Oxidative stress-induced Akt downregulation mediates green tea toxicity towards prostate cancer cells by Posadino, Anna Maria

“…Treatment of PC3 cells with 30 and 100μg/ml PE significantly decreased cell viability and proliferation. …”
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Palmitate diet causes systolic dysfunction in 12 weeks. by Catherine J. Knowles (400844)

“…No differences were observed in diastolic contractile performance. Means ± SE, n = 4–8 (50/50 gender split in all groups), linear regression analysis through single data points using GraphPad Prism 4.…”

Epidemiology of herpes simplex virus type 2 in sub-Saharan Africa: Systematic review, meta-analyses, and meta-regressions by Harfouche, Manale

“…Pooled HSV-2 proportion in genital ulcer disease was 50.7% (95% CI: 44.7–56.8%) and in genital herpes it was 97.3% (95% CI: 84.4–100%). Interpretation: Seroprevalence is declining by 2% per year, but a third of the population is infected. …”
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Data Sheet 1_EURAD state-of-the-art report: thermo-hydro-mechanical behaviour of clay buffers at high temperatures.pdf by María Victoria Villar (20955281)

“…<p>Most safety cases for radioactive waste disposal consider a temperature limit of 100°C for the clay buffers. …”

Data Sheet 1_The global, regional, and national patterns of change in the burden of edentulism, 1990–2021: an analysis of the global burden of disease study 2021 and forecast to 20... by Xiaolan Zhong (701647)

“…</p>Results<p>Globally, the age-standardized incidence rate (ASIR) decreased from 328.85 (95% UI: 268.72–396.35) per 100,000 in 1990 to 305.04 (95% UI: 261.19–356.58) in 2021, with an estimated annual percentage change (EAPC) of −0.23% (95% CI: −0.33% to −0.14%), indicating a long-term decline. …”

Micro-scale Spatial Clustering of Cholera Risk Factors in Urban Bangladesh by Qifang Bi (2151490)

“…Strong spatial clustering of exposures at a small spatial scale in a cholera endemic population suggests a possible role for highly targeted interventions. …”

COMPARE-MS assay performance by Srinivasan Yegnasubramanian (27577)

“…The degree of capture of unmethylated DNA (untreated WBC DNA) in the presence of MBD2-MBD is less than or equal to the capture of DNA in the absence of MBD2-MBD or anti-His antibody, showing that capture of unmethylated DNA during the DNA capture step of COMPARE-MS is almost completely due to low amounts of non-specific binding to the protein G magnetic beads, as opposed to low-level binding of the MBD2-MBD to unmethylated DNA. () Plots showing the measured amount of methylated CGIs in M.SssI treated and untreated WBC genomic DNA versus the amount of input DNA after enriching for methylated DNA by the combination of methylation-sensitive restriction enzyme digestion and MBD2-MBD capture (COMPARE-MS) followed by real-time PCR. When 20–100 ng of input DNA are used, COMPARE-MS has a >5000-fold dynamic range, which is ∼500-fold higher than that of methylation-sensitive restriction enzyme used alone and ∼5- to 10-fold higher than that of MBD2-MBD capture used alone. () Plot showing measured output methylated CGIs as determined by COMPARE-MS when decreasing amounts of M.SssI-treated WBC DNA is diluted in 20 ng of untreated WBC genomic DNA. …”

Mutation-intolerant IDRs carry characteristic UniProt features compared to relatively tolerant IDRs. by Shehab S. Ahmed (12231721)

“…The horizontal dashed line at OR = 1.0 indicates no association between a residue type and a feature. To facilitate the visualization, minimum and maximum values of OR along the y-axis are set to 0.05 and 10.0, respectively. …”

The evolution of color space similarity among objects across CNN layers and the dependence of color space similarity on object form similarity. by JohnMark Taylor (8329326)

“…Results for random networks are averaged across 100 random initializations of the network. c. A schematic illustration of comparing color space similarity and object form similarity, using the same notations as those in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0253442#pone.0253442.g002" target="_blank">Fig 2A</a>. …”

Linking neural data with behavioral data in the EVA framework. by Quynh-Anh Nguyen (847240)

“…Averaged spike counts over <i>N</i>_<i>in</i> A1-neurons, , are normal-like distributed with means <i>m</i>_<i>DF</i> and standard deviation decreasing inversely with ; shown in gray (<i>DF</i> = 3), black (<i>DF</i> = 5) and light-gray (<i>DF</i> = 7) for <i>N</i>_<i>in</i> = 10 (upper panel) and <i>N</i>_<i>in</i> = 100 (lower panel). …”

Metabolic signature of aging and longevity in serum as per LC/MS eicosanoids profiling. by Sebastiano Collino (385873)

“…<p>Reported is median value in ng/100 µl serum among the three age groups. Blue denotes negative/decreased concentration, orange denotes positive/increased correlation, black denotes no changes. …”

Neuronal cells expressing the cGMP gated cation channel TAX-2/TAX-4 are required to modulate the effect of neuronal stress on fat-remodeling in the intestine. by Laetitia Chauve (8600553)

“…This allele causes a partial rescue (50%) of <i>hsf-1</i>^<i>neuro</i> fat stores. …”

Influence of exosomes on sensitivity of cells to cisplatin. by Xia Xiao (432173)

“…Images were obtained at a magnification of 100×. *in (A) indicates p<0.05 versus control groups.…”

FRET changes induced by mAChR orthosteric and allosteric agonists in HEK293-M₁-cam5 cells. by Danijela Markovic (153328)

“…<p>Addition of arecoline (<b>A</b>; 300 µM), pilocarpine (<b>B</b>; 300 µM), 77-LH-28-1 (<b>C</b>; 10 µM) and AC-42 (<b>D</b>; 30 µM) induced decreases in FRET, which remained constant until reversal by addition of atropine (1 µM). …”

Differentially expressed genes related to inflammatory response and validation of <i>stat3</i> expression in uninjured and injured zebrafish spinal cord. by Subhra Prakash Hui (510710)

“…The value represented as Mean±SEM of individual longitudinal section, n = 5 cord, p<0.01.Scale bar = 200 µm (C–D); 50 µm (E–P), 20 µm (Q–X).…”

Detailed evaluation of the automated cell counting method. by Nafiseh Atapour (19727499)

“…Among the 2,216 empty image patches, 50% had a residual density less or equal to 70 mm^-3, and the mean residual density amounted to 170 mm^-3, which shows that the impact of the background on the U-Net CNN results is negligible. …”

Attention reduces decision uncertainty under high cognitive demand. by Rahul Garg (3064578)

“…The cue was omitted in 50% of the trials during test session. Inter-trial interval (ITI) varied between 15 and 45 s. …”

Tuning of Msn2 expression in rapidly growing cells. by Michal Chapal (7961111)

“…(F–G) Noisy Msn2 expression decreases stress protection and growth rate: we generated six strains with Msn2-YFP expressed under different promoters, which control genes with noisier expression than Msn2 but have a similar mean abundance (mean abundance in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000289#pbio.3000289.s005" target="_blank">S5 Fig</a>), and deletion of <i>MSN4</i>. …”

Effect of TCERG1 knockdown on Fas-mediated apoptosis. by Marta Montes (812749)

“…Control and TCERG1 knockdown (KD) Jurkat cells were incubated with annexin-V and analyzed by flow cytometry in the absence (-) or presence (+) of 50 ng/ml of anti-Fas/CD95 for 6 h. The bar graph shows the percentage of annexin-V positive cells from three independent experiments (means ± SEM). *, <i>p</i> < 0.05. …”

Reduction of mitotic neural progenitors in the ventricular zone of the nCT brain. by Sunny Li-Yun Chang (275903)

“…Scale bars in A1 (for A1, A2), 50 µm; B1 (for B1, B2), 100 µm; C1 (for C1, C2), 200 µm.…”