Search alternatives:
nn decrease » _ decrease (Expand Search), gy decreased (Expand Search), b1 decreased (Expand Search)
c decrease » c decreased (Expand Search), _ decrease (Expand Search), rc decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
nn decrease » _ decrease (Expand Search), gy decreased (Expand Search), b1 decreased (Expand Search)
c decrease » c decreased (Expand Search), _ decrease (Expand Search), rc decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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GCase activity is significantly decreased in the brain and liver of the homozygous <i>GBA1</i> D409V KI mouse model at 4, 8, and 12 months of age.
Published 2021“…In whole brain homogenate (A,C) and liver homogenate (B,D), GCase activity is significantly decreased in the <i>GBA1</i> D409V KI homozygous (HOM) mice as compared to C57Bl/6 wild type (WT) mice (n = 7/group). …”
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Glucose depletion decreases SBPM.
Published 2019“…<b>C)</b> Only the metabolically active D-isoform of glucose (not L-glucose) can sustain a significantly higher SBPM in physiologically-relevant conditions containing 5mM D- or L-glucose, 5mM DL-lactate (racemic mixture) and 0.22mM pyruvate. …”
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Cumulative effects and geographic distribution of mCHG-decreasing alleles.
Published 2022“…<b>(D)</b> The number of recent transposon insertions [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1010345#pgen.1010345.ref022" target="_blank">22</a>] as a function of <i>NRPE1’</i> genotype and the number of mCHG-decreasing alleles. …”
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Juvenile demyelination leads to a decrease in axonal complexity of PFC PV interneurons.
Published 2025“…</b> Quantification of the overall myelin intensity in PFC of both groups shows a clear loss of myelin in the juvenile demyelination group (<i>t test; n = 6/5 mice per group, ***p < 0.001</i>). …”
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Cardamonin inhibited tumor growth and decreased FASN and Raptor.
Published 2025“…Cardamonin reduces the protein expression of Raptor, thereby inhibiting the mTORC1-regulated DNL pathway. This leads to a decrease in free fatty acid levels. Subsequently, the reduced levels of free fatty acids inhibit the activity of mitochondrial CPT-1 and induces mitochondrial dependent apoptosis. …”
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Nimodipine does not decrease markers of neuritic dystrophy in 5XFAD transgenic mice.
Published 2022“…<p><b>(</b>A and F) Representative immunoblots of hippocampal (A) and cortical (F) lysates of non-transgenic and 5XFAD mice treated with vehicle or nimodipine. …”
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IL-15 decreased early apoptosis of α-GalCer-treated iNKT cells in SLE patients.
Published 2021Subjects: -
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Adaptation to cool temperature decreases basal and stimulated lipolysis and increases <i>de novo</i> lipogenesis and TAG synthesis.
Published 2021“…(<b>H</b>) Quantification of autoradiography for labeled TAG was by ImageJ. <i>n =</i> 5, data are mean ± SD. *<i>p</i> < 0.05. Uncropped western blots are provided in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000988#pbio.3000988.s016" target="_blank">S1 Raw Images</a>, and numerical data for all graphs are provided in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000988#pbio.3000988.s014" target="_blank">S6 Data</a>. …”
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