Data Sheet 1_Prehospital tranexamic acid decreases early mortality in trauma patients: a systematic review and meta-analysis.docx by Yi Li (1144)

“…Data were pooled under a random- or fixed-effects model using RevMan 5.4 with odds ratio (OR) and 95% confidence interval (CI) as the effect measures.…”

Image_1_Decreased Opioid Consumption in Bone Marrow Harvest Patients Using Quadratus Lumborum Blocks in a Standardized Protocol.PDF by Nicole C. McCoy (12459036)

“…The implementation group showed significantly reduced median intraoperative (20.0 mg vs. 0.0 mg; p < 0.001) and total opioid consumption (20.5 mg vs. 0.0 mg; p < 0.001). The number of patients who received any opioids decreased from 84.2% (16/19) before implementation to 23.1% (3/13) after implementation.…”

Image_3_Decreased Opioid Consumption in Bone Marrow Harvest Patients Using Quadratus Lumborum Blocks in a Standardized Protocol.PDF by Nicole C. McCoy (12459036)

“…The implementation group showed significantly reduced median intraoperative (20.0 mg vs. 0.0 mg; p < 0.001) and total opioid consumption (20.5 mg vs. 0.0 mg; p < 0.001). The number of patients who received any opioids decreased from 84.2% (16/19) before implementation to 23.1% (3/13) after implementation.…”

Directed Evolution of RecA Variants with Enhanced Capacity for Conjugational Recombination by Taejin Kim (472963)

“…Three of the variant proteins, RecA I102L, RecA V79L and RecA E86G/C90G were characterized based on their prominence. …”

SEM images (at 100x) of (a-1) polished P110 CS and corroded in 15% HCl for 6h (a) in the absence and presence of (b) 5, (c) 6a and (d) 6b. by Ghadeer Mubarak (21567569)

<b>Reduced legacy precipitation decreases microbial community growth efficiency and alters soil organic carbon in a California grassland</b> by Linnea Honeker (13113813)

Rab7A decreases BST2 cell surface expression and is required for Vpu-induced BST2 cell surface downregulation. by Marina Caillet (198168)

“…<p>(<b>A</b>–<b>B</b>) Rab7A decreases BST2 cell surface expression. …”

Table_1_Complement C5a Induces Pro-inflammatory Microvesicle Shedding in Severely Injured Patients.DOCX by Ebru Karasu (5158097)

“…These data suggest a novel role of the C5a-C5aR1 axis: C5a-induced MV shedding from neutrophils results in decreased C5aR1 surface expression on the one hand, on the other hand it leads to profound inflammatory signals which likely are both key drivers of the neutrophil dysfunction which is regularly observed in patients suffering from multiple traumatic injuries.…”

Image_1_Complement C5a Induces Pro-inflammatory Microvesicle Shedding in Severely Injured Patients.TIF by Ebru Karasu (5158097)

“…These data suggest a novel role of the C5a-C5aR1 axis: C5a-induced MV shedding from neutrophils results in decreased C5aR1 surface expression on the one hand, on the other hand it leads to profound inflammatory signals which likely are both key drivers of the neutrophil dysfunction which is regularly observed in patients suffering from multiple traumatic injuries.…”

Image_4_Complement C5a Induces Pro-inflammatory Microvesicle Shedding in Severely Injured Patients.TIF by Ebru Karasu (5158097)

“…These data suggest a novel role of the C5a-C5aR1 axis: C5a-induced MV shedding from neutrophils results in decreased C5aR1 surface expression on the one hand, on the other hand it leads to profound inflammatory signals which likely are both key drivers of the neutrophil dysfunction which is regularly observed in patients suffering from multiple traumatic injuries.…”

Image_2_Complement C5a Induces Pro-inflammatory Microvesicle Shedding in Severely Injured Patients.TIF by Ebru Karasu (5158097)

“…These data suggest a novel role of the C5a-C5aR1 axis: C5a-induced MV shedding from neutrophils results in decreased C5aR1 surface expression on the one hand, on the other hand it leads to profound inflammatory signals which likely are both key drivers of the neutrophil dysfunction which is regularly observed in patients suffering from multiple traumatic injuries.…”

Image_3_Complement C5a Induces Pro-inflammatory Microvesicle Shedding in Severely Injured Patients.TIF by Ebru Karasu (5158097)

“…These data suggest a novel role of the C5a-C5aR1 axis: C5a-induced MV shedding from neutrophils results in decreased C5aR1 surface expression on the one hand, on the other hand it leads to profound inflammatory signals which likely are both key drivers of the neutrophil dysfunction which is regularly observed in patients suffering from multiple traumatic injuries.…”

Theoretical Study on Reaction Scheme of Silver(I) Containing 5-Substituted Uracils Bridge Formation by Toru Matsui (1313913)

“…The whole reaction scheme is divided into the following three steps: (1) silver ion binding and deprotonation, (2) silver ion transfer, and (3) dimer formation and structural fluctuation. With a new p<i>K</i>_a computing scheme proposed in our previous studies, it is found that a silver coordination decreases the p<i>K</i>_a of <b>N</b> by 2.5–3.0 p<i>K</i>_a units, which is an important clue for silver-ion selectivity by <b>N</b>. …”

Flow chart from invitation to analyses. *For administrative reasons HbA1c was not available for a small subset of the population. by Martin Gillies Banke Rasmussen (10227291)

Longitudinal Lung Function Decrease in Subjects with Spontaneous Healed Pulmonary Tuberculosis by Seung Heon Lee (713097)

“…</p><p>Results</p><p>At baseline, there were no differences in gender, smoking amount, and mean height, except mean age (50.0 ± 8.1 VS. 48.1 ± 7.3, <i>P</i>< 0.001) between the SHPTB and normal group. 52% of the 339 participants with SHPTB and 56% of the 3211 normal participants participated till the end of study. …”

Presentation 1_Loss-of-function mitochondrial DNA polymerase gamma variants cause vascular smooth muscle cells to secrete a diffusible mitogenic factor.pdf by Samantha Rothwell (20733932)

“…Live-cell imaging growth analyses again showed increased growth in A7r5 cells transfected with p.Tyr955Cys but a decreased growth with p.Arg1138Cys, while p.Tyr955Cys increased growth of HeLa cells. …”

TNF-α inhibited A549 cell viability, increased paracellular permeability, HIF-1α expression and decreased VASP expression. by Mengjie Tang (602523)

LARP1 regulates Netrin-1 microsomal translation. by Marie-Laure Plissonnier (337713)

“…LARP1 depletion decreases the expression of Netrin-1 protein in microsomes in Huh7.5 cells. …”

Effect of IDO on brain 5-HT level. by Masatoshi Ohnishi (14587632)

Epidermal Growth Factor Receptor-Dependent Mutual Amplification between Netrin-1 and the Hepatitis C Virus by Marie-Laure Plissonnier (337713)

“…Knockdown and forced expression experiments identified the receptor uncoordinated receptor-5 (UNC5A) as an antagonist of the Netrin-1 signal, though it did not affect the death of HCV-infected cells. …”