Metabolic profiling by tandem mass spectrometry reveals distinct metabolite signatures of cells exposed to pro-inflammatory cytokines vs. the apoptotic inducer camptothecin. by J. Jason Collier (130356)

“…<p><i>A</i>. 832/13 cells were exposed to 1 ng/mL IL-1β+100 U/mL γ-IFN or 2 µM camptothecin for 6 h. …”

K_v4 is Required for Maintaining Excitability in <i>Drosophila</i> Neurons. by Yong Ping (233004)

“…<p><i>A</i>, Representative firing patterns recorded with current injections of 40, 60, and 100 pA from wild-type (wt) and DNK_v4 (DN) neurons. …”

Fasting Conceals Rapid Diet-Induced Inhibition of PDH. by Clair Crewe (467358)

“…Mitochondria were incubated with 100 µM pyruvate and 1.0 mM malate. State 3 respiration was initiated by addition of 0.25 mM ADP. …”

Bromatological quality of silage from cassava residues: fractionation of proteins and carbohydrates by Leones Costa dos SANTOS (6131006)

“…<div><p>ABSTRACT The objective of this study was to evaluate the quality of silage in the upper third of cassava levels of inclusion of cassava peel, 0, 100, 200, 300, 400 g/kg out based on natural matter (NM) with 60 days of storage on fermentative profile, aerobic stability, chemical composition and protein and carbohydrate fractionation. …”

Increased Autophagy in <i>daf-2/</i>insulin/IGF Receptor Mutants Is Independent of the <i>daf-16</i>/FOXO and <i>pha-4</i>/FOXA Transcription Factors by Malene Hansen (10367)

“…The mean lifespan of <i>daf-2(e1370)</i> animals was shortened 12.5% by <i>pha-4</i> RNAi ([<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.0040024#pgen-0040024-b028" target="_blank">28</a>] and data not shown), and we measured an 11% decrease in puncta in <i>daf-2(e1370)</i> animals fed <i>pha-4</i> RNAi. …”

Requirement of viral DNA replication for sT-mediated late gene reporter activation in MCV reporter viral genomes. by Kyle Rapchak (13833941)

“…<b>(B)</b> Quantification of late gene-driven ZsG positive cells (top panel) and mean fluorescence intensity (bottom panel). Cells obtained from 6 independent transfections were analyzed by flow cytometry. sT deletion does not significantly decrease ZsG positive cells whereas introducing a mutation into the NCCR (MCVΔsT.L-ZsG_rep-) decreased percent positivity by 50%. …”

Statistical description of the activity in excitatory-inhibitory networks with external and spiking noise. by Francesca Mastrogiuseppe (3947603)

“…Increasing the time constant of rate dynamics (see <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1005498#pcbi.1005498.e079" target="_blank">Eq (50)</a> in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1005498#sec019" target="_blank">Methods</a>) decreases the amplitude of spiking noise. …”

Normal morphology of doublecortin-positive neurons after environmental enrichment in APP_Sw,Ind mice. by Jorge Valero (230721)

“…(D) The number of nodes, which is significantly increased at 50 µm and reduced at 100 µm from the soma in APP_Sw,Ind mice, is normalized by enrichment. …”

Fig 3 - by Katharina Rump (2224759)

“…B) ELISA showed that histone H3 lysine 4 di-methylation (H3K4me2) decreased in U343 cells after incubation with 250 ng/ml midazolam (n = 3; p = 0.02) C) Chip-Assay confirmed binding of <i>BCHE</i> promoter region (90 bp) to H3K4me2; a 100 bp DNA Ladder was utilized; lanes 1, 7 show incubation with H3K27 antibody; lanes 2 and 6 show incubation with H3K4 antibody; lane 4 shows negative control without antibody and lane 5 shows positive control with RNA-polymerase II antibody (two experiments out of three are shown; n = 3). …”

An early Env engineered to have weak, medium, or tight binding to CD4 becomes progressively more promiscuous in its use of primate CD4 receptors. by Cody J. Warren (563898)

“…Error bars are not plotted in instances in which the size of the error bar is less than the symbol size. IC₅₀ values are listed on each panel, for which the mean and SD values reflect the variation of the IC₅₀ calculations from two independent experiments. …”

Amplitude and phase images of PLA beads in water observed by the IP-SEM system. by Toshihiko Ogura (131016)

“…<p>(A) and (B): Amplitude (A) and phase (B) images of 500 nm-diameter PLA beads in water, simultaneously obtained from the lock-in amplifier (EB acceleration voltage 7 kV, EB current 300 pA, input frequency 50 kHz, magnification 200×). …”

Epidemiology of HPV 16 and Cervical Cancer in Finland and the Potential Impact of Vaccination: Mathematical Modelling Analyses by Ruanne V Barnabas (16126)

“…If older women are more likely to have persistent infections and progress to cancer, then vaccination with a duration of protection of less than 15 y could result in an older susceptible cohort and no decrease in cancer incidence. …”

TPMP inhibits mitochondrial respiration and increases glycolytic activity in intact C2C12 cells. by Moustafa Elkalaf (441286)

“…The inhibitory effect following TPMP treatment is demonstrated by a gradual dose-dependent decrease in cellular OCR. Data is expressed as the percentage of basal OCR (OCR%) and is presented as means ±95% CI, n = 4, measured in triplicate. …”

Effects of SIL treatment on HCC cell viability and morphology. by Song Zhang (180477)

“…<p><b>A.</b> Cells were treated with SIL at different concentrations (50, 100, and 200 µM) and assessed at different time points (12, 24, and 48 h). …”

The effect of mycophenolic acid (MPA) and guanosine (Gua) on HCV infectious progeny production and intracellular nucleotide pools. by Ana M. Ortega-Prieto (446894)

“…(b) Left: Intracellular amount of the four nucleoside-triphosphates, following 72 h of exposure to either MPA or Gua, as indicated at the bottom. Right: decrease or increase of nucleotide concentration as a result of exposure to Gua or MPA; note that the maximum decrease possible is 100%. …”

Magnitude of within-object color coding within each CNN layer. by JohnMark Taylor (8329326)

“…Regression analyses were conducted to test for an aggregate increase or decrease in color representation over the course of processing; upward- and downward-facing arrows denote a significant increase or decrease respectively, with the level of significance denoted by the adjacent asterisks. …”

Rapamycin improved CA1 dendritic arborization and spine density in hippocampi from rats subjected to SE. by Amy L. Brewster (388121)

“…Scale bar = <b>A</b>: 100µm; <b>D</b>: 5µm. * compared to Sham+Veh, <i>P<</i>0.05; † compared to SE+Veh, <i>P<</i>0.05, ANOVA with Tukey’s <i>post hoc</i> test. …”

6-OHDA lesion-induced dopamine depletion increases intrinsic excitability of medium spiny neurons. by Karima Azdad (370732)

“…(D) Summary histogram of the mean first spike latency at the 120 pA current pulse illustrating the decrease of the first spike latency induced by 6-OHDA lesion. …”

Representative immunolabeling for insulin, glucagon, caspase-3, PCNA, Trx1 and Prx2 in pancreatic islets in water (W), regular cola (C) and light cola (L) groups. by Matilde Otero-Losada (543304)

“…In addition, the cytoplasmic expression of glucagon showed a transient decrease at 6 months which recovered at 12 months. …”

Production and characterization of gypsum-based composites reinforced with cocoa agroindustry waste particles by Maria Cecíllia Ramos de Araújo Veloso (10472934)

“…As for the mechanical properties, there was a decrease in resistance both to flexion (3.60 to 0.84 MPa) and to compression (4.43 to 1.73 MPa). …”