Discovery of a Potent and Selective NF-κB-Inducing Kinase (NIK) Inhibitor That Has Anti-inflammatory Effects in Vitro and in Vivo by Zhiqiang Li (102723)

“…Treatment of such diseases with small-molecule NIK inhibitors is a reasonable but underexplored approach. In this paper, we reported the discovery of a potent and selective NIK inhibitor <b>46</b> (XT2). …”

HFD induces LDs and decreases ER and mitochondria in nephrocytes. by Aleksandra Lubojemska (10746241)

“…(<b>E</b>) Low and high magnification views of pericardial nephrocytes (dotted outlines) from STD and HFD larvae, showing that HFD decreases mitochondria (marked with anti-ATP5A) and ER (marked with anti-KDEL) but increases LDs (marked with LipidTOX). …”

Activities of Superoxide Dismutase (SOD), Catalase (CAT) and Peroxidase (POD) enzymes in the inflorescence of two cultivars of cauliflower (<i>Brassica oleracea</i> L.) plants foli... by Munifa Jabeen (12634746)

Likelihood of a decrease in runoff (a), an increase in runoff (b) and a severe change in ecosystems (c) for selected Δ<em>T</em>_g levels by Dieter Gerten (557088)

“…</strong> Likelihood of a decrease in runoff (a), an increase in runoff (b) and a severe change in ecosystems (c) for selected Δ<em>T</em>_g levels. …”

Decreased remyelination initiation is observed in Scribble cKO mice following focal demyelination in corpus callosum. by Andrew A. Jarjour (343100)

“…<i>n</i> = 3 mice per genotype. * <i>p</i> < 0.05, ** <i>p</i> < 0.01, *** <i>p</i> < 0.001 versus Scrib WT CL. Scale bars: A,B,D,E: 2 μm. J,K: 50 μm.</p>…”

Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity by Valentina Noemi Madia (1585285)

“…Most of the designed derivatives were active at micromolar or submicromolar concentration, and the most promising compounds are fluorinated and/or amino acids derivatives <b>13a</b>, <b>14d</b>, and <b>15</b> that showed IC₅₀ 0.16–0.82 μM. …”

Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity by Valentina Noemi Madia (1585285)

“…Most of the designed derivatives were active at micromolar or submicromolar concentration, and the most promising compounds are fluorinated and/or amino acids derivatives <b>13a</b>, <b>14d</b>, and <b>15</b> that showed IC₅₀ 0.16–0.82 μM. …”

Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity by Valentina Noemi Madia (1585285)

“…Most of the designed derivatives were active at micromolar or submicromolar concentration, and the most promising compounds are fluorinated and/or amino acids derivatives <b>13a</b>, <b>14d</b>, and <b>15</b> that showed IC₅₀ 0.16–0.82 μM. …”

Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity by Valentina Noemi Madia (1585285)

“…Most of the designed derivatives were active at micromolar or submicromolar concentration, and the most promising compounds are fluorinated and/or amino acids derivatives <b>13a</b>, <b>14d</b>, and <b>15</b> that showed IC₅₀ 0.16–0.82 μM. …”

Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity by Valentina Noemi Madia (1585285)

“…Most of the designed derivatives were active at micromolar or submicromolar concentration, and the most promising compounds are fluorinated and/or amino acids derivatives <b>13a</b>, <b>14d</b>, and <b>15</b> that showed IC₅₀ 0.16–0.82 μM. …”

Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity by Valentina Noemi Madia (1585285)

“…Most of the designed derivatives were active at micromolar or submicromolar concentration, and the most promising compounds are fluorinated and/or amino acids derivatives <b>13a</b>, <b>14d</b>, and <b>15</b> that showed IC₅₀ 0.16–0.82 μM. …”

Cultured <i>Drosophila</i> S2 cells overexpressing Kat60 exhibit microtubule-disassembly in a concentration-dependent manner. by Kyle D. Grode (725568)

Inhibitory dose of CAP (ID₅₀). by Alan Siu (756300)

“…<p>Duration of CAP treatment necessary to decrease viability by 50%, termed the inhibitory duration (ID_<b>50</b>). …”

Loss of <i>Bmp7</i> results in a decrease in cell proliferation in the cloacal regions, and defects in epithelial stratification. by Kun Xu (116877)

The <i>ΔcchA</i>, <i>ΔmidA</i>, and <i>ΔyvcA</i> strains have decreased accumulation of calcium in the cytoplasm. by Patrícia Alves de Castro (532465)

Time-course analysis of 4AP-induced decrease in GABA_AR- and gephyrin-associated immunofluorescence. by Fumihiro Niwa (168651)

Typical structure of a centrifugal nozzle [25]. by Yanyu Cui (19173181)

“…As temperature rises from 0°C to 50°C, liquid film thickness decreases, with a reduction of 14.6% for low-blending fuel and 52.8% for high-blending fuel.…”

TG6-44 treatment leads to decrease in A/X31-induced cell death in THP-1 cells. by Juan A. De La Cruz (11154187)

Numerical simulation of the time evolution of the interaction between three human plasma proteins and 50∶50 NIPAM/BAM NP with 70 nm diameter. by Daniele Dell'Orco (76455)

There is a significant decrease in fibroblast, α-SMA, and Ly6C staining accompanied with a decrease in proliferation, and increase in cell death in the outflow vein removed <i>Iex-... by Akshaar Brahmbhatt (551498)