Search alternatives:
nn decrease » _ decrease (Expand Search), gy decreased (Expand Search), b1 decreased (Expand Search)
wt decrease » we decrease (Expand Search), _ decrease (Expand Search), awd decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
nn decrease » _ decrease (Expand Search), gy decreased (Expand Search), b1 decreased (Expand Search)
wt decrease » we decrease (Expand Search), _ decrease (Expand Search), awd decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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11241
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11242
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11243
Supplementary Table 1 - Additional PSD Results
Published 2019“…</b>Arrows represent a significant increase (↑) or decrease (↓) in normalized mGluR5 KO spectral power compared to WT controls in the same condition. …”
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11244
GFP-LL5β(381–510) inhibits tumor cell invasion.
Published 2023“…(<b>D</b>) Clones of MDA-MB-231 cells expressing the indicated GFP-tagged proteins were used for transwell Matrigel invasion assays: invasion is significantly decreased for cells expressing GFP-LL5β(381–510), but not for cells expressing either GFP or GFP-LL5β(305–450). …”
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11245
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11246
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11247
Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery
Published 2017“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC<sub>50</sub> = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC<sub>50</sub> value. …”
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11248
Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery
Published 2017“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC<sub>50</sub> = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC<sub>50</sub> value. …”
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11249
Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery
Published 2017“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC<sub>50</sub> = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC<sub>50</sub> value. …”
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11250
Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery
Published 2017“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC<sub>50</sub> = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC<sub>50</sub> value. …”
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11251
Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery
Published 2017“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC<sub>50</sub> = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC<sub>50</sub> value. …”
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11252
Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery
Published 2017“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC<sub>50</sub> = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC<sub>50</sub> value. …”
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11253
Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery
Published 2017“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC<sub>50</sub> = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC<sub>50</sub> value. …”
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11254
Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery
Published 2017“…In particular, compound <b>4m</b>, a biphenyl-thiadiazole-2,5-diamine with IC<sub>50</sub> = 16 μM, was able to potentiate the antitrypanosomal activity of the dihydrofolate reductase inhibitor methotrexate (MTX) with a 4.1-fold decrease of the EC<sub>50</sub> value. …”
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11255
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11256
Structure-function correlation of the central retina in a patient with X-linked retinoschisis (upper panels) and a patient with Usher syndrome 2A (lower panels).
Published 2010“…Only the most distinct alterations result in a relative scotoma (10 dB decreased light intensity compared to the brightest stimulus). …”
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11257
JMJD5 forms a complex with CRY1–FBXL3 and leads to CRY1 degradation.
Published 2018“…(D) Knockdown of FBXL3 decreases JMJD5 co-IP with CRY1. Densitometric analysis showing ratio of JMJD5 to CRY1 signals from these experiments (mean ± SEM, <i>n</i> = 4) are shown in (E). …”
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11258
5-Choice Serial Reaction Time Task (5-CSRTT) Results Longitudinally for <i>Hdh</i><sup><i>Q111/+</i></sup> animals over 18 months of testing.
Published 2016“…Data are shown for a total of 16 mice, 7 <i>Hdh</i><sup><i>Q111/+</i></sup> and 9 wild type and is the average number of responses made over 5 days of testing at each stimulus length. Error bars represent ± standard error of the mean. * p<0.05, ** p<0.01, *** p<0.001.…”
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11259
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11260