The GON domain expression alters dauer formation and longevity. by Sawako Yoshina (375229)

RAB-5 Controls the Cortical Organization and Dynamics of PAR Proteins to Maintain <em>C. elegans</em> Early Embryonic Polarity by Vincent Hyenne (169009)

“…Using Total Internal Reflection Fluorescence (TIRF) microscopy, we observed that PAR-6 is localized at the cell cortex in highly dynamic puncta and depleting RAB-5 decreased PAR-6 cortical dynamics during the polarity maintenance phase. …”

NeuN expression and neuronal apoptosis in Sham and severely injured groups. by Xinhui Zhang (1624039)

Kinetics of SARS-CoV-2 specific IgM and IgG responses in COVID-19 patients by Baoqing Sun (558067)

“…Serum antibody testing is becoming one of the critical methods for the diagnosis of COVID-19 patients. We investigated IgM and IgG responses against SARS-CoV-2 nucleocapsid (N) and spike (S) protein after symptom onset in the intensive care unit (ICU) and non-ICU patients. 130 blood samples from 38 COVID-19 patients were collected. …”

Table_1_Dietary Fiber Is Essential to Maintain Intestinal Size, L-Cell Secretion, and Intestinal Integrity in Mice.docx by Jenna Elizabeth Hunt (10200959)

“…However, we could not show that the fiber-dependent size decrease was dependent on GLP-1 receptor, GLP-2 receptor or TGR5 signaling. …”

Image_1_Dietary Fiber Is Essential to Maintain Intestinal Size, L-Cell Secretion, and Intestinal Integrity in Mice.pdf by Jenna Elizabeth Hunt (10200959)

“…However, we could not show that the fiber-dependent size decrease was dependent on GLP-1 receptor, GLP-2 receptor or TGR5 signaling. …”

Explicit, color association report task results. by Talia L. Retter (16520742)

Genetic and epigenetic profiling of the infertile male by Stephanie Cheung (254096)

“…In the infertile cohort, we identified 17 genes with the highest mutation rate, engaged in key roles of gametogenesis, fertilization and embryo development. …”

Development and characterization of a bivalent mRNA vaccine targeting the Delta and Omicron variants of SARS-CoV-2 by Xiao-Chuan Xiong (22337097)

“…Then, the immunogenicity of the vaccine candidates under a two-dose prime immunization regimen were further analyzed, demonstrating that ARCoV-Biv induced a broad neutralizing antibody response, with mean neutralization titers (NT50) of 87,556.33 against Delta (B.1.617.2) and 52,634.67 against Omicron BA.1, representing 71.19-fold and 399.72-fold increases, respectively, compared to the levels prior to booster immunization. …”

DataSheet_1_Heterogeneous SARS-CoV-2-Neutralizing Activities After Infection and Vaccination.pdf by Marianne Graninger (12696830)

“…Background<p>Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) with different resistance levels to existing immunity have recently emerged. …”

Nrf2 is necessary for optimal PMN migration toward CXCL12 and CXCL2 without regulating receptors expression. by Doumet Georges Helou (7255823)

TRPC channels regulate Ca²⁺-signaling and short-term plasticity of fast glutamatergic synapses by Yvonne Schwarz (7406756)

“…Specifically, loss of TRPC1/C4/C5 channels decreases basal-evoked secretion, reduces the pool size of readily releasable vesicles, and accelerates synaptic depression during high-frequency stimulation (HFS). …”

2‑Ethylhexyl Diphenyl Phosphate and Its Hydroxylated Metabolites are Anti-androgenic and Cause Adverse Reproductive Outcomes in Male Japanese Medaka (Oryzias latipes) by Yu Li (183836)

“…Although high concentrations of 2-ethylhexyl diphenyl phosphate (EHDPP) have been detected in wild fish, its reproductive toxicity in fish remains unclear. In this study, we for the first time observed that EHDPP elicited androgen receptor (AR) antagonistic activity with a 50% inhibitory concentration of 37.5 μM. 2-Ethyl-5-hydroxyhexyl diphenyl phosphate was proved to be the dominant metabolite of EHDPP in Japanese medaka and elicited 3.1-fold stronger AR antagonistic activity than that of EHDPP. …”

2‑Ethylhexyl Diphenyl Phosphate and Its Hydroxylated Metabolites are Anti-androgenic and Cause Adverse Reproductive Outcomes in Male Japanese Medaka (Oryzias latipes) by Yu Li (183836)

“…Although high concentrations of 2-ethylhexyl diphenyl phosphate (EHDPP) have been detected in wild fish, its reproductive toxicity in fish remains unclear. In this study, we for the first time observed that EHDPP elicited androgen receptor (AR) antagonistic activity with a 50% inhibitory concentration of 37.5 μM. 2-Ethyl-5-hydroxyhexyl diphenyl phosphate was proved to be the dominant metabolite of EHDPP in Japanese medaka and elicited 3.1-fold stronger AR antagonistic activity than that of EHDPP. …”

Table_5_Risk Factors and Nomogram for Predicting Relapse Risk in Pediatric Neuromyelitis Optica Spectrum Disorders.xlsx by Shanchao Zhang (500712)

“…A nomogram was generated to assess relapse attacks in 1-year follow-up. Thirty-five patients from 3 other centers formed an external cohort to validate this nomogram.…”

Loss of MALS-1 function suppresses the mitochondrial and axon degeneration phenotypes that are caused by loss of RBM-26 function. by Tamjid A. Chowdhury (14149846)

“…CRISPR was also used to insert a 3X FLAG tag at the C-terminus of MRPL-58 in <i>mals-1(syb6330)</i> mutant to create <i>mrpl-58(cue50) mals-1(syb6330)</i>. Finally, <i>rbm-26 (P80L)</i> mutation was inserted into <i>mrpl-58(cue50) mals-1(syb6330)</i> to create <i>rbm-26(cue51 [P80L]) mrpl-58(cue50) mals-1(syb6330)</i>, and 25 μg of total protein lysate from mixed stage population were loaded per lane and specific proteins were detected with an anti-FLAG antibody and enhanced chemiluminescence. …”

The Deoxyhypusine Synthase Mutant <i>dys1-1</i> Reveals the Association of eIF5A and Asc1 with Cell Wall Integrity by Fabio Carrilho Galvão (396804)

“…In this study, we generated and characterized the <i>dys1-1</i> mutant, which showed a strong depletion of mutated Dys1 protein, resulting in more than 2-fold decrease in hypusine levels relative to the wild type. …”

Old rat serum present higher levels of pro-inflammatory cytokine. by María Paz Saldías (4430032)

The lack of Nrf2 does not affect PMN phagocytic capacity. by Doumet Georges Helou (7255823)

Psychosine-induced changes vimentin in human astrocytes and is partially reversed by DEDA. by Cedric Misslin (4567393)