[Ca²⁺]_i oscillations during stimulation with 12 mM glucose. by Jurij Dolenšek (276793)

“…Y axis represents the normalized fraction of the difference between maximum and plateau baseline fluorescence. <b>D</b> A pseudo-colored representation of time lags between oscillation end₅₀ in the cell in which [Ca²⁺]_i decreased first and every other cell. …”

DataSheet1_qInward variability-based in-silico proarrhythmic risk assessment of drugs using deep learning model.PDF by Da Un Jeong (13914843)

“…We performed the action potential (AP) simulation using a human ventricular myocyte model to calculate seven in silico features representing the electrophysiological cell states of drug effects over 1,000 beats: qNet, qInward, intracellular calcium duration at returning to 50% baseline (CaD50) and 90% baseline (CaD90), AP duration at 50% repolarization (APD50) and 90% repolarization (APD90), and dVm/dtMax_repol. …”

Shapley Additive Explanations (SHAP) summary plot. by Yue Lv (549862)

Age-Associated Lipidome Changes in Metaphase II Mouse Oocytes by Hyuck Jun Mok (600066)

“…To investigate if aged oocytes display an altered lipidome compared to young oocytes, we performed a global lipidomic analysis between oocytes from 4-week-old and 42 to 50-week-old mice. …”

The PI3K/Akt- and NO-related pathways contribute to EPC tube formation affected by oxLDL. by Feng-Yen Lin (143413)

“…<p>(A and B) EPCs were treated for 2 hours with 0–50 μg/mL oxLDL, then eNOS and Akt activation (phosphorylation) was analyzed by Western blot. …”

Effect of TRPV4-mediated activation of SK3 channels on membrane potential, Vm. by Jonathan Berrout (555482)

“…</b> Effect of TRPV4 activation with GSK101 (50 nM) leading to membrane hyperpolarization of Vm (decreased RFU), as expected for SK3 and BK activation. …”

Image_1.TIF by Yang Q. Xia (4914127)

Image_3.TIF by Yang Q. Xia (4914127)

Image_2.TIF by Yang Q. Xia (4914127)

SPARC-mediated SLUG expression and promotion of melanoma cell migration is PI3K/AKT dependent. by Nina Fenouille (149658)

“…(<b>C</b>) <i>Expression of Myr-AKT protects from SLUG decrease after SPARC depletion:</i> 501mel cells were infected with a control empty adenovirus (AdCMV) or with adenovirus encoding the constitutively active mutant Myr-HA-AKT1 (AdAKT^ca) and transfected 6 hours later with 50 nM siCTRL or siSPARC for 3 days. …”

Table_1_When do bystanders get help from teachers or friends? Age and group membership matter when indirectly challenging social exclusion.DOCX by Ayşe Şule Yüksel (13218042)

“…<p>We examined developmental changes in British children’s (8- to 10-year-olds) and adolescents’ (13- to 15-year-olds, N = 340; Female N = 171, 50.3%) indirect bystander reactions (i.e., judgments about whether to get help and from whom when witnessing social exclusion) and their social-moral reasoning regarding their reactions to social exclusion. …”

Additional file 2 of Nup133 and ERα mediate the differential effects of hyperoxia-induced damage in male and female OPCs by Donna Elizabeth Sunny (9301250)

“…Changes in nuclear envelope proteins in OPCs post hyperoxia. (A) Western blot analysis of male and female OPCs with anti-Nup-50 and anti-Lamin B1 antibodies under normal (3%O2) conditions and post 24 h 80%O2 treatment, showing a significant decrease in expression in the male OPCs. …”

AP-3 knockdown affects newly formed mediator release. by Elaine Zayas Marcelino da Silva (386342)

“…Prostaglandin D2 release (A) was decreased in the AP-3 knockdown cells (ShAP-3 δ Cl.23) while release of leukotriene C4 (B) was unaltered when compared to shRNA control cells (ShCtrl). …”

ATF4 knockdown in the ADRP retinas reduces overall ER stress response (N = 4). by Yogesh Bhootada (408443)

“…The T17M ATF4^+/- retinas were the only group with a significant decrease in peIF2a (P<0.01 as compared to T17M retinas) and increased GADD34 protein levels (<i>P</i><0.05 for all groups). …”

Plot of the modeled association between weight change and activity tracking frequency for both genders, over all activities, and for different monitoring durations. by Arya Pourzanjani (800874)

“…In general, increased monitoring duration is associated with decreased weight loss per month and a weaker association between tracking frequency and weight change. …”

Data from: Effect of macronutrients and fiber on postprandial glycemic responses and meal glycemic index and glycemic load value determinations by Huicui Meng (12708455)

“…</p> <p>Results: Adding carbohydrate to the standard white-bread challenge increased glucose AUCi (P < 0.0001), measured meal GI (P = 0.0066), and mean GL (P < 0.0001). Adding protein (50 g only) decreased glucose AUCi (P = 0.0026), measured meal GI (P = 0.0139), and meal GL (P = 0.0140). …”

Assessment of transcriptome associated with endothelium activation and blood-brain barrier integrity. by Nana O. Wilson (399957)

Sensitivity analysis. by Daniela S Santurio (21030812)

“…For each patient, a constant 50% reduction in each activation mechanism was simulated and the mean reduction in IL6 peak was calculated (reference scenario, black dots, same values as shown in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1012908#pcbi.1012908.g008" target="_blank">Fig 8A</a> fourth panel); this analysis was then repeated by increasing ( + ) and decreasing (–) each parameter in 50% increments.…”

Cell cycle indexes of oNSCs in the developing OE show selective defects in <i>BAF155</i>cKO mutants. by Christina Bachmann (3111933)

“…Scale bars = 25 μm (A) and 50 μm (G–J).</p>…”

Sensitivity of SbV-resistant <i>L. panamensis</i> parasites to edelfosine. by Rubén E. Varela-M (326741)

“…(F) Edelfosine treatment led to a dramatic decrease and amelioration in parasite-induced nose thickness and damage, as shown by photographs from drug-free control and edelfosine-treated hamsters. …”