Supplementary Material for: A Phase 3 Study of Enarodustat (JTZ-951) in Japanese Hemodialysis Patients for Treatment of Anemia in Chronic Kidney Disease: SYMPHONY HD Study by Akizawa T. (3588626)

“…We conducted a phase 3 study to compare the efficacy and safety of enarodustat with darbepoetin alfa (DA) in Japanese anemic patients with CKD receiving maintenance hemodialysis. …”

Data_Sheet_1_A novel chimeric endolysin Cly2v shows potential in treating streptococci-induced bovine mastitis and systemic infections.docx by Shuang Wang (46453)

“…Notably, in a mouse mastitis model, treatment with Cly2v (50 μg/gland) led to a reduction in bacterial load by 2.16 log₁₀CFU/ml and decreased inflammatory cytokine levels in mammary tissue. …”

Data Sheet 1_Down syndrome burden in China and globally: a comparative analysis of 1990–2021 trends and future projections based on GBD 2021 database.csv by Xiangwen Tu (20471360)

“…</p>Results<p>From 1990 to 2021, China’s ASIR decreased from 1.68 per 100,000 to 1.18 per 100,000, compared to a global reduction from 1.27 per 100,000 to 0.97 per 100,000. …”

Z-stack through a mouse kidney in vivo, showing typical renal structures like glomeruli (g), proximal tubules (pt) and extraglomerular capillaries (arrows). by Ina Maria Schießl (288061)

“…<p>Images were acquired with internal detectors and gain and offset of the detectors were maintained during the imaging process. (A) – (F) show layers in 0, 30, 40, 50, 70, and 100 µm depth underneath the kidney surface. …”

Data_Sheet_1_Soil Microbial Composition and phoD Gene Abundance Are Sensitive to Phosphorus Level in a Long-Term Wheat-Maize Crop System.doc by Ming Lang (3757117)

“…In the present study in the North China Plain, we subjected the bacterial and fungal communities to amplicon sequencing analysis and characterized the alkaline phosphatase gene (phoD) encoding bacterial alkaline phosphatase in a long-term field experiment (10 years) with six mineral P fertilization rates up to 200 kg P ha^–1. …”

Schematic of multiscale biphasic blood flow simulations in the arterial side of the MCA territory. by Grant Hartung (5987810)

Data_Sheet_1_Long-term trends of HIV/AIDS incidence in India: an application of joinpoint and age–period–cohort analyses: a gendered perspective.docx by Neha Shri (12057202)

“…The average annual percentage changes in the incidence were computed, and the age–period–cohort analysis was performed.</p>Results<p>A decreasing trend in the overall estimates of age-standardized HIV incidence rates were observed in the period 1990–2019. …”

Apoptosis inhibitor impeded larval invasion of Caco-2 monolayer. by Qi Qi Lu (17721401)

Table_4_A Network-Based Method for Mechanistic Investigation and Neuroprotective Effect on Post-treatment of Senkyunolid-H Against Cerebral Ischemic Stroke in Mouse.XLSX by Jie Zhang (64655)

“…In this study, we employed network pharmacology to reveal potential mechanism of SEH against CIS on a system level and confirmed the therapeutic effects of SEH on CIS by models of cerebral ischemia-reperfusion in vivo and in vitro. …”

Table_3_A Network-Based Method for Mechanistic Investigation and Neuroprotective Effect on Post-treatment of Senkyunolid-H Against Cerebral Ischemic Stroke in Mouse.XLSX by Jie Zhang (64655)

“…In this study, we employed network pharmacology to reveal potential mechanism of SEH against CIS on a system level and confirmed the therapeutic effects of SEH on CIS by models of cerebral ischemia-reperfusion in vivo and in vitro. …”

Table_7_A Network-Based Method for Mechanistic Investigation and Neuroprotective Effect on Post-treatment of Senkyunolid-H Against Cerebral Ischemic Stroke in Mouse.XLSX by Jie Zhang (64655)

“…In this study, we employed network pharmacology to reveal potential mechanism of SEH against CIS on a system level and confirmed the therapeutic effects of SEH on CIS by models of cerebral ischemia-reperfusion in vivo and in vitro. …”

Image_3_Evolving trends and burden of iron deficiency among children, 1990–2019: a systematic analysis for the global burden of disease study 2019.TIF by Dan Long (151972)

“…Objectives<p>We aimed to provide a timely, comprehensive, and reliable assessment of the burden of iron deficiency (ID) in children between 1990 and 2019 at the global, regional, and national levels to inform policymakers in developing locally appropriate health policies.…”

Image_2_Evolving trends and burden of iron deficiency among children, 1990–2019: a systematic analysis for the global burden of disease study 2019.TIF by Dan Long (151972)

“…Objectives<p>We aimed to provide a timely, comprehensive, and reliable assessment of the burden of iron deficiency (ID) in children between 1990 and 2019 at the global, regional, and national levels to inform policymakers in developing locally appropriate health policies.…”

Table_2_A Network-Based Method for Mechanistic Investigation and Neuroprotective Effect on Post-treatment of Senkyunolid-H Against Cerebral Ischemic Stroke in Mouse.XLSX by Jie Zhang (64655)

“…In this study, we employed network pharmacology to reveal potential mechanism of SEH against CIS on a system level and confirmed the therapeutic effects of SEH on CIS by models of cerebral ischemia-reperfusion in vivo and in vitro. …”

Data_Sheet_1_Spatial Stability of Functional Networks: A Measure to Assess the Robustness of Graph-Theoretical Metrics to Spatial Errors Related to Brain Parcellation.pdf by Francesca Bottino (12103367)

“…Two brain parcellations were performed using FreeSurfer with geometric atlases. Starting from these, 100 new parcellations were created by increasing the area of 30% of parcels, reducing the area of neighbour parcels, with a rearrangement of vertices. fMRI data were filtered with linear regression, CompCor, and motion correction. …”

Table_5_A Network-Based Method for Mechanistic Investigation and Neuroprotective Effect on Post-treatment of Senkyunolid-H Against Cerebral Ischemic Stroke in Mouse.XLSX by Jie Zhang (64655)

“…In this study, we employed network pharmacology to reveal potential mechanism of SEH against CIS on a system level and confirmed the therapeutic effects of SEH on CIS by models of cerebral ischemia-reperfusion in vivo and in vitro. …”

Table_6_A Network-Based Method for Mechanistic Investigation and Neuroprotective Effect on Post-treatment of Senkyunolid-H Against Cerebral Ischemic Stroke in Mouse.XLSX by Jie Zhang (64655)

“…In this study, we employed network pharmacology to reveal potential mechanism of SEH against CIS on a system level and confirmed the therapeutic effects of SEH on CIS by models of cerebral ischemia-reperfusion in vivo and in vitro. …”

Image_1_Evolving trends and burden of iron deficiency among children, 1990–2019: a systematic analysis for the global burden of disease study 2019.TIF by Dan Long (151972)

“…Objectives<p>We aimed to provide a timely, comprehensive, and reliable assessment of the burden of iron deficiency (ID) in children between 1990 and 2019 at the global, regional, and national levels to inform policymakers in developing locally appropriate health policies.…”

Table_1_A Network-Based Method for Mechanistic Investigation and Neuroprotective Effect on Post-treatment of Senkyunolid-H Against Cerebral Ischemic Stroke in Mouse.XLSX by Jie Zhang (64655)

“…In this study, we employed network pharmacology to reveal potential mechanism of SEH against CIS on a system level and confirmed the therapeutic effects of SEH on CIS by models of cerebral ischemia-reperfusion in vivo and in vitro. …”

Data_Sheet_1_Potential Role of Dissolved Oxygen and Manganese Concentration on the Development of Biofilms Causing Reduction in Hydraulic Capacity of a Gravity-Fed Irrigation Syste... by Alno Carstens (9359114)

“…This decrease in Mn concentration with distance suggests that biofilm accumulation has not yet reached a steady state. …”