Effect of <i>CYP6d5</i> knockdown in Drosophila caffeine metabolism. by Alexandra Coelho (691773)

“…<p>A- The comparison of the normalized quantities of caffeine metabolites reveals a dramatic decrease of theobromine combined with a substantial increase of M2 in <i>CYP6d5</i> silenced flies (ds<i>CYP6d5</i>/<i>Actin</i>-GAL4) compared to the two transgenic parental controls (<i>Actin</i>-GAL4/+, ds<i>CYP6d5</i>/+). …”

S1 Data - by Angélica González Maciel (18946369)

The classification proportions across cross-sectional age over five select cognitive systems: a) auditory-left (Aud-L; dark blue), b) auditory-right (Aud-R; dark purple), c) ventra... by Andrew Patton (10224161)

S1 Data - by Elizabeth Dufourcq Sekatcheff (17457627)

“…Thus, sperm decrease seems to be mediated via another mechanism, probably a decrease in germ cell proliferation speed that needs further investigation to better characterize sex-specific responses to IR exposure. …”

Trip characteristics comparing < 5-month-old pups (this study) to all other age classes [26, 37] including trip duration (d), surface speed (km h^-1), distance to shore (... by Benia V. R. Nowak (17054285)

Baseline Transmission (None) and Five Intervention Scenarios: Q, QI, QA, QIA, and QIAC by Joseph T Wu (31525)

“…Therefore, the rate of transmission decreased by 75% within a peer group when one of two infected individuals complied with quarantine and by 96% if both did. …”

Maternal consumption of green tea extract during pregnancy and lactation alters offspring's metabolism in rats - Fig 2 by Ana C. L. Hachul (5533091)

Descriptive statistics for pulse pressure , the pulsatility index , and the damping factors obtained from these two indexes ( and ) in the pial vascular networks for the different... by Eduardo G. Zilves (22209247)

Tissues cytokine content. by Ana C. L. Hachul (5533091)

Injection of human mesenchymal stem/stromal cells (hMSCs) suppresses spinal cord injury (SCI) symptoms. by Kazumichi Yagura (4537504)

“…<i>Eno2</i> expression was temporarily decreased on pod 3 in the HBSS-treated group (n = 5 mouse). …”

Jatrophane Diterpenoids from <i>Euphorbia glomerulans</i> by Aobulikasimu Hasan (6448166)

“…Several compounds showed different chemoreversal activities and considerably decreased cytotoxicity. Compounds <b>11</b> (IC₅₀ value of 5.0 ± 0.8 μM) and <b>12</b> (IC₅₀ value of 5.2 ± 2.0 μM) possessed MDR reversal activities that were as good as that of verapamil (IC₅₀ value of 4.7 ± 0.6 μM).…”

Jatrophane Diterpenoids from <i>Euphorbia glomerulans</i> by Aobulikasimu Hasan (6448166)

“…Several compounds showed different chemoreversal activities and considerably decreased cytotoxicity. Compounds <b>11</b> (IC₅₀ value of 5.0 ± 0.8 μM) and <b>12</b> (IC₅₀ value of 5.2 ± 2.0 μM) possessed MDR reversal activities that were as good as that of verapamil (IC₅₀ value of 4.7 ± 0.6 μM).…”

Jatrophane Diterpenoids from <i>Euphorbia glomerulans</i> by Aobulikasimu Hasan (6448166)

“…Several compounds showed different chemoreversal activities and considerably decreased cytotoxicity. Compounds <b>11</b> (IC₅₀ value of 5.0 ± 0.8 μM) and <b>12</b> (IC₅₀ value of 5.2 ± 2.0 μM) possessed MDR reversal activities that were as good as that of verapamil (IC₅₀ value of 4.7 ± 0.6 μM).…”

Image_5_Heterogeneity in the isolation of patches may be essential for the action of metacommunity mechanisms.JPEG by Ana I. Borthagaray (14952037)

Effect of elastase injection on <i>Fbln5</i> Cre+cKO mice. by Kathleen Chin (275937)

“…F5^-/-, negative control; Ctl, nonpregnant wild type; PP, 48 h postpartum wild type control indicating decrease in Fbln5. …”

Four-Dimensional Characterization of Thrombosis in a Live-Cell, Shear-Flow Assay: Development and Application to Xenotransplantation by Donald G. Harris (715907)

“…To mimic microcirculatory flow, channels were perfused at 5 dynes/cm² and 37°C with human blood stained to fluorescently label platelets. …”

Extended exposure to extracellular adenosine (ADO) causes a dose-dependent reduction in chlamydial development via the A2b adenosine receptor. by Matthew A. Pettengill (256020)

“…(<b>B</b>) HeLa cell knock-downs (KDs) were produced with non-targeted (Control), A2a-targeted (A2a KD) or A2b-targeted (A2b KD) shRNA and levels of target KD verified to be decreased at least 50% by qPCR. …”

Assessment of indicators of vitamin A status in non-cirrhotic chronic hepatitis C patients by R.C. Santana (6516497)

Activated CD4+ CD45RO+ memory T-cells decrease secretion of soluble caspase-1 and P2X7R mRNA expression in monocytes leading to a reduced response upon ATP binding. by Vanessa Beynon (153924)

“…<p>a) sCaspase-1 levels in the supernatant of monocytes was measured by ELISA (n = 8). A significant decrease of soluble Caspase-1 in the supernatant of cells co-cultured with activated memory T-cells was observed both in the presence and absence of IFNβ; b) intracellular levels of pro-IL-1β measured with an ELISA specific for the immature precursor of IL-1β showed a significant increase in pro-IL-1β levels in the presence of human activated CD4+CD45RO+ memory T-cells (n = 3), cell lysates from adherent monocytes were obtained after removal of non-adherent T-cells after addition of LPS and prior to incubation with ATP c) the ratio of intracellular pro-IL-1β to released soluble Caspase-1 is significantly increased in the presence of human activated CD4+CD45RO+ memory T-cells (n = 3). d) <i>P2X7R</i> mRNA expression in monocytes cultured overnight with activated CD4+CD45RO+ memory T-cells is decreased with and without addition of exogenous IFNβ (n = 3), mRNA was isolated from adherent monocytes after removal of non-adherent T-cells after addition of LPS and prior to incubation with ATP (Data are shown as means ± SD of duplicate cultures; *p<0.05; **p<0.01 employing repeated measures ANOVA with post-hoc Bonferroni adjustment for multiple comparisons to avoid random correlations); e) Ca²⁺-influx measurement in monocytes cultured with activated human CD4+CD45RO+ memory T-cells in the presence of IFNβ demonstrates the absence of slow sustained Ca²⁺-influx mediated by ATP binding to the purinergic P2X7-receptor (representative of 3 independent experiments); f) Annexin V staining of monocytes coincubated with T-cells and stimulated with LPS was measured by flow cytometry (representative flow cytometry histogram of n = 5).…”

(S12 Data). by Bianca Pellegrino (20314999)