Showing 1,161 - 1,180 results of 27,284 for search '(( 50 ((nn decrease) OR (a decrease)) ) OR ( 50 ((ng decrease) OR (we decrease)) ))', query time: 0.77s Refine Results
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    Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach by Sneha P. (3926957)

    Published 2017
    “…<div><p>Maturity-onset diabetes of the young type 3 (MODY3) is a non-ketotic form of diabetes associated with poor insulin secretion. …”
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  18. 1178

    Passenger mutations accurately classify human tumors by Marina Salvadores (6589187)

    Published 2019
    “…In particular, introducing the RMD features into a combined classification model increased the fraction of diagnosed patients by 50 percentage points (at 20% FDR). …”
  19. 1179

    Discovery of Novel Substituted <i>N</i>‑(4-Amino-2-chlorophenyl)-5-chloro-2-hydroxybenzamide Analogues as Potent Human Adenovirus Inhibitors by Jimin Xu (2208961)

    Published 2020
    “…Notably, among these derivatives, compound <b>15</b> showed improved anti-HAdV activity (IC<sub>50</sub> = 0.27 μM), significantly decreased cytotoxicity (CC<sub>50</sub> = 156.8 μM), and low <i>in vivo</i> toxicity (maximum tolerated dose = 150 mg/kg in hamster) as compared with niclosamide, supporting its further <i>in vivo</i> efficacy studies for the treatment of HAdV infections.…”
  20. 1180

    CREB Targets Define the Gene Expression Signature of Malignancies Having Reduced Levels of the Tumor Suppressor Tristetraprolin by Mohammad Fallahi (200679)

    Published 2014
    “…These analyses defined a signature of 50 genes differentially regulated between high and low <i>TTP</i>-expressing tumors. …”