Showing 481 - 500 results of 26,875 for search '(( 50 ((nn decrease) OR (a decrease)) ) OR ( 50 ((ng decrease) OR (we decrease)) ))', query time: 0.96s Refine Results
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    A Novel Highly Potent Autotaxin/ENPP2 Inhibitor Produces Prolonged Decreases in Plasma Lysophosphatidic Acid Formation <i>In Vivo</i> and Regulates Urethral Tension by Hiroshi Saga (584103)

    Published 2014
    “…To date, several autotaxin/ENPP2 inhibitors have been reported; however, none were able to completely and continuously inhibit autotaxin/ENPP2 <i>in vivo</i>. In this study, we report the discovery of a highly potent autotaxin/ENPP2 inhibitor, ONO-8430506, which decreased plasma lysophosphatidic acid formation.…”
  4. 484

    GluN2A(D731N) decreases channel open probability. by Kai Gao (120150)

    Published 2017
    “…The di-heteromeric mutant (2A-D731N) and tri-heteromeric receptors with two-copies of the mutant subunit (D731N/D731N) showed a prolonged inhibition rate, reflecting a decreased channel open probability. …”
  5. 485

    Effects of High-Intensity Interval Exercise versus Moderate Continuous Exercise on Glucose Homeostasis and Hormone Response in Patients with Type 1 Diabetes Mellitus Using Novel Ul... by Othmar Moser (789838)

    Published 2015
    “…Before exercise, standardized meals were administered, and short-acting insulin dose was reduced by 25% (A), 50% (B), and 75% (C) dependent on mean exercise intensity. …”
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    Design, Synthesis, and Biological Evaluation of [1,2,5]Oxadiazolo[3,4‑<i>b</i>]pyridin-7-ol as Mitochondrial Uncouplers for the Treatment of Obesity and Metabolic Dysfunction-Assoc... by Mary A. Foutz (20361830)

    Published 2024
    “…Utilizing an oxygen consumption rate assay as a measure of increased cellular respiration, <b>SHO1122147</b> (<b>7m</b>) displayed an EC<sub>50</sub> of 3.6 μM in L6 myoblasts. …”
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    Small Molecule ErbB Inhibitors Decrease Proliferative Signaling and Promote Apoptosis in Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia by Mary E. Irwin (293687)

    Published 2013
    “…In two human Ph+ALL cell lines, inhibition of ErbB kinase activity with canertinib resulted in a dose-dependent decrease in the phosphorylation of an ErbB kinase signaling target p70S6-kinase T389 (by 60% in Z119 and 39% in Z181 cells at 3 µM). …”
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