Constructing gene co-expression networks and predicting functions of unknown genes by random matrix theory-5 by Feng Luo (47640)

“…</p><p>Published online 14 Aug 2007</p><p>PMCID:PMC2212665.</p><p></p> mean of noise is zero and its standard deviation (σ) is set to 1, 2, 5, 10, 20, 30, 40, and 50% of the average of absolute expression value of whole dataset. …”

Bcl-2, Bax, and caspase-3 immunostained sections and morphometric analysis of hepatocytes in the control, PbAc-, IOLE-, and IOLE+PbAc-treated rats. by Ahmed E. Abdel Moneim (3155442)

“…In the IOLE+PbAc group, the number of apoptotic hepatocytes was decreased. (scale bar 50 μm) (B) The plots show an increase in apoptotic hepatocytes in the control, PbAc-, IOLE-, and IOLE+PbAc-treated rats. …”

Effect of replacing beef fat with safflower oil on physicochemical, nutritional and oxidative stability characteristics of wieners by Emel KAYNAKCI (10463779)

“…Incorporation of SO increased CIE L* and b* values, whereas it caused a decrease in CIE a* values of wieners (P < 0.05). …”

Label-free real-time multi-parametric monitoring enables high content analysis. by Heinz-Georg Jahnke (122745)

“…The effect on the APD was determined for one hour after doxorubicin application and revealed a concentration dependent response with an EC₅₀ value of 17 µM (n  = 3 hCMC), (B) The impedance analysis revealed a concentration- and time-dependent decrease where IC₅₀ values could be determined for each time point (n  = 5 hCMC). …”

DataSheet1_Attenuating coherent environmental noise in seismic data via the U-net method.pdf by Yu-Tai Wu (14584727)

Accessibility of IpaC residues from the extracellular surface is altered by the interaction of IpaC with intermediate filaments. by Brian C. Russo (7866425)

Supplementary Material for: First-in-human effects of PPT1 inhibition using the oral treatment with GNS561/ Ezurpimtrostat in patients with primary and secondary liver cancers by Harding J.J. (12088145)

“…Liver trough concentrations were much higher than in plasma a median time of 28 days of administration with a mean liver to plasma ratio of 9559 (Min 149-Max 25759), which is in accordance with rat preclinical data observed after repeated administration. …”

Supplementary Material for: Changes in the Small Bowel of Symptomatic Kidney Transplant Recipients Converted from Mycophenolate Mofetil to Enteric-Coated Mycophenolate Sodium by Bunnapradist S. (4147492)

“…Tacrolimus, MMF and prednisone was the main regimen (94%), with a median MMF dose of 750 mg BID. The average baseline GSRS was 2.99 ± 0.81; it significantly decreased to 2.19 ± 0.8 at 30 days post-conversion. …”

Effects of the demethylating drug 5aza-dC on expression of <i>TMEM131</i> short isoform, <i>TCF7</i>, and <i>NPDC1</i> mRNAs in Jurkat cells and normal human T-cells expanded with... by Kristi Kerkel (237018)

“…The short term cultures of PBMC were grown in the presence of PHA to induce a polyclonal proliferation of T-cells. In each experiment a 25 – 40 percent reduction in DNA methylation of the index regions of interest after exposure to the highest dose of 5aza-dC was confirmed by MS-Pyroseq or bisulfite sequencing (data not shown). …”

PKA activation prevents GABA_B modulation of SK. by Chad M. Estep (3609113)

“…(B) A 50 ms uncaging pulse elicited an immediate and significant change in SOP variance (black, n = 10, Wilcoxon signed rank test, p = 0.002). …”

Interaction between the N-terminus of both caspase 8 and SPARC are required to reduce cell viability and enhance apoptosis. by Mahbuba Rahman (198499)

“…<p><b>A–B</b>) Cell viability further decreased in MIP/SP and MIP/SP-N after transfection with wild-type caspase 8 and 5-FU treatment, relative to empty vector (EV, control): MIP/SP: 77.2±3.8 (EV) vs. 59.1±1.5% (caspase 8) (p<0.005); MIP/SP-N: 68.8±4.8 (EV) vs. 50.6±3.6% (caspase 8) (p = 0.04). …”

Changes in the immunological index after <i>Salacia reticulata</i> extract (SRE) ingestion. by Yuriko Oda (832789)

“…<p>(<b>a</b>) Changes in the T-cell proliferation index from the initial values to the values after 4 weeks are shown in the plot. …”

Kinases are recruited to the signaling complex by alternative N-t localization domains. by Paloma M. Sato (672126)

“…In most cases, mutations that disrupt specific recruitment interactions decrease pathway activation between 40%–50%. MUT Ste20[N]-Ste50[C] might still localize to the signaling complex, as Ste50's RA domain binds Cdc42 independently of Ste20's PBD domain <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1002012#pbio.1002012-Truckses1" target="_blank">[53]</a>. …”

Effect of SARS-CoV-2 Infection and Infection Severity on Longer-Term Glycemic Control and Weight in People With Type 2 Diabetes by Rachel Wong (5544899)

Response gain control by ACh. by Shogo Soma (429657)

“…Gray circles indicate facilitated and suppressed cells whose C₅₀ were decreased or increased by more than 1 SD from the population average, respectively (C, facilitated cells, <i>n</i> = 4; D, suppressed cells, <i>n</i> = 7). …”

Effect of NK depletion on IFN-γ production in tripartite cultures. by Loke Tim Khaw (433343)

Effect of endothelial cells on cytokine production in PBMC/iRBC co-cultures. by Loke Tim Khaw (433343)

MPA and tacrolimus act differentially on the polarization of M1 and M2 macrophages. by Nynke M. Kannegieter (3697594)

“…Tacrolimus changed the expression of M2 markers under a M1-driven condition and decreases the expression of M1 markers under M2 conditions. …”

Tau overload causes behavioral deficits and maintains neurodegeneration at older ages. by Kaushik Ghosal (244754)

“…<p>A. hTau animals also showed decreased working memory as measured by deficits in spontaneous alternations compared to age-matched wild-type animals. …”

Data_Sheet_1_Immediate and long-term electrophysiological biomarkers of antidepressant-like behavioral effects after subanesthetic ketamine and medial prefrontal cortex deep brain... by Matthew Bergosh (18854590)

“…</p>Results<p>We found that the depression-like behavioral and weight effects of CORT correlated with a decrease in aperiodic-adjusted theta power (5–10 Hz) and an increase in sample entropy during the administration phase, and an increase in theta peak frequency and a decrease in the aperiodic exponent once the depression-like phenotype had been induced. …”