The GluN2B-C456Y mutation leads to decreases in GluN2B and GluN1 protein levels and GluN2B-containing NMDAR currents in mice. by Wangyong Shin (6793040)

“…Note the faster decay kinetics of the mutant NMDAR currents, indicative of a decrease in the GluN2B component. <i>n</i> = 10 neurons from 5 mice for WT, and 9 (5) for HT, *<i>P</i> < 0.05, **<i>P</i> < 0.01, Student <i>t</i> test. …”

Age-specific survival rate (<i>l</i>_<i>x</i>), fecundity (<i>m</i>_<i>x</i>), and maternity (<i>l</i>_<i>x</i><i>m</i>_<i>x</i>) of <i>A</i... by Aonan Zhang (8933630)

Age-specific survival rate (<i>l</i>_<i>x</i>), fecundity (<i>m</i>_<i>x</i>), and maternity (<i>l</i>_<i>x</i><i>m</i>_<i>x</i>) of <i>A</i... by Aonan Zhang (8933630)

Sensitivity of SbV-resistant <i>L. panamensis</i> parasites to edelfosine. by Rubén E. Varela-M (326741)

“…(C) IC₅₀ values of edelfosine, miltefosine, perifosine, and erucylphosphocholine (ErPC) for <i>in vitro</i> growth inhibition of wild type (wt) and SbV-resistant (SbV-R) <i>L. panamensis</i> (<i>Lp</i>) promastigotes were determined by XTT assays. …”

Figure S1-S21 from miR-196b-5p Regulates Colorectal Cancer Cell Migration and Metastases through Interaction with HOXB7 and GALNT5 by Verena Stiegelbauer (4582930)

“…<p>Supplementary Figure S1 Expression levels of miR-196b-5p in different tumor stages and tumor grade. (A-B) In cohort 1, miR-196b-5p expression decreased with (A) higher tumor stage, whereas no difference could be observed for (B) tumor grade. …”

Effects of increasing temperature and, CO₂ on quality of litter, shredders, and microorganisms in Amazonian aquatic systems by Renato Tavares Martins (4634317)

“…We hypothesized that simulated climate change (warming and elevated CO₂) would: i) decrease leaf-litter quality, ii) decrease survival and leaf breakdown by shredders, and iii) increase microbial leaf breakdown and fungal biomass. …”

cGAS deficiency promoted EV-A71- and FMDV-induced mice death. by Huisheng Liu (408091)

The expression of <i>SATB2</i> (A) and <i>XLOC_036765</i> (B) at the four developmental phases in Landrace and Tongcheng pigs. by Yalan Yang (735975)

Titration results for BMV-1a helix A bound to SDS micelles with 16-DSA. by Ling Liu (143030)

“…a<p>50% signal intensity decrease with the addition of less than 3.2 mM DSA.…”

PSD curves of cells at different densities. by Mingkun Pang (11873753)

Effect of Acidic Polymers on the Morphology of Laser-Induced Nucleation of Cesium Chloride by Yao Liu (173014)

“…With the effect of more than 5 wt % PESA, the resulting crystalline morphology obtained by laser was flower-like crystals, whilst cuboid-shaped crystals could be obtained by spontaneous nucleation. …”

Effect of Acidic Polymers on the Morphology of Laser-Induced Nucleation of Cesium Chloride by Yao Liu (173014)

“…With the effect of more than 5 wt % PESA, the resulting crystalline morphology obtained by laser was flower-like crystals, whilst cuboid-shaped crystals could be obtained by spontaneous nucleation. …”

Image 9_Behavioral and biochemical changes associated with the analgesic effects of (2R,6R)-hydroxynorketamine alone and in combination with meloxicam following disk puncture in mi... by Vaskar Das (21529538)

“…EC₅₀ estimates for (2R,6R)-Hydroxynorketamine were 14.2 mg/kg (95% CI: 10.3 mg/kg to 19.7 mg/kg) in male and 16.9 mg/kg (95% CI: 12.8 mg/kg to 22.3 mg/kg) in female mice (P < 0.637). (2R,6R)-Hydroxynorketamine plus meloxicam enhanced the analgesic effect on the AUC_0−3d of meloxicam alone. (2R,6R)-Hydroxynorketamine analgesia was associated with increases in Glutamate receptor A1 & A2, p-Kv2.1, p-CaMKII and reduced BDNF protein ratios in the hippocampus, attenuated c-Fos in the spinal cord, and decreased BDNF at the dorsal root ganglion (DRG).…”

Image 8_Behavioral and biochemical changes associated with the analgesic effects of (2R,6R)-hydroxynorketamine alone and in combination with meloxicam following disk puncture in mi... by Vaskar Das (21529538)

“…EC₅₀ estimates for (2R,6R)-Hydroxynorketamine were 14.2 mg/kg (95% CI: 10.3 mg/kg to 19.7 mg/kg) in male and 16.9 mg/kg (95% CI: 12.8 mg/kg to 22.3 mg/kg) in female mice (P < 0.637). (2R,6R)-Hydroxynorketamine plus meloxicam enhanced the analgesic effect on the AUC_0−3d of meloxicam alone. (2R,6R)-Hydroxynorketamine analgesia was associated with increases in Glutamate receptor A1 & A2, p-Kv2.1, p-CaMKII and reduced BDNF protein ratios in the hippocampus, attenuated c-Fos in the spinal cord, and decreased BDNF at the dorsal root ganglion (DRG).…”

Image 7_Behavioral and biochemical changes associated with the analgesic effects of (2R,6R)-hydroxynorketamine alone and in combination with meloxicam following disk puncture in mi... by Vaskar Das (21529538)

“…EC₅₀ estimates for (2R,6R)-Hydroxynorketamine were 14.2 mg/kg (95% CI: 10.3 mg/kg to 19.7 mg/kg) in male and 16.9 mg/kg (95% CI: 12.8 mg/kg to 22.3 mg/kg) in female mice (P < 0.637). (2R,6R)-Hydroxynorketamine plus meloxicam enhanced the analgesic effect on the AUC_0−3d of meloxicam alone. (2R,6R)-Hydroxynorketamine analgesia was associated with increases in Glutamate receptor A1 & A2, p-Kv2.1, p-CaMKII and reduced BDNF protein ratios in the hippocampus, attenuated c-Fos in the spinal cord, and decreased BDNF at the dorsal root ganglion (DRG).…”

Data Sheet 11_Behavioral and biochemical changes associated with the analgesic effects of (2R,6R)-hydroxynorketamine alone and in combination with meloxicam following disk puncture... by Vaskar Das (21529538)

“…EC₅₀ estimates for (2R,6R)-Hydroxynorketamine were 14.2 mg/kg (95% CI: 10.3 mg/kg to 19.7 mg/kg) in male and 16.9 mg/kg (95% CI: 12.8 mg/kg to 22.3 mg/kg) in female mice (P < 0.637). (2R,6R)-Hydroxynorketamine plus meloxicam enhanced the analgesic effect on the AUC_0−3d of meloxicam alone. (2R,6R)-Hydroxynorketamine analgesia was associated with increases in Glutamate receptor A1 & A2, p-Kv2.1, p-CaMKII and reduced BDNF protein ratios in the hippocampus, attenuated c-Fos in the spinal cord, and decreased BDNF at the dorsal root ganglion (DRG).…”

Data Sheet 2_Behavioral and biochemical changes associated with the analgesic effects of (2R,6R)-hydroxynorketamine alone and in combination with meloxicam following disk puncture... by Vaskar Das (21529538)

“…EC₅₀ estimates for (2R,6R)-Hydroxynorketamine were 14.2 mg/kg (95% CI: 10.3 mg/kg to 19.7 mg/kg) in male and 16.9 mg/kg (95% CI: 12.8 mg/kg to 22.3 mg/kg) in female mice (P < 0.637). (2R,6R)-Hydroxynorketamine plus meloxicam enhanced the analgesic effect on the AUC_0−3d of meloxicam alone. (2R,6R)-Hydroxynorketamine analgesia was associated with increases in Glutamate receptor A1 & A2, p-Kv2.1, p-CaMKII and reduced BDNF protein ratios in the hippocampus, attenuated c-Fos in the spinal cord, and decreased BDNF at the dorsal root ganglion (DRG).…”

Data Sheet 1_Behavioral and biochemical changes associated with the analgesic effects of (2R,6R)-hydroxynorketamine alone and in combination with meloxicam following disk puncture... by Vaskar Das (21529538)

“…EC₅₀ estimates for (2R,6R)-Hydroxynorketamine were 14.2 mg/kg (95% CI: 10.3 mg/kg to 19.7 mg/kg) in male and 16.9 mg/kg (95% CI: 12.8 mg/kg to 22.3 mg/kg) in female mice (P < 0.637). (2R,6R)-Hydroxynorketamine plus meloxicam enhanced the analgesic effect on the AUC_0−3d of meloxicam alone. (2R,6R)-Hydroxynorketamine analgesia was associated with increases in Glutamate receptor A1 & A2, p-Kv2.1, p-CaMKII and reduced BDNF protein ratios in the hippocampus, attenuated c-Fos in the spinal cord, and decreased BDNF at the dorsal root ganglion (DRG).…”

Data Sheet 3_Behavioral and biochemical changes associated with the analgesic effects of (2R,6R)-hydroxynorketamine alone and in combination with meloxicam following disk puncture... by Vaskar Das (21529538)

“…EC₅₀ estimates for (2R,6R)-Hydroxynorketamine were 14.2 mg/kg (95% CI: 10.3 mg/kg to 19.7 mg/kg) in male and 16.9 mg/kg (95% CI: 12.8 mg/kg to 22.3 mg/kg) in female mice (P < 0.637). (2R,6R)-Hydroxynorketamine plus meloxicam enhanced the analgesic effect on the AUC_0−3d of meloxicam alone. (2R,6R)-Hydroxynorketamine analgesia was associated with increases in Glutamate receptor A1 & A2, p-Kv2.1, p-CaMKII and reduced BDNF protein ratios in the hippocampus, attenuated c-Fos in the spinal cord, and decreased BDNF at the dorsal root ganglion (DRG).…”

Data Sheet 10_Behavioral and biochemical changes associated with the analgesic effects of (2R,6R)-hydroxynorketamine alone and in combination with meloxicam following disk puncture... by Vaskar Das (21529538)

“…EC₅₀ estimates for (2R,6R)-Hydroxynorketamine were 14.2 mg/kg (95% CI: 10.3 mg/kg to 19.7 mg/kg) in male and 16.9 mg/kg (95% CI: 12.8 mg/kg to 22.3 mg/kg) in female mice (P < 0.637). (2R,6R)-Hydroxynorketamine plus meloxicam enhanced the analgesic effect on the AUC_0−3d of meloxicam alone. (2R,6R)-Hydroxynorketamine analgesia was associated with increases in Glutamate receptor A1 & A2, p-Kv2.1, p-CaMKII and reduced BDNF protein ratios in the hippocampus, attenuated c-Fos in the spinal cord, and decreased BDNF at the dorsal root ganglion (DRG).…”