Inhibition of ACC leads to decreased de novo lipogenesis in both U87 and U87 EGFRvIII but reduced the number of U87 EGFRvIII cells to a greater extent. by Jessica E. C. Jones (541168)

IDD388 Polyhalogenated Derivatives as Probes for an Improved Structure-Based Selectivity of AKR1B10 Inhibitors by Alexandra Cousido-Siah (777034)

“…Next, by means of IC₅₀ measurements, X-ray crystallography, WaterMap analysis, and advanced binding free energy calculations with a quantum-mechanical (QM) approach, we have studied their structure–activity relationship (SAR) against both enzymes. …”

<i>Pax7</i> positive cells decrease during <i>in vitro</i> differentiation of myogenic progenitors. by Cécile Rallière (86527)

Surviving female mice born from DIO or lean dams display a small decrease in rate of intake. by Pedro A. Perez (5807615)

MK-STYX decreases RhoA activation. by Brittany M. Flowers (670483)

DIM contributes to the decrease in membrane polarity of THP-1 during the interaction with <i>M. bovis</i> BCG. by Catherine Astarie-Dequeker (239240)

Proteasome inhibition impairs radiation-induced DNA double strand break (DSB) repair by decreasing homologous recombination. by Kyle R. Cron (455028)

The CtrA level decreases upon depletion of CckA and ChpT. by Oliver Leicht (8755473)

Decreased dendritic spine density in the mature cortex of <i>Cln6^nclf</i> mice. by Jeremy P. Morgan (479017)

The TLR4 activator LPS decreases photoreceptor viability and reducesWnt-mediated protection from oxidative stress. by Hyun Yi (57741)

“…White bars, no H₂O₂; black bars, with H₂O₂. Mean ± SD, *p<0.05 no additions with H₂O₂ (n = 5) compared with Wnt3a (n = 4); #p<0.05 50 µg/ml LPS+Wnt3a (n = 5) compared with Wnt3a+ H₂O₂ (n = 4). …”

Sound stress exposure prolonged the period of decreased withdrawal threshold after complete Freund’s adjuvant (CFA) injection. by Satoka Kasai (3861115)

“…They showed a significant decrease in 50% withdrawal threshold on day 7 after CFA injection, and CFA-treated mice exposed to sound stress showed a significant decrease in 50% withdrawal threshold during days 7–21 after CFA injection (CFA, on day 7, ****<i>P</i> < 0.001 vs day 0, on day 10, ***<i>P</i> < 0.001 vs day0; CFA + stress, day 7, 10, 14, and 21, ****<i>P</i> < 0.0001 vs day 0, Dunnett’s test). …”

Translocation of EHEC-Hly to mitochondria results in cytosolic cytochrome c release and ΔΨ_m decrease. by Martina Bielaszewska (79970)

“…Median fluorescence of OMV-treated cells was expressed as the percentage of the median fluorescence of control untreated cells (defined as 100%). The values represent means ± standard deviations from three independent experiments. * Significantly decreased (<i>p</i><0.05) compared to control cells (unpaired Student's <i>t</i> test). …”

Claudin-18 knockdown by siRNA. (A) Claudin-18 siRNA significantly decreases the mRNA level of claudin-18 in MKN74. by Tadayuki Oshima (461127)

Pharmacologic inhibition of CaMKII and VEGF decreases tumorigenicity of 143B OS cells <i>in vitro</i>. by Paul G. Daft (720351)

Pairwise correlations in APP/PS1 mice are decreased in dCA1, but increased in vCA1. by Udaysankar Chockanathan (18510288)

Decrease in cell migration and adhesion of MCF10A cells after knockdown of <i>MYO1C</i>. by Kittichate Visuttijai (3204519)

“…A dose-dependent decrease in relative cell index response to MYO1C depletion was observed reaching to a significant value with concentrations of 5 and 10 nM of <i>MYO1C</i>-siRNA at 48 hours post-transfection compared to control cells (mock transfection). …”

Imatinib or masitinib decreases cell surface expression of mature c-Kit in UT-7/Epo cell line. by Diane D'allard (405441)

PSD-95 decreases acid-evoked currents in hippocampal neurons, and is dependent upon <i>ASIC2</i>. by Anne Marie S. Harding (546425)

Cofilin concentration selectively decreases in spines following nLTD and involves the capthepsin B/L class of proteases. by Barbara Calabrese (553229)

“…As described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0094787#s2" target="_blank">Methods</a>, a digital processing procedure was used to quantify immunoreactivity only in spine heads (i.e. not the neck or parent dendrite) and also to exclude spines that overlapped with other adjacent structures like astrocytes. …”

Silencing of Rap1A decreases ERK and p38 activation. by Yougen Wu (830191)