Interference assay with reconstituted Cascade complexes. by Michael Daume (620033)

“…A decreased cleavage activity can be observed for the Cascade complexes containing the Csa5 mutants. …”

A mechanism of non-target site resistance conferred by loss-of-function of <i>PAM16</i> is conserved in <i>M</i>. <i>polymorpha</i>. by Chloe Casey (14341756)

Effect of native (hOb) and Q90L obestatin (hObQ90L) on the ghrelin-induced (Ghr) decrease of evoked GABA synaptic responses in GHRH neurons. by Rim Hassouna (113060)

Response of the metabosensitive fibers to chemicals. by Guillaume Caron (816032)

“…Responses to LA were significantly decreased for the 1 mM concentration in all BoNT/A groups (B0: §, p<0.05; B50: §, p<0.05 and B100: §§§, p<0.001) compared to the respective concentration of the Control group. …”

Membrane-localized AR facilitates productive endocytosis and nuclear trafficking of KSHV. by Xing Wang (154377)

“…Cells were performed as mentioned above, except lacking of Triton X-100 treatment in non-permeabilized group. Scale bars represent 50 μm. (c) Knockdown of AR and EphA2 expression reduces KSHV endocytosis, as indicated by decreasing gB staining in cells. …”

The photoreceptor phyB negatively regulates PIF4 autoinhibition. by Sreya Das (20531295)

COP1/DET1 module promotes PIF4 autoinhibition. by Sreya Das (20531295)

LCR activity and background Ca at low and high SR Ca pumping rate Pup of 4 mM/s and 24 mM/s as membrane depolarizes from the MDP (Maximal Diastolic Potential) to -50 mV (a threshol... by Alexander V. Maltsev (4229458)

Structure of the V66I:V73I:Y160F PfPNP mutant with transition state inhibitor ImmH. by Teraya M. Donaldson (506944)

“…The highlighted imino nitrogen is in <i>blue</i> and the 5′-hydroxyl oxygen is in <i>red</i>. <b>B</b>) Side by side images of the decreased convalent interactions located in the enzymatic pocket of V66I:V73I:Y160F PfPNP mutant (3FOW) on the right with WT PfPNP (1NW4) as a comparison.…”

A mathematical model of PIF4 autoregulation captures the experimental observations of hypocotyl growth and promoter activity. by Sreya Das (20531295)

<i>Helicobacter hepaticus</i> Infection Promotes Hepatitis and Preneoplastic Foci in Farnesoid X Receptor (FXR) Deficient Mice by Alton G. Swennes (625045)

“…FXR deficiency was also a potent modulator of the cecal microbiota, as observed by a strong decrease in alpha diversity. A significant decrease in Firmicutes, particularly members of the order Clostridiales, was observed in FXR KO mice (<i>P</i><0.05 and FDR<5%, ANOVA). …”

High-dose thiamine prevents brain lesions and prolongs survival of <i>Slc19a3</i>-deficient mice by Kaoru Suzuki (4217638)

“…In contrast, when the diet was changed to a high-thiamine diet (thiamine: 8.50 mg/100 g food) after thiamine restriction, more than half of homozygous KO mice survived, without progression of brain lesions. …”

FAK, but not Pyk2 is required for GPVI-mediated ROS generation and platelet aggregation. A. by Naadiya Carrim (664456)

Heterogeneity of HASM membrane potential responses evoked by procontractile agonists co-treated with TAS2R agonists. by Blanca Camoretti-Mercado (762326)

Investigate Pathogenic Mechanism of TXNDC5 in Rheumatoid Arthritis by Lin Wang (11986)

“…CIA was observed in 80% of the TXNDC5-Tg, but only 20% of the wild-type mice (WT) developed CIA. …”

ACKR2 contributes to pulmonary dysfunction by shaping CCL5:CCR5-dependent recruitment of lymphocytes during Influenza A infection in mice by Luciana Padua Tavares (7541546)

“…<p>Supplementary Figure 3 – Proposed mechanism: ACKR2 decreased pulmonary tolerance to influenza A virus infection by reducing CCL5 levels and impairing the development of cellular and humoral antiviral responses and tissue protection. …”

Urolithin A treatment slows reproductive decline in wild type. by Vanessa Cota (13833956)

PIF4 autoinhibits its expression depending on photoperiods. by Sreya Das (20531295)

UV-irradiated M-phase cells show decreased MCM 2–7 loading and G1 arrest after release: HEK293 cells and U2OS cells. by Masayuki Morino (304956)

miR-200c regulates migration associated genes such as filamin A. by Bojan Ljepoja (4921255)

“…<p>(a) A proteomic analysis of a TALENs knock-out (KO) of miR-200c in MCF7 cells revealed a set of proteins with differential expression, of which 50% are involved in migratory processes and are shown in the table. …”