Toll-Like Receptor 9 Deficiency Protects Mice against <i>Pseudomonas aeruginosa</i> Lung Infection by Fatima BenMohamed (530333)

“…<div><p><i>Pseudomonas aeruginosa</i> is an opportunistic pathogen involved in nosocomial infections. While a number of studies have demonstrated the roles of TLR2, TLR4 and TLR5 in host defense againt <i>P. aeruginosa</i> infection, the implication of TLR9 in this process has been overlooked. …”

Internet-Delivered Cognitive Behavior Therapy for Adolescents with Obsessive-Compulsive Disorder: An Open Trial by Fabian Lenhard (581252)

“…Treatment yielded significant improvements on all clinician-, parent- and most self-administered outcome measures, with a large effect size of <i>d</i> = 2.29 (<i>95% CI</i> 1.5–3.07) on the CY-BOCS. …”

Table_3_Complete and rapid regeneration of fragments from the upside-down jellyfish Cassiopea.xlsx by Malte Ostendarp (13217973)

“…Over a total observation period of 5 weeks, we regularly monitored survival, pulsation behavior, growth and the regeneration pattern of fragments. …”

RGMb is not essential for AMH signalling in granulosa cells. by Lauriane Sèdes (490693)

“…Western blot with a phospho-Smad1/5/8 antibody (E, n = 4) and real-time PCR on <i>Id3</i> gene (G, n = 6) showed that the knowkdown of <i>Rgmb</i> does not affect AMH signalling pathway. …”

Table_1_Complete and rapid regeneration of fragments from the upside-down jellyfish Cassiopea.docx by Malte Ostendarp (13217973)

“…Over a total observation period of 5 weeks, we regularly monitored survival, pulsation behavior, growth and the regeneration pattern of fragments. …”

Climate and air pollution impacts on habitat suitability of Austrian forest ecosystems by Thomas Dirnböck (4430077)

“…In future, climate-driven shifts (and losses) in the species potential distribution, but also N driven nutrient enrichment may threaten these habitats. We applied a dynamic geochemical soil model (VSD+) together with a novel niche-based plant response model (PROPS) to 5 forest habitat types (18 forest sites) protected under the EU Directive in Austria. …”

Clinical and Economic Outcomes of the Minimalist Approach for Transcatheter Aortic Valve Replacement by Marcus R. Burns (6179597)

“…In comparison to control patients, those who had TAVR with MP had shorter median hospital length-of-stay (LOS) (2.0 days [1.6, 2.7] vs. 3.0 days [2.0, 5.1]; <i>p</i> < 0.001). Implementation of MP was associated with a significant decrease in total variable costs of 17.9%, an increase in patients with a positive contribution margin (from 30% in 2015 to 65% in 2017), and cumulative cost savings of $3.6 million over 2 years.…”

Mapping Snakebite Epidemiology in Nicaragua – Pitfalls and Possible Solutions by Erik Hansson (236706)

“…The effects of the case detection bias on the distribution of resources against snakebites could decrease. Although not yet verified empirically, our study provides an example of how snake bite epidemiology may be investigated in similar settings worldwide at a low cost.…”

Notch blockade altered protein expression of inflammatory cytokines, iNOS and nitric oxide (NO) secretion in hypoxic BV-2 cells. by Linli Yao (480545)

“…The upper panel shows specific bands of TNF-α (25.6 k Da), IL-1β (17 kDa), iNOS (130 kDa) and β-actin (43 kDa) (A); TGF-β1 (25 kDa), M-CSF (18.5 kDa), IL-10 (17 kDa) and β-actin (43 kDa) (B). …”

Omega-3 Fatty Acid Supplementation for 12 Weeks Increases Resting and Exercise Metabolic Rate in Healthy Community-Dwelling Older Females by Samantha L. Logan (838281)

“…These changes may predispose older adults to chronic disease and functional impairment; ultimately resulting in a decrease in the quality of life. Research has suggested that long chain omega-3 fatty acids, found predominantly in fatty fish, may assist in reducing these changes. …”

Table_1_Effect of an anti-methanogenic supplement on enteric methane emission, fermentation, and whole rumen metagenome in sheep.DOCX by Pradeep Kumar Malik (12210266)

“…In conclusion, the anti-methanogenic supplement has the potential to decrease enteric methane emission (~22%) at the recommended level (5% of DM) of supplementation. …”

Image_1_Acid- and Volume-Sensitive Chloride Currents in Human Chondrocytes.JPEG by Michael Kittl (9637100)

“…Intracellular pH was assessed by BCECF fluorescence, CV measurements were performed using the Coulter method, and cell viability/cell death by a resazurin assay. Hypotonic cell swelling caused activation of a volume-sensitive outwardly rectifying (VSOR) Cl^– current followed by a regulatory volume decrease (RVD), which was attenuated by the Cl^– channel blocker DCPIB. …”

Table_2_Complete and rapid regeneration of fragments from the upside-down jellyfish Cassiopea.xlsx by Malte Ostendarp (13217973)

“…Over a total observation period of 5 weeks, we regularly monitored survival, pulsation behavior, growth and the regeneration pattern of fragments. …”

Epigenetic Changes during Hepatic Stellate Cell Activation by Silke Götze (111288)

“…</p><p>Methods and Results</p><p>The analysis of DNA methylation changes by antibody-based assays revealed a strong decrease in the global DNA methylation level during culture-induced activation of HSC. …”

DataSheet1_Unraveling the therapeutic mechanisms of dichloroacetic acid in lung cancer through integrated multi-omics approaches: metabolomics and transcriptomics.CSV by Malong Feng (16076690)

“…</p><p>Methods: We conducted a comprehensive analysis of publicly available RNA-seq and metabolomic datasets and established a subcutaneous xenograft model of lung cancer in BALB/c nude mice (n = 5 per group) treated with DCA (50 mg/kg, administered via intraperitoneal injection). …”

DataSheet_2_Asparagus officinalis Exhibits Anti-Tumorigenic and Anti-Metastatic Effects in Ovarian Cancer.pdf by Guangxu Xu (11130687)

“…Asparagus officinalis decreased cellular viability, caused cell cycle G1 phase arrest and induced apoptosis in the OVCAR5 and SKOV3 cells. …”

Systematic Identification of mRNAs Recruited to Argonaute 2 by Specific microRNAs and Corresponding Changes in Transcript Abundance by David G. Hendrickson (257868)

“…Hundreds of mRNAs were recruited to Ago2 by each miRNA via seed sequences in 3′-untranslated regions and coding sequences and a few mRNAs appear to be targeted via seed sequences in 5′-untranslated regions. …”

Nucleoside Drugs Induce Cellular Differentiation by Caspase-Dependent Degradation of Stem Cell Factors by Tanja Musch (249109)

“…Two of them, 3-Deazaneplanocin A (DZNep) and 2′-deoxy-5-azacytidine (decitabine), also induced a decrease in global DNA methylation. …”

Hilar GABAergic neurons segregate into 3 main clusters. by Quentin Perrenoud (2150095)

“…Parameters were considered significant (*; red label) when shuffling resulted in a decrease in mean silhouette value more than 95% of the times. …”

Table_3_Complete and rapid regeneration of fragments from the upside-down jellyfish Cassiopea.xlsx by Malte Ostendarp (13217973)

“…Over a total observation period of 5 weeks, we regularly monitored survival, pulsation behavior, growth and the regeneration pattern of fragments. …”