Generation of Circularly Permuted Fluorescent-Protein-Based Indicators for In Vitro and In Vivo Detection of Citrate by Yuki Honda (414507)

“…The novel indicator CF98 can be a specific and simple detection tool for citrate <i>in vitro</i> and a non-invasive tool for real-time estimation of intracellular concentrations of the compound <i>in vivo</i>.…”

Datasheet3_Motor flexibility to stabilize the toe position during obstacle crossing in older adults: an investigation using an uncontrolled manifold analysis.pdf by Yuki Suda (3928037)

“…Introduction<p>An age-related decrease in the ability to exploit the abundant degrees of freedom of the body, referred to as motor flexibility, leads to a heightened fall risk. …”

REST–less breast cancer tumors display high levels of REST4 splicing and poor prognosis. by Matthew P. Wagoner (247464)

“…(C) Patients with REST–less breast tumors in the superseries GSE6532, as defined by the 24-gene signature, show a significant decrease in their disease free survival with respect to their RESTfl counterparts (p<0.01).…”

SmedCB RNAi treatment reduces cathepsin B mRNA levels and proteolytic activity, inhibiting digestion. by Louise S. Goupil (2922159)

“…<p><b>A)</b> Worms injected with ~100ng of SmedCB dsRNA for three consecutive days, followed by amputation (day 0) and three weeks of starvation, showed a marked reduction of SmedCB mRNA when analyzed via RTPCR in comparison to untreated worms. …”

Curcumin inhibits pancreatic cancer cell growth. by Dharmalingam Subramaniam (260271)

“…Curcumin treatment resulted in a significant dose-and time-dependent decrease in cell proliferation in all the cells when compared with untreated controls. …”

Data_Sheet_1_PTEN Expression Regulates Gap Junction Connectivity in the Retina.PDF by Ashley M. Chen (10828518)

“…The number of connexin36 puncta, the predominant connexin that mediates gap junction communication at electrical synapses, was decreased by at least 50% on OFF α-ganglion cells. …”

Comparative analysis of mutant worms and chronological aging effects on forced locomotory abilities. by Xavier Manière (230820)

“…(D) Populations of worms show a decrease of the average velocity as they get older, from the 1^st day (D1) to the 8^th day (D8). …”

Reduced epidermal proliferation and differentiation in skin wounds from Ctip2^ep−/− mice. by Xiaobo Liang (183523)

“…Green and red bars represent Ctip2^L2/L2 and Ctip2^ep−/− mice, respectively. Scale bars: 50 µm (A), 100 µm (B and C).</p>…”

Age and gender effect on MPF, R₁, and ADC. by Jack R. Foucher (5400647)

“…<p><b>a.</b> Upper left graph: Age effect on MPF. All subtypes showed a similar decrease with aging (F(1,22) = 10.6, p = 4 10⁻³, no interaction). …”

Datasheet1_Motor flexibility to stabilize the toe position during obstacle crossing in older adults: an investigation using an uncontrolled manifold analysis.pdf by Yuki Suda (3928037)

“…Introduction<p>An age-related decrease in the ability to exploit the abundant degrees of freedom of the body, referred to as motor flexibility, leads to a heightened fall risk. …”

Nanomechanics of the Endothelial Glycocalyx in Experimental Sepsis by Anne Wiesinger (487509)

“…Corresponding <i>in vitro</i> experiments revealed that sepsis-associated mediators, such as thrombin, LPS or Tumor Necrosis Factor-α alone were sufficient to rapidly decrease eGC thickness (-50%, all P<0.0001) and stiffness (-20% P<0.0001) on HPMEC. …”

Descemet membrane endothelial keratoplasty (DMEK): intraoperative and postoperative complications and clinical results by Yusuf Koçluk (5761517)

“…<div><p>ABSTRACT Purpose: To evaluate the complications and clinical results of Descemet membrane endothelial keratoplasty (DMEK) in patients with endothelial failure that occurred during the learning curve of a surgeon. Methods: Fifty eyes of 50 patients with DMEK and ≥6 months of follow-up were included. …”

Role of voice therapy in adherence to voice rest (King et al., 2021) by Renee E. King (11409101)

“…Coughing and throat clearing were highest in the voice evaluation group and decreased less than talking during voice rest. At follow-up, 84% of participants reported that they completed voice rest for at least as long as recommended and 39.5% reported that they never used their voices during voice rest. …”

Data_Sheet_1_Use of magnetic source imaging to assess recovery after severe traumatic brain injury—an MEG pilot study.PDF by Anand Karthik Sarma (17331364)

“…</p>Methods<p>In this study, we explored the feasibility of conducting resting state magnetoencephalography (MEG) in a case series of sTBI patients acutely after injury (~7 days), and then about 1.5 and 8 months after injury. …”

Plant and Animal Species Activity in Pond and Impermeable Settings by Patricia Agustin (3115977)

“…To be specific, all of these categories will increase/decrease in number in a particular setting. In the case of these settings (pond and impermeable), an increase will occur in the pond setting and a decrease will occur in the impermeable setting.…”

Data_Sheet_1_Association of Serum 25-Hydroxyvitamin D Concentrations With All-Cause and Cause-Specific Mortality Among Adult Patients With Existing Cardiovascular Disease.docx by Lei Dai (261659)

“…</p><p>Methods: We included 37,079 patients with CVD from the UK Biobank study, a prospective cohort of half a million participants aged 40–69 years. …”

Image 1_COP1 drives renal cell carcinoma progression by targeting ACSL4 for ubiquitin-mediated degradation and inhibiting ferroptosis.tif by Yuxiao Zheng (8334027)

“…In vivo, COP1 overexpression accelerated tumor growth in xenograft models, with a 2.5-fold increase in tumor volume compared to controls (p < 0.001), accompanied by reduced ACSL4 expression and elevated Ki67 proliferation index. …”

Identification of Glucose Transporters in <i>Aspergillus nidulans</i> by Thaila Fernanda dos Reis (162684)

“…A tenfold excess of unlabeled maltose, galactose, fructose, and mannose were able to inhibit glucose uptake to different levels (50 to 80 %) in these s. …”

Image_1_Dystrophin Is Required for the Proper Timing in Retinal Histogenesis: A Thorough Investigation on the mdx Mouse Model of Duchenne Muscular Dystrophy.JPEG by Irene Persiconi (453754)

“…Concomitantly, a difference in the time required for the retinal ganglion cell layer to reach appropriate thickness was observed (P0–P5). Immunolabeling for specific cell markers also evidenced a significant dysregulation in the number of GABAergic amacrine cells (P5–P10), a transient decrease in the area immunopositive for the Vesicular Glutamate Transporter 1 (VGluT1) during ribbon synapse maturation (P10) and a reduction in the number of calretinin⁺ retinal ganglion cells (RGCs) (adults). …”

Table_1_Dystrophin Is Required for the Proper Timing in Retinal Histogenesis: A Thorough Investigation on the mdx Mouse Model of Duchenne Muscular Dystrophy.docx by Irene Persiconi (453754)

“…Concomitantly, a difference in the time required for the retinal ganglion cell layer to reach appropriate thickness was observed (P0–P5). Immunolabeling for specific cell markers also evidenced a significant dysregulation in the number of GABAergic amacrine cells (P5–P10), a transient decrease in the area immunopositive for the Vesicular Glutamate Transporter 1 (VGluT1) during ribbon synapse maturation (P10) and a reduction in the number of calretinin⁺ retinal ganglion cells (RGCs) (adults). …”