Showing 421 - 440 results of 102,833 for search '(( 50 ((nn decrease) OR (mean decrease)) ) OR ( 5 ((mg decrease) OR (a decrease)) ))', query time: 1.38s Refine Results
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    OCA alone markedly decreases and combined with Gemcitabine or Cisplatin abrogates growth of iCCA xenografts. by S. Di Matteo (6260417)

    Published 2019
    “…After 4 weeks, when the tumor size was approximately 100 mm<sup>3</sup> (T<sub>0</sub>) mice were treated with OCA (0.03% w/w, 30 mg/kg) alone or combined with Cisplatin (2.4 mg/Kg in 100 μl) or Gemcitabine (1.05 mg/Kg in 100 μl) for 5 additional weeks. a) Results are expressed as percent increase in tumor volume at different time points. …”
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    Treatment with proteasome inhibitor bortezomib decreases organic anion transporting polypeptide (OATP) 1B3-mediated transport in a substrate-dependent manner by Khondoker Alam (1443499)

    Published 2017
    “…Compared with vehicle control treatment, bortezomib pretreatment significantly decreased the maximal transport velocity (V<sub>max</sub>) of OATP1B3-mediated transport of CCK-8 (92.25 ± 14.2 vs. 133.95 ± 15.5 pmol/mg protein/min) without affecting the affinity constant (K<sub>m</sub>) values. …”
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