Table_1_Uncovering the Mechanisms of Cryptotanshinone as a Therapeutic Agent Against Hepatocellular Carcinoma.xlsx by Yi Luo (143206)

“…In addition, we found that CPT induced apoptosis in Huh7 and MHCC97-H ells due to increased levels of cleaved PARP, Bax, and cleaved caspase-3 and decreased Bcl-2 expression. CPT also induced autophagy in HCC cells by increasing LC3-II conversion and the expression of Beclin1 and ATG5, while decreasing the expression of p62/SQSTM1. …”

Efficacy of Rifampin Plus Clofazimine in a Murine Model of <i>Mycobacterium ulcerans</i> Disease by Paul J. Converse (227430)

“…Footpad swelling declined comparably with all of the combination regimens, as did the levels of detectable mycolactone A/B. In mice treated for only 6 weeks and followed up for 24 weeks, there were no relapses in RIF+STR treated mice, one (5%) relapse in RIF+CFZ-treated mice, but >50% in RIF+CLR treated mice. …”

Cyclin G2 is an unstable protein and can be degraded through a calcium-mediated mechanism. by Stefanie Bernaudo (4167634)

“…Cells were lysed and Western blot analyses were performed. Treatment with A23187 decreased the levels of full length and PEST-24 cyclin G2 while the protease inhibitor, ALLN, protected cyclin G2 from degradation. …”

Table_2_Uncovering the Mechanisms of Cryptotanshinone as a Therapeutic Agent Against Hepatocellular Carcinoma.xlsx by Yi Luo (143206)

“…In addition, we found that CPT induced apoptosis in Huh7 and MHCC97-H ells due to increased levels of cleaved PARP, Bax, and cleaved caspase-3 and decreased Bcl-2 expression. CPT also induced autophagy in HCC cells by increasing LC3-II conversion and the expression of Beclin1 and ATG5, while decreasing the expression of p62/SQSTM1. …”

(A) FACS measurements of mitochondrial membrane potentials in wt, P1b, and P0 cells exposed to MitoTracker by Lilli Winter (93188)

“…(I) Evaluation of mitochondrial fluorescence decrease over time. Values represent mean ± SEM. = 50 (wt), 47 (P1b), and 53 (P0) ROIs analyzed. …”

Pyruvate oxidase-deficiency increases susceptibility of <i>Spn</i> to OSCN^-. by Aaron D. Gingerich (9188396)

“…<b>(B)</b> OSCN^—mediated (1st line™) killing of the TIGR4 Δ<i>spxB Spn</i> strain was measured by the microplate-based growth assay in presence or absence of catalase (n = 5). Each symbol represents a separate, individual experiment, mean+/-S.E.M. is shown. …”

Disentangling the Association between Statins, Cholesterol, and Colorectal Cancer: A Nested Case-Control Study by Ronac Mamtani (2626705)

“…The association between decreased serum cholesterol and colorectal cancer risk suggests a cholesterol-lowering effect of undiagnosed malignancy. …”

NHR-49 has a broad impact on fatty-acid desaturation in germline-less animals. by Ramesh Ratnappan (128556)

“…</b> mRNA levels of <i>fat-5</i> (A), <i>fat-6</i> (B) and <i>fat-7</i> (C) were compared by Q-PCRs between day 2 adults of the following strains: wild-type (N2, gray), <i>nhr-49</i> (blue), <i>glp-1</i> (green) and <i>nhr-49</i>;<i>glp-1</i> (maroon). …”

Supplementary Material for: Trends in the Incidence of Rare Eyelid Malignancies: A SEER-Based Study (2000–2021) by figshare admin karger (2628495)

The Role of Qatar Community Pharmacists in Depression care: A Survey of Attitudes, Practices and Perceived Barriers by Shami, Rula

“…Responses were measured on a 5-point-Likert scale. Study outcomes were scores of attitudes towards depression, scores of self-reported depression care practices and perceived barriers for depression care. …”
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Table_3_Parent post-traumatic growth after a child's critical illness.DOCX by Lauren M. Yagiela (13879031)

“…Median age of their children was 2.8 years (IQR 0.5–11.3) with a median hospital stay of 12 Days (IQR 6–20). …”

RNAi of a subset of pairing promoters causes Cap-H2–dependent pairing disruption. by Eric F. Joyce (165338)

“…<p>a, Representative FISH images are shown for RNAi knockdown of candidate pairing promoters <i>slmb</i> and <i>pav</i>, where the number of single-signal dodeca FISH signals per nucleus (noted) is decreased as compared to <i>lacZ</i> RNAi control (<i>P</i><0.05). …”

Table_1_Profound Perturbation in the Metabolome of a Canine Obesity and Metabolic Disorder Model.xlsx by Weiyi Qu (5693201)

“…A total of 132 urine metabolites related to HFD-induced obesity and metabolic disorders were identified, including 3-methylxanthine, theophylline, pyridoxal 5’-phosphate, and harmine, which participate in pathways such as caffeine metabolism and vitamin digestion and absorption. …”

Image_1_Cyclophosphamide augments the efficacy of in situ vaccination in a mouse melanoma model.tif by Noah Tsarovsky (15174500)

“…</p>Methods<p>Treatments with RT (12Gy) and/or CY (100 mg/kg i.p.) started when tumors reached 100-300 mm³ (day 0 of treatment), followed by five daily injections of IT-IC (25 mcg) on days 5-9. …”

Supplementary Material for: Prevalence of Driving and Traffic Accidents among People with Seizures: A Systematic Review by Xu Y. (3230514)

“…Prevalence of traffic accidents ranged from 0 to 61% following seizure onset, or in the past 1–5 years. The percentage of people with seizures who drove decreased as time since diagnosis increased (<i>p</i> = 0.01, adjusted <i>R</i>² = 31%). …”

Phylodynamics of HIV-1 from a Phase III AIDS Vaccine Trial in Bangkok, Thailand by Marcos Pérez-Losada (159353)

“…The relative genetic diversity of the HIV-1 population has remained high despite decreasing prevalence rates since the mid 1990s.</p> <h3>Conclusions</h3><p>Our study and recent epidemiological reports indicate that HIV-1 is still a major threat in Thailand and suggest that HIV awareness and prevention needs to be strengthened to avoid AIDS resurgence.…”

Image_3_Cyclophosphamide augments the efficacy of in situ vaccination in a mouse melanoma model.tif by Noah Tsarovsky (15174500)

“…</p>Methods<p>Treatments with RT (12Gy) and/or CY (100 mg/kg i.p.) started when tumors reached 100-300 mm³ (day 0 of treatment), followed by five daily injections of IT-IC (25 mcg) on days 5-9. …”

Table_2_Profound Perturbation in the Metabolome of a Canine Obesity and Metabolic Disorder Model.xlsx by Weiyi Qu (5693201)

“…A total of 132 urine metabolites related to HFD-induced obesity and metabolic disorders were identified, including 3-methylxanthine, theophylline, pyridoxal 5’-phosphate, and harmine, which participate in pathways such as caffeine metabolism and vitamin digestion and absorption. …”

Table_2_Parent post-traumatic growth after a child's critical illness.DOCX by Lauren M. Yagiela (13879031)

“…Median age of their children was 2.8 years (IQR 0.5–11.3) with a median hospital stay of 12 Days (IQR 6–20). …”

Image_2_Cyclophosphamide augments the efficacy of in situ vaccination in a mouse melanoma model.tif by Noah Tsarovsky (15174500)

“…</p>Methods<p>Treatments with RT (12Gy) and/or CY (100 mg/kg i.p.) started when tumors reached 100-300 mm³ (day 0 of treatment), followed by five daily injections of IT-IC (25 mcg) on days 5-9. …”