435)

    Published 2017
    “…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC<sub>50</sub> = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC<sub>50</sub> value. …”
  14. 11254

    Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery by Pasquale Linciano (4426435)

    Published 2017
    “…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC<sub>50</sub> = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC<sub>50</sub> value. …”
  15. 11255
  16. 11256

    Structure-function correlation of the central retina in a patient with X-linked retinoschisis (upper panels) and a patient with Usher syndrome 2A (lower panels). by Peter Charbel Issa (241475)

    Published 2010
    “…Only the most distinct alterations result in a relative scotoma (10 dB decreased light intensity compared to the brightest stimulus). …”
  17. 11257

    JMJD5 forms a complex with CRY1–FBXL3 and leads to CRY1 degradation. by Anand R. Saran (6034127)

    Published 2018
    “…(D) Knockdown of FBXL3 decreases JMJD5 co-IP with CRY1. Densitometric analysis showing ratio of JMJD5 to CRY1 signals from these experiments (mean ± SEM, <i>n</i> = 4) are shown in (E). …”
  18. 11258

    5-Choice Serial Reaction Time Task (5-CSRTT) Results Longitudinally for <i>Hdh</i><sup><i>Q111/+</i></sup> animals over 18 months of testing. by Emma Yhnell (3193398)

    Published 2016
    “…Data are shown for a total of 16 mice, 7 <i>Hdh</i><sup><i>Q111/+</i></sup> and 9 wild type and is the average number of responses made over 5 days of testing at each stimulus length. Error bars represent ± standard error of the mean. * p<0.05, ** p<0.01, *** p<0.001.…”
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