Isoflurane, not sevoflurane, inhibited Akt/Bad signal pathway and decreased Bcl-xL/Bad ratio in the hippocampus of P7 rats (n = 5 in each group). by Yujuan Li (554062)

All-Atom Simulations Reveal the Effect of Membrane Composition on the Signaling of the NKG2A/CD94/HLA‑E Immune Receptor Complex by Martin Ljubič (15680161)

“…Additionally, we found that a large concentration of negative charge at the surface of the POPA-based membrane greatly increased the number of contacts with lipid molecules and significantly decreased the exposure of intracellular NKG2A ITIM regions to water molecules, thus likely halting the signal transduction process. …”

MSCs decrease the splenic Th17/Treg ratio and mRNA levels of pro-inflammatory cytokines in the ankle joint. by Kijun Lee (4888660)

Raw images of all western blots presented in Fig 5. by Xianghong Kuang (17811238)

A-p50 affects tumor cell survival through inhibition of NF-κB-mediated transcriptional activation by Jing Mi (18654)

“…</p><p>© 2006 The Author(s)</p> () MTT assay of cell viability. Ad-A-p50-infected A549 cells show a significant decrease in cell viability (Ad-A-p50) compared to Ad-siNT-infected cells, = 3–5 per group, = 0.0001. () Hoechst 33342 staining of apoptotic nuclei. …”

A prepubertal CD decreases hepatic DNA methylation and increases hydroxymethylation in adulthood despite a chronic HFD in Sprague-Dawley male rats. by Ana Aguilar-Lozano (20614619)

Halo-PROTAC mediated zDHHC-PAT degradation decreases substrate palmitoylation in Flp-In 293 T-REx cells. by Mingjie Bai (10028513)

A Single Amino Acid Deletion (ΔF1502) in the S6 Segment of Ca_V2.1 Domain III Associated with Congenital Ataxia Increases Channel Activity and Promotes Ca²⁺ In... by Maria Isabel Bahamonde (840859)

“…Here, we report a second case of congenital ataxia linked to the ΔF1502 α_1A mutation, detected by whole-exome sequencing, and analyze its functional consequences on Ca_V2.1 human channels heterologously expressed in mammalian tsA-201 HEK cells, using the physiological permeant ion Ca²⁺. …”

Identifying Loci Contributing to Natural Variation in Xenobiotic Resistance in <i>Drosophila</i> by Michael A. Najarro (831657)

“…Our goal is to genetically dissect variation in the response to xenobiotics, and characterize naturally-segregating polymorphisms that modulate toxicity. Here, we use the <i>Drosophila</i> Synthetic Population Resource (DSPR), a multiparent advanced intercross panel of recombinant inbred lines, to identify QTL (Quantitative Trait Loci) underlying xenobiotic resistance, and employ caffeine as a model toxic compound. …”

Sociodemographics characteristics of late adolescents who had a pregnancy or children in the past five years preceding the survey in Ethiopia (n = 2210). by Nega Tezera Assimamaw (9662208)

MiR-186 directly targets the NR5A2 gene. by Zheng-liang Zhang (700020)

“…(C) The intensity of EGFP fluorescence was decreased in cancer cells transfected with both miR-186 mimics and NR5A2 WT 3′-UTR, but was unaltered in those transfected with both miR-186 mimics and the 3′-UTR mutant vector. …”

<i>Bahd1</i>-knockout mice display decreased weight and fat mass and lower cholesterol, glucose and leptin levels. by Goran Lakisic (2551717)

Influence of Familial Renal Glycosuria Due to Mutations in the <i>SLC5A2</i> Gene on Changes in Glucose Tolerance over Time by Emilia Ottosson-Laakso (843794)

“…Here we present data on a large pedigree with renal glycosuria due to two mutations (c.300-303+2del and p.A343V) in the <i>SLC5A2</i> gene. …”

Conditional knockout of SLAMF5 in CX3CR1^er cells attenuates EAE progression, reduces brain myeloid cell activation, and decreases T cell infiltration. by Laura Bellassen (22209109)

Mice lacking the type 4 melanocortin receptor have a normal muscle fiber type distribution with a decreased resting heart rate. by Theodore P. Braun (228920)

“…<p>Skeletal and cardiac muscle was examined in in 11-week old male WT (n = 5) and MC4RKO (n = 6) mice. (<b>A</b>) Resting heart rate was decreased in MC4RKO mice. …”

<i>In vivo</i> quantification and characterization of MP populations 5 days after TK-I/R injury. by Viktoriya Rybalko (840821)

Immunostaining of SARS-CoV-2 proteins. by Corantin Maurin (9155070)

Effect of miR-151a-5p knockdown on prostate cancer cell migration and invasion. by Takeshi Chiyomaru (140914)

“…**,P<0.0001 (B) Knockdown of miR-151a-5p significantly decreased cell invasion. Representative images of invasion assay are shown at x200 magnification. …”

Supplementary Material for: Trichostatin A Induces Autophagy in Cervical Cancer Cells by Regulating the PRMT5-STC1-TRPV6-JNK Pathway by Liu J.-H. (4154377)

“…Expression of transient receptor potential cation channel, subfamily V, member 6 (TRPV6), protein arginine methyltransferase 5 (PRMT5), and stanniocalcin 1 (STC1) was determined by qRT-PCR and Western blotting. …”

Huperzine A decreased HiLyte-Aβ₄₂ fluorescent signals colocalized with mitochondrial marker in primary rat neurons. by Yun Lei (495070)