SILD increases renal expression of TEMs pro-angiogenic macrophages. by Mary Anna Venneri (737094)

K_v4 Modulates Repolarization of the AP and AHP, with No Effect on the Sodium Current. by Yong Ping (233004)

“…Na⁺ currents were recorded in response to voltage jumps to potentials from −40 to +40 mV, in 5 mV increments, from a holding potential of −100 mV. …”

REG-O3 chimeric peptide combining growth hormone and somatostatin sequences improves joint function and prevents cartilage degradation in rat model of traumatic knee osteoarthritis by Rodrick Montjean (400649)

“…The effect of REG-O3, solubilized in a liposomal solution and injected at either 5, 25 or 50 μg/50 μL, was compared to liposomal (LIP), dexamethasone and hyaluronic acid (HA) solutions. …”

Supplementary Figure S1. Vigilance States During and After Sleep Deprivation. by David Aguilar (7148330)

IDN5706 inhibits proteolytic processing of APP to CTFs, and production of Aβ species. by Viviana A. Cavieres (500139)

IDN5706 reduces the levels of EDEM1 in a time-dependent manner. by Viviana A. Cavieres (500139)

PSD95 immunoreactivity. by Carola I. F. Janssen (414818)

“…In the SEN, ApoE^-/- mice showed a slight trend (<i>p</i> = 0.064) for decreased PSD95 expression. Values represent mean±SEM; WT CTRL n = 8, WT HF n = 8, ApoE4 CTRL n = 8, ApoE4 HF n = 7, ApoE^-/- CTRL n = 5, ApoE^-/- HF n = 7. #0.05</p>…”

Efficacy and Acceptability of Glycemic Control of Glucagon-Like Peptide-1 Receptor Agonists among Type 2 Diabetes: A Systematic Review and Network Meta-Analysis by Zhixia Li (2736331)

“…Dulaglutide, exenatide long-acting release (exe_lar), liraglutide and taspoglutide had significant lowering effect when compared with sitagliptin (HbA1c<7.0%) and insulin (HbA1c<6.5%). Finally, according to SUCRAs, placebo, thiazolidinediones and albiglutide had the best decrease effect on hypoglycemia; sulphanylureas, sitagliptin and insulin decrease the incidence of treatment discontinuation most; exe_lar and dulaglutide had the highest impact on glycemic level among 13 treatments.…”

Apoptosis is enhanced in DCE- or CS-treated keratinocytes. by Claudia Scarponi (205759)

Effect of partial Glo-I inhibition by EP on LPS-induced production of TNF-α, collagen-I and α-SMA in HSC. by Marcus Hollenbach (376231)

“…Presence of LPS and treatment with low-level concentrations of MGO (indicating partial inhibition of Glo-I activity without complete enzyme inhibition) showed significant decrease of LPS-induced release of TNF-α (absence vs. presence of 10mM MGO: 371.8±22.7 vs. 60.9±11.2 pg/ml; p<0.001), collagen-I (10.0±0.3 vs. 1.8±0.5 ng/ml; p<0.001) and α-SMA (68.6±3.6 vs. 43.8±2.2 ng/ml; p<0.001) <b>(A2, B2, C2)</b>. …”

Effects of 20 μM 5-aza-dC Treatment on the 10q25 Neocentromere by Nicholas C Wong (14627)

“…Six CpG islets (28, 31, 69, 70, 71, and 101) showed an increase in DNA methylation upon the formation of the 10q25 neocentromere. However, following 5-aza-dC treatment, the methylation level of these CpG islets decreased significantly. …”

Virulence dependent inhibition of glycolysis in <i>S</i>. Typhimurium infected macrophages. by Saray Gutiérrez (11473528)

CD68 immunoreactivity. by Carola I. F. Janssen (414818)

“…In addition, ApoE-/- displayed increased inflammation when compared to WT mice (p = 0.029). Values represent mean±SEM; WT CTRL n = 5, WT HF n = 7, ApoE4 CTRL n = 7, ApoE4 HF n = 5, ApoE-/- CTRL n = 4, ApoE-/- HF n = 6. …”

Expression of LvrAB requires at least one functional PerR homolog but the absence of LvrAB alone is not solely responsible for avirulence of the <i>perRA/B</i> double mutant. by André A. Grassmann (11141592)

LM11A-31's effect on cholinergic dystrophic neurites in cortex of mid-stage APP^L/S mice. by Danielle A. Simmons (621167)

“…Scale bar in photomicrograph A = 50 µm. Quantitative analysis showed that LM11A-31 decreases the total area occupied by the clusters (<b><i>C</i></b>) by decreasing their number (<b><i>D</i></b>) but not the mean area per cluster (<b><i>E</i></b>). …”

Representative data from primary HTS. by Pamela Y. Ting (713174)

Working model for REG-O3 mechanism of action. by Rodrick Montjean (400649)

Arf6 recruits the Rac GEF Kalirin to the plasma membrane facilitating Rac activation-5 by Tae Hyeon Koo (77248)

“…D. Expression of EFA6 decreases the interaction between Arf6 and Kalirin5. …”

Hap2p and Hap5p transcription factors are required for lactate assimilation and virulence. by Keigo Ueno (206625)

“…(B) Lactate assimilation was decreased in Δhap2 and Δhap5 strains. Strains were cultivated on lactate plates (2% agar,pH 5.0) for 3 days at 37°C (Upper panel), and in liquid medium containing 2% L-lactate for 5 days at 37°C. …”

Effects of COS on the expression of MCP-1 and iNOS mRNA in RGC-5 cells. by I-Mo Fang (470460)

“…<p>RGC-5 cells were stimulated with 0.5mM PQ and then treated with 50 μg/ml (low-dose) or 100 μg/ml (high-dose) COS for 12 hours. …”